Protein− DNA binding in the absence of specific base-pair recognition A Afek, JL Schipper, J Horton, R Gordân, DB Lukatsky Proceedings of the National Academy of Sciences 111 (48), 17140-17145, 2014 | 117 | 2014 |
DNA mismatches reveal conformational penalties in protein–DNA recognition A Afek, H Shi, A Rangadurai, H Sahay, A Senitzki, S Xhani, M Fang, ... Nature 587 (7833), 291-296, 2020 | 108 | 2020 |
Short tandem repeats bind transcription factors to tune eukaryotic gene expression CA Horton, AM Alexandari, MGB Hayes, E Marklund, JM Schaepe, ... Science 381 (6664), eadd1250, 2023 | 79 | 2023 |
Unexpected implications of STAT3 acetylation revealed by genetic encoding of acetyl-lysine Y Belo, Z Mielko, H Nudelman, A Afek, O Ben-David, A Shahar, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (9), 1343-1350, 2019 | 48 | 2019 |
QBiC-Pred: quantitative predictions of transcription factor binding changes due to sequence variants V Martin, J Zhao, A Afek, Z Mielko, R Gordân Nucleic acids research 47 (W1), W127-W135, 2019 | 38 | 2019 |
Nonspecific transcription-factor-DNA binding influences nucleosome occupancy in yeast A Afek, I Sela, N Musa-Lempel, DB Lukatsky Biophysical journal 101 (10), 2465-2475, 2011 | 33 | 2011 |
Genome-wide organization of eukaryotic preinitiation complex is influenced by nonconsensus protein-DNA binding A Afek, DB Lukatsky Biophysical journal 104 (5), 1107-1115, 2013 | 29 | 2013 |
Nonconsensus protein binding to repetitive DNA sequence elements significantly affects eukaryotic genomes A Afek, H Cohen, S Barber-Zucker, R Gordân, DB Lukatsky PLoS computational biology 11 (8), e1004429, 2015 | 25 | 2015 |
Nonspecific protein-DNA binding is widespread in the yeast genome A Afek, DB Lukatsky Biophysical journal 102 (8), 1881-1888, 2012 | 25 | 2012 |
Positive and negative design for nonconsensus protein-DNA binding affinity in the vicinity of functional binding sites A Afek, DB Lukatsky Biophysical journal 105 (7), 1653-1660, 2013 | 24 | 2013 |
Multi-scale sequence correlations increase proteome structural disorder and promiscuity A Afek, EI Shakhnovich, DB Lukatsky Journal of molecular biology 409 (3), 439-449, 2011 | 17 | 2011 |
Sequence correlations shape protein promiscuity DB Lukatsky, A Afek, EI Shakhnovich The Journal of chemical physics 135 (6), 2011 | 14 | 2011 |
Deciphering the Role of the Ser‐Phosphorylation Pattern on the DNA‐Binding Activity of Max Transcription Factor Using Chemical Protein Synthesis RV Nithun, YM Yao, X Lin, S Habiballah, A Afek, M Jbara Angewandte Chemie International Edition 62 (47), e202310913, 2023 | 11 | 2023 |
UV irradiation remodels the specificity landscape of transcription factors Z Mielko, Y Zhang, H Sahay, Y Liu, MA Schaich, B Schnable, AM Morrison, ... Proceedings of the National Academy of Sciences 120 (11), e2217422120, 2023 | 11 | 2023 |
Control of transcription initiation by biased thermal fluctuations on repetitive genomic sequences M Imashimizu, Y Tokunaga, A Afek, H Takahashi, N Shimamoto, ... Biomolecules 10 (9), 1299, 2020 | 8 | 2020 |
Toward deciphering the mechanistic role of variations in the Rep1 repeat site in the transcription regulation of SNCA gene A Afek, L Tagliafierro, OC Glenn, DB Lukatsky, R Gordan, O Chiba-Falek neurogenetics 19, 135-144, 2018 | 8 | 2018 |
Control of transcriptional pausing by biased thermal fluctuations on repetitive genomic sequences M Imashimizu, A Afek, H Takahashi, L Lubkowska, DB Lukatsky Proceedings of the National Academy of Sciences 113 (47), E7409-E7417, 2016 | 8 | 2016 |
DNA sequence context controls the binding and processivity of the T7 DNA primase A Afek, S Ilic, J Horton, DB Lukatsky, R Gordan, B Akabayov Iscience 2, 141-147, 2018 | 7 | 2018 |
Site-Specific Acetylation of the Transcription Factor Protein Max Modulates Its DNA Binding Activity RV Nithun, YM Yao, O Harel, S Habiballah, A Afek, M Jbara ACS Central Science, 2024 | 3 | 2024 |
Short tandem repeats recruit transcription factors to tune eukaryotic gene expression CA Horton, AM Alexandari, MG Hayes, JM Schaepe, E Marklund, N Shah, ... Biophysical Journal 121 (3), 287a-288a, 2022 | 3 | 2022 |