| pH dependence of the urea and guanidine hydrochloride denaturation of ribonuclease A and ribonuclease T1 CN Pace, DV Laurents, JA Thomson Biochemistry 29 (10), 2564-2572, 1990 | 447 | 1990 |
| The cadherin cytoplasmic domain is unstructured in the absence of β-catenin: a possible mechanism for regulating cadherin turnover AH Huber, DB Stewart, DV Laurents, WJ Nelson, WI Weis Journal of Biological Chemistry 276 (15), 12301-12309, 2001 | 362 | 2001 |
| A new method for determining the heat capacity change for protein folding CN Pace, DV Laurents Biochemistry 28 (6), 2520-2525, 1989 | 263 | 1989 |
| Structural similarity of DNA-binding domains of bacteriophage repressors and the globin core S Subbiah, DV Laurents, M Levitt Current Biology 3 (3), 141-148, 1993 | 246 | 1993 |
| Urea denaturation of barnase: pH dependence and characterization of the unfolded state CN Pace, DV Laurents, RE Erickson Biochemistry 31 (10), 2728-2734, 1992 | 183 | 1992 |
| The TDP‐43 N‐terminal domain structure at high resolution M Mompeán, V Romano, D Pantoja‐Uceda, C Stuani, FE Baralle, ... The FEBS journal 283 (7), 1242-1260, 2016 | 159 | 2016 |
| Charge–charge interactions are key determinants of the pK values of ionizable groups in ribonuclease Sa (pI= 3.5) and a basic variant (pI= 10.2) DV Laurents, BMP Huyghues-Despointes, M Bruix, RL Thurlkill, D Schell, ... Journal of molecular biology 325 (5), 1077-1092, 2003 | 130 | 2003 |
| Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions M Mompeán, V Romano, D Pantoja-Uceda, C Stuani, FE Baralle, E Buratti, ... Journal of Biological Chemistry 292 (28), 11992-12006, 2017 | 96 | 2017 |
| Structural characterization of the minimal segment of TDP-43 competent for aggregation M Mompeán, E Buratti, C Guarnaccia, RMM Brito, A Chakrabartty, ... Archives of biochemistry and biophysics 545, 53-62, 2014 | 92 | 2014 |
| Molecular basis of Orb2 amyloidogenesis and blockade of memory consolidation R Hervas, L Li, A Majumdar, MDC Fernandez-Ramirez, JR Unruh, ... PLoS biology 14 (1), e1002361, 2016 | 88 | 2016 |
| Common features at the start of the neurodegeneration cascade R Hervas, J Oroz, A Galera-Prat, O Goni, A Valbuena, AM Vera, ... PLoS biology 10 (5), e1001335, 2012 | 85 | 2012 |
| Characterization of the unfolding pathway of hen egg white lysozyme DV Laurents, RL Baldwin Biochemistry 36 (6), 1496-1504, 1997 | 83 | 1997 |
| Structural evidence of amyloid fibril formation in the putative aggregation domain of TDP-43 M Mompeán, R Hervás, Y Xu, TH Tran, C Guarnaccia, E Buratti, F Baralle, ... The journal of physical chemistry letters 6 (13), 2608-2615, 2015 | 82 | 2015 |
| Protein folding: matching theory and experiment DV Laurents, RL Baldwin Biophysical journal 75 (1), 428-434, 1998 | 76 | 1998 |
| NMR spectroscopy reveals that RNase A is chiefly denatured in 40% acetic acid: implications for oligomer formation by 3D domain swapping JP Lopez-Alonso, M Bruix, J Font, M Ribo, M Vilanova, MA Jimenez, ... Journal of the American Chemical Society 132 (5), 1621-1630, 2010 | 71 | 2010 |
| AlphaFold 2 and NMR spectroscopy: partners to understand protein structure, dynamics and function DV Laurents Frontiers in molecular biosciences 9, 906437, 2022 | 65 | 2022 |
| Charge substitution shows that repulsive electrostatic interactions impede the oligomerization of Alzheimer amyloid peptides M Guo, PM Gorman, M Rico, A Chakrabartty, DV Laurents FEBS letters 579 (17), 3574-3578, 2005 | 64 | 2005 |
| Molecular mechanism for the synchronized electrostatic coacervation and co-aggregation of alpha-synuclein and tau P Gracia, D Polanco, J Tarancón-Díez, I Serra, M Bracci, J Oroz, ... Nature Communications 13 (1), 4586, 2022 | 55 | 2022 |
| Different protein sequences can give rise to highly similar folds through different stabilizing interactions DV Laurents, S Subbiah, M Levitt Protein Science 3 (11), 1938-1944, 1994 | 55 | 1994 |
| An amyloid-like pathological conformation of TDP-43 is stabilized by hypercooperative hydrogen bonds M Mompeán, M Baralle, E Buratti, DV Laurents Frontiers in molecular neuroscience 9, 125, 2016 | 54 | 2016 |
Miguel MompeánInstituto de Química Física "Blas Cabrera", IQF-CSICVerified email at iqf.csic.es
