Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-κB-responsive genes in cervical keratinocytes M Nees, JM Geoghegan, T Hyman, S Frank, L Miller, CD Woodworth Journal of virology 75 (9), 4283-4296, 2001 | 518 | 2001 |
A comprehensive panel of three-dimensional models for studies of prostate cancer growth, invasion and drug responses V Härmä, J Virtanen, R Mäkelä, A Happonen, JP Mpindi, M Knuuttila, ... PloS one 5 (5), e10431, 2010 | 432 | 2010 |
Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues S Kilpinen, R Autio, K Ojala, K Iljin, E Bucher, H Sara, T Pisto, M Saarela, ... Genome biology 9, 1-14, 2008 | 331 | 2008 |
FZD4 as a Mediator of ERG Oncogene–Induced WNT Signaling and Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells S Gupta, K Iljin, H Sara, JP Mpindi, T Mirtti, P Vainio, J Rantala, K Alanen, ... Cancer research 70 (17), 6735-6745, 2010 | 316 | 2010 |
TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming K Iljin, M Wolf, H Edgren, S Gupta, S Kilpinen, RI Skotheim, M Peltola, ... Cancer research 66 (21), 10242-10246, 2006 | 307 | 2006 |
Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis S Pollari, SM Käkönen, H Edgren, M Wolf, P Kohonen, H Sara, T Guise, ... Breast cancer research and treatment 125, 421-430, 2011 | 290 | 2011 |
Alternative splicing in cancer: noise, functional, or systematic? RI Skotheim, M Nees The international journal of biochemistry & cell biology 39 (7-8), 1432-1449, 2007 | 281 | 2007 |
Expression of mutated p53 occurs in tumor-distant epithelia of head and neck cancer patients: a possible molecular basis for the development of multiple tumors M Nees, N Homann, H Discher, T Andl, C Enders, C Herold-Mende, ... Cancer research 53 (18), 4189-4196, 1993 | 243 | 1993 |
Detection of integrated papillomavirus sequences by ligation‐mediated PCR (DIPS‐PCR) and molecular characterization in cervical cancer cells F Luft, R Klaes, M Nees, M Dürst, V Heilmann, P Melsheimer, ... International journal of cancer 92 (1), 9-17, 2001 | 212 | 2001 |
Identification of potential markers for the detection of pancreatic cancer through comparative serum protein expression profiling M Ehmann, K Felix, D Hartmann, M Schnölzer, M Nees, ... Pancreas 34 (2), 205-214, 2007 | 200 | 2007 |
In search of the Holy Grail: folate-targeted nanoparticles for cancer therapy A Garcia-Bennett, M Nees, B Fadeel Biochemical pharmacology 81 (8), 976-984, 2011 | 162 | 2011 |
Proteomic analysis reveals successive aberrations in protein expression from healthy mucosa to invasive head and neck cancer M Roesch-Ely, M Nees, S Karsai, A Ruess, R Bogumil, U Warnken, ... Oncogene 26 (1), 54-64, 2007 | 152 | 2007 |
c-Myc modulation and acetylation is a key HDAC inhibitor target in cancer A Nebbioso, V Carafa, M Conte, FP Tambaro, C Abbondanza, J Martens, ... Clinical Cancer Research 23 (10), 2542-2555, 2017 | 143 | 2017 |
Inhibition of the epidermal growth factor receptor increases expression of genes that stimulate inflammation, apoptosis, and cell attachment CD Woodworth, E Michael, D Marker, S Allen, L Smith, M Nees Molecular cancer therapeutics 4 (4), 650-658, 2005 | 140 | 2005 |
Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion M Björkman, P Östling, V Härmä, J Virtanen, JP Mpindi, J Rantala, T Mirtti, ... Oncogene 31 (29), 3444-3456, 2012 | 136 | 2012 |
Human papillomavirus type 16 E6 and E7 proteins inhibit differentiation-dependent expression of transforming growth factor-β2 in cervical keratinocytes M Nees, JM Geoghegan, P Munson, V Prabhu, Y Liu, E Androphy, ... Cancer research 60 (15), 4289-4298, 2000 | 131 | 2000 |
Quantification of dynamic morphological drug responses in 3D organotypic cell cultures by automated image analysis V Härmä, HP Schukov, A Happonen, I Ahonen, J Virtanen, H Siitari, ... PloS one 9 (5), e96426, 2014 | 104 | 2014 |
Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer V Murillo-Garzón, I Gorroño-Etxebarria, M Åkerfelt, MC Puustinen, ... Nature communications 9 (1), 1747, 2018 | 100 | 2018 |
Validation of proposed prostate cancer biomarkers with gene expression data: a long road to travel A Amaro, AI Esposito, A Gallina, M Nees, G Angelini, A Albini, U Pfeffer Cancer and Metastasis Reviews 33, 657-671, 2014 | 97 | 2014 |
Tumor necrosis factor‐α promotes human papillomavirus (HPV) E6/E7 RNA expression and cyclin‐dependent kinase activity in HPV‐immortalized keratinocytes by a ras‐dependent pathway D Gaiotti, J Chung, M Iglesias, M Nees, PD Baker, CH Evans, ... Molecular carcinogenesis 27 (2), 97-109, 2000 | 95 | 2000 |