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Massimiliano Gaetani
Massimiliano Gaetani
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The autoimmune regulator PHD finger binds to non‐methylated histone H3K4 to activate gene expression
T Org, F Chignola, C Hetényi, M Gaetani, A Rebane, I Liiv, U Maran, ...
EMBO reports 9 (4), 370-376, 2008
2852008
Proteome integral solubility alteration: a high-throughput proteomics assay for target deconvolution
M Gaetani, P Sabatier, AA Saei, CM Beusch, Z Yang, SL Lundström, ...
Journal of proteome research 18 (11), 4027-4037, 2019
2062019
Optimization of carotenoid production by Rhodotorula graminis DBVPG 7021 as a function of trace element concentration by means of response surface analysis
P Buzzini, A Martini, M Gaetani, B Turchetti, UM Pagnoni, P Davoli
Enzyme and Microbial Technology 36 (5-6), 687-692, 2005
1312005
Dematin and adducin provide a novel link between the spectrin cytoskeleton and human erythrocyte membrane by directly interacting with glucose transporter-1
AA Khan, T Hanada, M Mohseni, JJ Jeong, L Zeng, M Gaetani, D Li, ...
Journal of Biological Chemistry 283 (21), 14600-14609, 2008
1182008
The role of bFGF on the ability of MSC to activate endogenous regenerative mechanisms in an ectopic bone formation model
R Tasso, M Gaetani, E Molino, A Cattaneo, M Monticone, A Bachi, ...
Biomaterials 33 (7), 2086-2096, 2012
1002012
The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation
F Chignola, M Gaetani, A Rebane, T Org, L Mollica, C Zucchelli, ...
Nucleic acids research 37 (9), 2951-2961, 2009
992009
ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery
AA Saei, CM Beusch, A Chernobrovkin, P Sabatier, B Zhang, ÜG Tokat, ...
Nature communications 10 (1), 5715, 2019
722019
Anticancer effect of deuterium depleted water-redox disbalance leads to oxidative stress
X Zhang, M Gaetani, A Chernobrovkin, RA Zubarev
Molecular & Cellular Proteomics 18 (12), 2373-2387, 2019
652019
Lysine-specific demethylase 1A restricts ex vivo propagation of human HSCs and is a target of UM171
A Subramaniam, K Žemaitis, MS Talkhoncheh, D Yudovich, A Bäckström, ...
Blood, The Journal of the American Society of Hematology 136 (19), 2151-2161, 2020
572020
Structural and functional effects of hereditary hemolytic anemia-associated point mutations in the alpha spectrin tetramer site
M Gaetani, S Mootien, S Harper, PG Gallagher, DW Speicher
Blood, The Journal of the American Society of Hematology 111 (12), 5712-5720, 2008
562008
System-wide identification and prioritization of enzyme substrates by thermal analysis
AA Saei, CM Beusch, P Sabatier, JA Wells, H Gharibi, Z Meng, ...
Nature communications 12 (1), 1296, 2021
552021
Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding
CP Johnson, M Gaetani, V Ortiz, N Bhasin, S Harper, PG Gallagher, ...
Blood 109 (8), 3538-3543, 2007
482007
AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome
M Gaetani, V Matafora, M Saare, D Spiliotopoulos, L Mollica, G Quilici, ...
Nucleic acids research 40 (22), 11756-11768, 2012
452012
Nephrocystin-1 forms a complex with polycystin-1 via a polyproline motif/SH3 domain interaction and regulates the apoptotic response in mammals
C Wodarczyk, G Distefano, I Rowe, M Gaetani, B Bricoli, M Muorah, ...
PloS one 5 (9), e12719, 2010
382010
Capillary leakage provides nutrients and antioxidants for rapid pneumococcal proliferation in influenza-infected lower airways
V Sender, K Hentrich, A Pathak, A Tan Qian Ler, BT Embaie, ...
Proceedings of the National Academy of Sciences 117 (49), 31386-31397, 2020
302020
An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation
P Sabatier, CM Beusch, AA Saei, M Aoun, N Moruzzi, A Coelho, N Leijten, ...
Nature communications 12 (1), 6558, 2021
292021
Unbiased and quantitative proteomics reveals highly increased angiogenesis induction by the secretome of mesenchymal stromal cells isolated from fetal rather than adult skin
M Gaetani, CM Chinnici, AP Carreca, C Di Pasquale, G Amico, ...
Journal of Tissue Engineering and Regenerative Medicine 12 (2), e949-e961, 2018
292018
The common hereditary elliptocytosis-associated α-spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation
SL Harper, S Sriswasdi, HY Tang, M Gaetani, PG Gallagher, DW Speicher
Blood, The Journal of the American Society of Hematology 122 (17), 3045-3053, 2013
282013
The antimicrobial drug pyrimethamine inhibits STAT3 transcriptional activity by targeting the enzyme dihydrofolate reductase
LN Heppler, S Attarha, R Persaud, JI Brown, P Wang, B Petrova, I Tošić, ...
Journal of Biological Chemistry 298 (2), 2022
222022
Thermal proteome profiling identifies oxidative-dependent inhibition of the transcription of major oncogenes as a new therapeutic mechanism for select anticancer compounds
S Peuget, J Zhu, G Sanz, M Singh, M Gaetani, X Chen, Y Shi, AA Saei, ...
Cancer research 80 (7), 1538-1550, 2020
182020
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