The autoimmune regulator PHD finger binds to non‐methylated histone H3K4 to activate gene expression T Org, F Chignola, C Hetényi, M Gaetani, A Rebane, I Liiv, U Maran, ... EMBO reports 9 (4), 370-376, 2008 | 285 | 2008 |
Proteome integral solubility alteration: a high-throughput proteomics assay for target deconvolution M Gaetani, P Sabatier, AA Saei, CM Beusch, Z Yang, SL Lundström, ... Journal of proteome research 18 (11), 4027-4037, 2019 | 206 | 2019 |
Optimization of carotenoid production by Rhodotorula graminis DBVPG 7021 as a function of trace element concentration by means of response surface analysis P Buzzini, A Martini, M Gaetani, B Turchetti, UM Pagnoni, P Davoli Enzyme and Microbial Technology 36 (5-6), 687-692, 2005 | 131 | 2005 |
Dematin and adducin provide a novel link between the spectrin cytoskeleton and human erythrocyte membrane by directly interacting with glucose transporter-1 AA Khan, T Hanada, M Mohseni, JJ Jeong, L Zeng, M Gaetani, D Li, ... Journal of Biological Chemistry 283 (21), 14600-14609, 2008 | 118 | 2008 |
The role of bFGF on the ability of MSC to activate endogenous regenerative mechanisms in an ectopic bone formation model R Tasso, M Gaetani, E Molino, A Cattaneo, M Monticone, A Bachi, ... Biomaterials 33 (7), 2086-2096, 2012 | 100 | 2012 |
The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation F Chignola, M Gaetani, A Rebane, T Org, L Mollica, C Zucchelli, ... Nucleic acids research 37 (9), 2951-2961, 2009 | 99 | 2009 |
ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery AA Saei, CM Beusch, A Chernobrovkin, P Sabatier, B Zhang, ÜG Tokat, ... Nature communications 10 (1), 5715, 2019 | 72 | 2019 |
Anticancer effect of deuterium depleted water-redox disbalance leads to oxidative stress X Zhang, M Gaetani, A Chernobrovkin, RA Zubarev Molecular & Cellular Proteomics 18 (12), 2373-2387, 2019 | 65 | 2019 |
Lysine-specific demethylase 1A restricts ex vivo propagation of human HSCs and is a target of UM171 A Subramaniam, K Žemaitis, MS Talkhoncheh, D Yudovich, A Bäckström, ... Blood, The Journal of the American Society of Hematology 136 (19), 2151-2161, 2020 | 57 | 2020 |
Structural and functional effects of hereditary hemolytic anemia-associated point mutations in the alpha spectrin tetramer site M Gaetani, S Mootien, S Harper, PG Gallagher, DW Speicher Blood, The Journal of the American Society of Hematology 111 (12), 5712-5720, 2008 | 56 | 2008 |
System-wide identification and prioritization of enzyme substrates by thermal analysis AA Saei, CM Beusch, P Sabatier, JA Wells, H Gharibi, Z Meng, ... Nature communications 12 (1), 1296, 2021 | 55 | 2021 |
Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding CP Johnson, M Gaetani, V Ortiz, N Bhasin, S Harper, PG Gallagher, ... Blood 109 (8), 3538-3543, 2007 | 48 | 2007 |
AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome M Gaetani, V Matafora, M Saare, D Spiliotopoulos, L Mollica, G Quilici, ... Nucleic acids research 40 (22), 11756-11768, 2012 | 45 | 2012 |
Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals C Wodarczyk, G Distefano, I Rowe, M Gaetani, B Bricoli, M Muorah, ... PloS one 5 (9), e12719, 2010 | 38 | 2010 |
Capillary leakage provides nutrients and antioxidants for rapid pneumococcal proliferation in influenza-infected lower airways V Sender, K Hentrich, A Pathak, A Tan Qian Ler, BT Embaie, ... Proceedings of the National Academy of Sciences 117 (49), 31386-31397, 2020 | 30 | 2020 |
An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation P Sabatier, CM Beusch, AA Saei, M Aoun, N Moruzzi, A Coelho, N Leijten, ... Nature communications 12 (1), 6558, 2021 | 29 | 2021 |
Unbiased and quantitative proteomics reveals highly increased angiogenesis induction by the secretome of mesenchymal stromal cells isolated from fetal rather than adult skin M Gaetani, CM Chinnici, AP Carreca, C Di Pasquale, G Amico, ... Journal of Tissue Engineering and Regenerative Medicine 12 (2), e949-e961, 2018 | 29 | 2018 |
The common hereditary elliptocytosis-associated α-spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation SL Harper, S Sriswasdi, HY Tang, M Gaetani, PG Gallagher, DW Speicher Blood, The Journal of the American Society of Hematology 122 (17), 3045-3053, 2013 | 28 | 2013 |
The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase LN Heppler, S Attarha, R Persaud, JI Brown, P Wang, B Petrova, I Tošić, ... Journal of Biological Chemistry 298 (2), 2022 | 22 | 2022 |
Thermal proteome profiling identifies oxidative-dependent inhibition of the transcription of major oncogenes as a new therapeutic mechanism for select anticancer compounds S Peuget, J Zhu, G Sanz, M Singh, M Gaetani, X Chen, Y Shi, AA Saei, ... Cancer research 80 (7), 1538-1550, 2020 | 18 | 2020 |