| Rule‐based modeling: a computational approach for studying biomolecular site dynamics in cell signaling systems LA Chylek, LA Harris, CS Tung, JR Faeder, CF Lopez, WS Hlavacek Wiley Interdisciplinary Reviews: Systems Biology and Medicine 6 (1), 13-36, 2014 | 168 | 2014 |
| Receptor-driven ERK pulses reconfigure MAPK signaling and enable persistence of drug-adapted BRAF-mutant melanoma cells L Gerosa, C Chidley, F Fröhlich, G Sanchez, SK Lim, J Muhlich, JY Chen, ... Cell systems 11 (5), 478-494. e9, 2020 | 107 | 2020 |
| Phosphorylation site dynamics of early T-cell receptor signaling LA Chylek, V Akimov, J Dengjel, KTG Rigbolt, B Hu, WS Hlavacek, ... PloS one 9 (8), e104240, 2014 | 76 | 2014 |
| Modeling for (physical) biologists: an introduction to the rule-based approach LA Chylek, LA Harris, JR Faeder, WS Hlavacek Physical biology 12 (4), 045007, 2015 | 72 | 2015 |
| Guidelines for visualizing and annotating rule-based models LA Chylek, B Hu, ML Blinov, T Emonet, JR Faeder, B Goldstein, ... Molecular BioSystems 7 (10), 2779-2795, 2011 | 58 | 2011 |
| BioNetFit: a fitting tool compatible with BioNetGen, NFsim and distributed computing environments BR Thomas, LA Chylek, J Colvin, S Sirimulla, AHA Clayton, WS Hlavacek, ... Bioinformatics 32 (5), 798-800, 2016 | 41 | 2016 |
| Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling V Vemulapalli, LA Chylek, A Erickson, A Pfeiffer, KH Gabriel, ... Elife 10, e64251, 2021 | 30 | 2021 |
| An interaction library for the FcϵRI signaling network LA Chylek, DA Holowka, BA Baird, WS Hlavacek T Cell Biology 5, 172, 2014 | 30* | 2014 |
| Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework BA Petros, JS Paull, CH Tomkins-Tinch, BC Loftness, KC DeRuff, P Nair, ... Med 3 (12), 883-900. e13, 2022 | 26 | 2022 |
| Innovations of the rule-based modeling approach LA Chylek, EC Stites, RG Posner, WS Hlavacek Systems Biology: integrative biology and simulation tools, 273-300, 2013 | 25 | 2013 |
| Timescale separation of positive and negative signaling creates history-dependent responses to IgE receptor stimulation B Harmon, LA Chylek, Y Liu, ED Mitra, A Mahajan, EA Saada, ... Scientific reports 7 (1), 15586, 2017 | 20 | 2017 |
| Modeling biomolecular site dynamics in immunoreceptor signaling systems LA Chylek, BS Wilson, WS Hlavacek A Systems Biology Approach to Blood. Springer, 2014 | 13 | 2014 |
| Considerations for the selection and use of disinfectants against SARS-CoV-2 in a health care setting K Tyan, A Levin, A Avalos-Pacheco, D Plana, EA Rand, H Yang, ... Open forum infectious diseases 7 (9), ofaa396, 2020 | 10 | 2020 |
| Systems biology: Integrative biology and simulation tools LA Chylek, EC Stites, RG Posner, WS Hlavacek Springer, 2013 | 8 | 2013 |
| Time resolved quantitative phosphoproteomics reveals distinct patterns of SHP2 dependence in EGFR signaling V Vemulapalli, L Chylek, A Erickson, J LaRochelle, K Subramanian, ... bioRxiv, 598664, 2019 | 7 | 2019 |
| Decoding the language of phosphorylation site dynamics LA Chylek Science Signaling 6 (274), jc2-jc2, 2013 | 6 | 2013 |
| Quantitative modeling of mast cell signaling LA Chylek, DA Holowka, BA Baird, WS Hlavacek Systems Immunology, 213-226, 2018 | 2 | 2018 |
| Using equation-free computation to accelerate network-free stochastic simulation of chemical kinetics YT Lin, LA Chylek, NW Lemons, WS Hlavacek The Journal of Physical Chemistry B 122 (24), 6351-6356, 2018 | 1 | 2018 |
| Using Mechanistic Models for Analysis of Proteomic Data LA Chylek Modeling Biomolecular Site Dynamics: Methods and Protocols, 265-270, 2019 | | 2019 |
| Modeling and Experimental Characterization of IgE Receptor Signaling to Develop New Drugs for Allergies P Velappan, A Ionkov, A Drew, N Velappan, L Naranjo, A Bradbury, ... | | 2016 |
William S. HlavacekTheoretical Division, Los Alamos National LaboratoryVerified email at lanl.gov