| Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation GL Brien, G Gambero, DJ O'connell, E Jerman, SA Turner, CM Egan, ... Nature structural & molecular biology 19 (12), 1273-1281, 2012 | 283 | 2012 |
| Phage versus Phagemid Libraries for Generation of Human Monoclonal Antibodies D O'Connell, B Becerril, A Roy-Burman, M Daws, JD Marks Journal of molecular biology 321 (1), 49-56, 2002 | 204 | 2002 |
| CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression CM Egan, U Nyman, J Skotte, G Streubel, S Turner, DJ O’Connell, ... Developmental cell 26 (3), 223-236, 2013 | 146 | 2013 |
| Complement component C3 is highly expressed in human pancreatic islets and prevents β cell death via ATG16L1 interaction and autophagy regulation BC King, K Kulak, U Krus, R Rosberg, E Golec, K Wozniak, MF Gomez, ... Cell Metabolism 29 (1), 202-210. e6, 2019 | 125 | 2019 |
| A role for the integrin αvβ8 in the negative regulation of epithelial cell growth S Cambier, D Mu, D O’Connell, K Boylen, W Travis, W Liu, VC Broaddus, ... Cancer research 60 (24), 7084-7093, 2000 | 115 | 2000 |
| Transferrin coated nanoparticles: study of the bionano interface in human plasma AS Pitek, D O’Connell, E Mahon, MP Monopoli, F Baldelli Bombelli, ... PloS one 7 (7), e40685, 2012 | 107 | 2012 |
| CX3CL1 is up-regulated in the rat hippocampus during memory-associated synaptic plasticity GK Sheridan, A Wdowicz, M Pickering, O Watters, P Halley, NC O’Sullivan, ... Frontiers in cellular neuroscience 8, 233, 2014 | 86 | 2014 |
| Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients FI Staquicini, M Cardó-Vila, MG Kolonin, M Trepel, JK Edwards, ... Proceedings of the National Academy of Sciences 108 (46), 18637-18642, 2011 | 86 | 2011 |
| Calmodulin binding to the polybasic C-termini of STIM proteins involved in store-operated calcium entry MC Bauer, D O’Connell, DJ Cahill, S Linse Biochemistry 47 (23), 6089-6091, 2008 | 86 | 2008 |
| COTI-2 reactivates mutant p53 and inhibits growth of triple-negative breast cancer cells NC Synnott, D O’connell, J Crown, MJ Duffy Breast Cancer Research and Treatment 179, 47-56, 2020 | 80 | 2020 |
| Characterization of the bionano interface and mapping extrinsic interactions of the corona of nanomaterials DJ O'connell, FB Bombelli, AS Pitek, MP Monopoli, DJ Cahill, KA Dawson Nanoscale 7 (37), 15268-15276, 2015 | 61 | 2015 |
| Direct high affinity interaction between Aβ42 and GSK3α stimulates hyperphosphorylation of tau. A new molecular link in Alzheimer’s disease? CJ Dunning, G McGauran, K Willén, GK Gouras, DJ O’Connell, S Linse ACS chemical neuroscience 7 (2), 161-170, 2016 | 60 | 2016 |
| Sorcin links calcium signaling to vesicle trafficking, regulates Polo-like kinase 1 and is necessary for mitosis VS Lalioti, A Ilari, DJ O'Connell, E Poser, IV Sandoval, G Colotti PloS one 9 (1), e85438, 2014 | 53 | 2014 |
| Identification of a high-affinity network of secretagogin-binding proteins involved in vesicle secretion MC Bauer, DJ O'Connell, M Maj, L Wagner, DJ Cahill, S Linse Molecular BioSystems 7 (7), 2196-2204, 2011 | 51 | 2011 |
| Integrated protein array screening and high throughput validation of 70 novel neural calmodulin-binding proteins DJ O'Connell, MC Bauer, J O'Brien, WM Johnson, CA Divizio, SL O'Kane, ... Molecular & cellular proteomics 9 (6), 1118-1132, 2010 | 49 | 2010 |
| A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence GL Brien, E Healy, E Jerman, E Conway, E Fadda, D O'Donovan, ... Genes & development 29 (21), 2231-2243, 2015 | 41 | 2015 |
| Proteomic analysis and discovery using affinity proteomics and mass spectrometry N Olsson, C Wingren, M Mattsson, P James, D O'Connell, F Nilsson, ... Molecular & Cellular Proteomics 10 (10), 2011 | 40 | 2011 |
| Creation of recombinant antigen-binding molecules derived from hybridomas secreting specific antibodies C Fields, D O'connell, S Xiao, GU Lee, P Billiald, J Muzard Nature protocols 8 (6), 1125-1148, 2013 | 39 | 2013 |
| A microfluidic platform for real-time detection and quantification of protein-ligand interactions TW Herling, DJ O’Connell, MC Bauer, J Persson, U Weininger, ... Biophysical journal 110 (9), 1957-1966, 2016 | 36 | 2016 |
| Epitope presentation is an important determinant of the utility of antigens identified from protein arrays in the development of autoantibody diagnostic assays MA Murphy, DJ O'Connell, SL O'Kane, JK O'Brien, S O'Toole, C Martin, ... Journal of proteomics 75 (15), 4668-4675, 2012 | 28 | 2012 |