Direct charging of tRNACUA with pyrrolysine in vitro and in vivo SK Blight, RC Larue, A Mahapatra, DG Longstaff, E Chang, G Zhao, ... Nature 431 (7006), 333-335, 2004 | 320 | 2004 |
Novel microbial diversity adherent to plant biomass in the herbivore gastrointestinal tract, as revealed by ribosomal intergenic spacer analysis and rrs gene … R Larue, Z Yu, VA Parisi, AR Egan, M Morrison Environmental microbiology 7 (4), 530-543, 2005 | 234 | 2005 |
BET proteins promote efficient murine leukemia virus integration at transcription start sites A Sharma, RC Larue, MR Plumb, N Malani, F Male, A Slaughter, JJ Kessl, ... Proceedings of the National Academy of Sciences 110 (29), 12036-12041, 2013 | 211 | 2013 |
Molecular mechanisms of retroviral integration site selection M Kvaratskhelia, A Sharma, RC Larue, E Serrao, A Engelman Nucleic acids research 42 (16), 10209-10225, 2014 | 155 | 2014 |
HIV-1 integrase binds the viral RNA genome and is essential during virion morphogenesis JJ Kessl, SB Kutluay, D Townsend, S Rebensburg, A Slaughter, RC Larue, ... Cell 166 (5), 1257-1268. e12, 2016 | 154 | 2016 |
A natural genetic code expansion cassette enables transmissible biosynthesis and genetic encoding of pyrrolysine DG Longstaff, RC Larue, JE Faust, A Mahapatra, L Zhang, ... Proceedings of the National Academy of Sciences 104 (3), 1021-1026, 2007 | 115 | 2007 |
The A128T resistance mutation reveals aberrant protein multimerization as the primary mechanism of action of allosteric HIV-1 integrase inhibitors L Feng, A Sharma, A Slaughter, N Jena, Y Koh, N Shkriabai, RC Larue, ... Journal of Biological Chemistry 288 (22), 15813-15820, 2013 | 110 | 2013 |
Rationally designed ACE2-derived peptides inhibit SARS-CoV-2 RC Larue, E Xing, AD Kenney, Y Zhang, JA Tuazon, J Li, JS Yount, PK Li, ... Bioconjugate chemistry 32 (1), 215-223, 2020 | 85 | 2020 |
Structure of the Brd4 ET domain bound to a C-terminal motif from γ-retroviral integrases reveals a conserved mechanism of interaction BL Crowe, RC Larue, C Yuan, S Hess, M Kvaratskhelia, MP Foster Proceedings of the National Academy of Sciences 113 (8), 2086-2091, 2016 | 85 | 2016 |
Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction S Aiyer, GVT Swapna, N Malani, JM Aramini, WM Schneider, MR Plumb, ... Nucleic acids research 42 (9), 5917-5928, 2014 | 78 | 2014 |
Interaction of the HIV-1 intasome with transportin 3 protein (TNPO3 or TRN-SR2) R Larue, K Gupta, C Wuensch, N Shkriabai, JJ Kessl, E Danhart, L Feng, ... Journal of Biological Chemistry 287 (41), 34044-34058, 2012 | 68 | 2012 |
Characterization of a Methanosarcina acetivorans mutant unable to translate UAG as pyrrolysine A Mahapatra, A Patel, JA Soares, RC Larue, JK Zhang, WW Metcalf, ... Molecular microbiology 59 (1), 56-66, 2006 | 63 | 2006 |
Sec24C is an HIV-1 host dependency factor crucial for virus replication SV Rebensburg, G Wei, RC Larue, J Lindenberger, AC Francis, ... Nature microbiology 6 (4), 435-444, 2021 | 58 | 2021 |
The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase A Slaughter, KA Jurado, N Deng, L Feng, JJ Kessl, N Shkriabai, RC Larue, ... Retrovirology 11, 1-14, 2014 | 51 | 2014 |
Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes RC Larue, MR Plumb, BL Crowe, N Shkriabai, A Sharma, J DiFiore, ... Nucleic acids research 42 (8), 4868-4881, 2014 | 48 | 2014 |
HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors PC Koneru, AC Francis, N Deng, SV Rebensburg, AC Hoyte, ... Elife 8, e46344, 2019 | 45 | 2019 |
HIV-1 integrase multimerization as a therapeutic target L Feng, RC Larue, A Slaughter, JJ Kessl, M Kvaratskhelia The Future of HIV-1 Therapeutics: Resistance Is Futile?, 93-119, 2015 | 44 | 2015 |
A critical role of the C-terminal segment for allosteric inhibitor-induced aberrant multimerization of HIV-1 integrase N Shkriabai, V Dharmarajan, A Slaughter, JJ Kessl, RC Larue, L Feng, ... Journal of Biological Chemistry 289 (38), 26430-26440, 2014 | 43 | 2014 |
The competitive interplay between allosteric HIV-1 integrase inhibitor BI/D and LEDGF/p75 during the early stage of HIV-1 replication adversely affects inhibitor potency L Feng, V Dharmarajan, E Serrao, A Hoyte, RC Larue, A Slaughter, ... ACS chemical biology 11 (5), 1313-1321, 2016 | 42 | 2016 |
Structure of Desulfitobacterium hafniense PylSc, a pyrrolysyl-tRNA synthetase MM Lee, R Jiang, R Jain, RC Larue, J Krzycki, MK Chan Biochemical and biophysical research communications 374 (3), 470-474, 2008 | 38 | 2008 |