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Ariel Afek
Ariel Afek
Department of Chemical and Structural Biology, Weizmann Institute of Science
Verified email at weizmann.ac.il
Title
Cited by
Cited by
Year
Protein− DNA binding in the absence of specific base-pair recognition
A Afek, JL Schipper, J Horton, R Gordân, DB Lukatsky
Proceedings of the National Academy of Sciences 111 (48), 17140-17145, 2014
1172014
DNA mismatches reveal conformational penalties in protein–DNA recognition
A Afek, H Shi, A Rangadurai, H Sahay, A Senitzki, S Xhani, M Fang, ...
Nature 587 (7833), 291-296, 2020
1082020
Short tandem repeats bind transcription factors to tune eukaryotic gene expression
CA Horton, AM Alexandari, MGB Hayes, E Marklund, JM Schaepe, ...
Science 381 (6664), eadd1250, 2023
792023
Unexpected implications of STAT3 acetylation revealed by genetic encoding of acetyl-lysine
Y Belo, Z Mielko, H Nudelman, A Afek, O Ben-David, A Shahar, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (9), 1343-1350, 2019
482019
QBiC-Pred: quantitative predictions of transcription factor binding changes due to sequence variants
V Martin, J Zhao, A Afek, Z Mielko, R Gordân
Nucleic acids research 47 (W1), W127-W135, 2019
382019
Nonspecific transcription-factor-DNA binding influences nucleosome occupancy in yeast
A Afek, I Sela, N Musa-Lempel, DB Lukatsky
Biophysical journal 101 (10), 2465-2475, 2011
332011
Genome-wide organization of eukaryotic preinitiation complex is influenced by nonconsensus protein-DNA binding
A Afek, DB Lukatsky
Biophysical journal 104 (5), 1107-1115, 2013
292013
Nonconsensus protein binding to repetitive DNA sequence elements significantly affects eukaryotic genomes
A Afek, H Cohen, S Barber-Zucker, R Gordân, DB Lukatsky
PLoS computational biology 11 (8), e1004429, 2015
252015
Nonspecific protein-DNA binding is widespread in the yeast genome
A Afek, DB Lukatsky
Biophysical journal 102 (8), 1881-1888, 2012
252012
Positive and negative design for nonconsensus protein-DNA binding affinity in the vicinity of functional binding sites
A Afek, DB Lukatsky
Biophysical journal 105 (7), 1653-1660, 2013
242013
Multi-scale sequence correlations increase proteome structural disorder and promiscuity
A Afek, EI Shakhnovich, DB Lukatsky
Journal of molecular biology 409 (3), 439-449, 2011
172011
Sequence correlations shape protein promiscuity
DB Lukatsky, A Afek, EI Shakhnovich
The Journal of chemical physics 135 (6), 2011
142011
Deciphering the Role of the Ser‐Phosphorylation Pattern on the DNA‐Binding Activity of Max Transcription Factor Using Chemical Protein Synthesis
RV Nithun, YM Yao, X Lin, S Habiballah, A Afek, M Jbara
Angewandte Chemie International Edition 62 (47), e202310913, 2023
112023
UV irradiation remodels the specificity landscape of transcription factors
Z Mielko, Y Zhang, H Sahay, Y Liu, MA Schaich, B Schnable, AM Morrison, ...
Proceedings of the National Academy of Sciences 120 (11), e2217422120, 2023
112023
Control of transcription initiation by biased thermal fluctuations on repetitive genomic sequences
M Imashimizu, Y Tokunaga, A Afek, H Takahashi, N Shimamoto, ...
Biomolecules 10 (9), 1299, 2020
82020
Toward deciphering the mechanistic role of variations in the Rep1 repeat site in the transcription regulation of SNCA gene
A Afek, L Tagliafierro, OC Glenn, DB Lukatsky, R Gordan, O Chiba-Falek
neurogenetics 19, 135-144, 2018
82018
Control of transcriptional pausing by biased thermal fluctuations on repetitive genomic sequences
M Imashimizu, A Afek, H Takahashi, L Lubkowska, DB Lukatsky
Proceedings of the National Academy of Sciences 113 (47), E7409-E7417, 2016
82016
DNA sequence context controls the binding and processivity of the T7 DNA primase
A Afek, S Ilic, J Horton, DB Lukatsky, R Gordan, B Akabayov
Iscience 2, 141-147, 2018
72018
Site-Specific Acetylation of the Transcription Factor Protein Max Modulates Its DNA Binding Activity
RV Nithun, YM Yao, O Harel, S Habiballah, A Afek, M Jbara
ACS Central Science, 2024
32024
Short tandem repeats recruit transcription factors to tune eukaryotic gene expression
CA Horton, AM Alexandari, MG Hayes, JM Schaepe, E Marklund, N Shah, ...
Biophysical Journal 121 (3), 287a-288a, 2022
32022
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