| Transcriptional regulation of antiviral interferon-stimulated genes W Wang, L Xu, J Su, MP Peppelenbosch, Q Pan Trends in microbiology 25 (7), 573-584, 2017 | 205 | 2017 |
| Modeling rotavirus infection and antiviral therapy using primary intestinal organoids Y Yin, M Bijvelds, W Dang, L Xu, AA van der Eijk, K Knipping, N Tuysuz, ... Antiviral research 123, 120-131, 2015 | 199 | 2015 |
| Hepatitis E virus infects neurons and brains X Zhou, F Huang, L Xu, Z Lin, FMS de Vrij, AC Ayo-Martin, ... The Journal of infectious diseases 215 (8), 1197-1206, 2017 | 129 | 2017 |
| RIG‐I is a key antiviral interferon‐stimulated gene against hepatitis E virus regardless of interferon production L Xu, W Wang, Y Li, X Zhou, Y Yin, Y Wang, RA de Man, ... Hepatology 65 (6), 1823-1839, 2017 | 98 | 2017 |
| Unphosphorylated ISGF3 drives constitutive expression of interferon-stimulated genes to protect against viral infections W Wang, Y Yin, L Xu, J Su, F Huang, Y Wang, PPC Boor, K Chen, ... Science signaling 10 (476), eaah4248, 2017 | 95 | 2017 |
| Cross talk between nucleotide synthesis pathways with cellular immunity in constraining hepatitis E virus replication Y Wang, W Wang, L Xu, X Zhou, E Shokrollahi, K Felczak, ... Antimicrobial agents and chemotherapy 60 (5), 2834-2848, 2016 | 85 | 2016 |
| Convergent Transcription of Interferon-stimulated Genes by TNF-α and IFN-α Augments Antiviral Activity against HCV and HEV W Wang, L Xu, JH Brandsma, Y Wang, MS Hakim, X Zhou, Y Yin, ... Scientific reports 6 (1), 25482, 2016 | 79 | 2016 |
| IFN regulatory factor 1 restricts hepatitis E virus replication by activating STAT1 to induce antiviral IFN‐stimulated genes L Xu, X Zhou, W Wang, Y Wang, Y Yin, LJW van der Laan, D Sprengers, ... The FASEB Journal 30 (10), 3352-3367, 2016 | 68 | 2016 |
| Contact-independent killing mediated by a T6SS effector with intrinsic cell-entry properties L Song, J Pan, Y Yang, Z Zhang, R Cui, S Jia, Z Wang, C Yang, L Xu, ... Nature Communications 12 (1), 423, 2021 | 67 | 2021 |
| PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target Y Yin, W Dang, X Zhou, L Xu, W Wang, W Cao, S Chen, J Su, X Cai, ... Virulence 9 (1), 83-98, 2018 | 65 | 2018 |
| Mycophenolic acid potently inhibits rotavirus infection with a high barrier to resistance development Y Yin, Y Wang, W Dang, L Xu, J Su, X Zhou, W Wang, K Felczak, ... Antiviral research 133, 41-49, 2016 | 64 | 2016 |
| The RNA genome of hepatitis E virus robustly triggers an antiviral interferon response W Wang, Y Wang, C Qu, S Wang, J Zhou, W Cao, L Xu, B Ma, MS Hakim, ... Hepatology 67 (6), 2096-2112, 2018 | 63 | 2018 |
| Nitazoxanide inhibits human norovirus replication and synergizes with ribavirin by activation of cellular antiviral response W Dang, L Xu, B Ma, S Chen, Y Yin, KO Chang, MP Peppelenbosch, ... Antimicrobial agents and chemotherapy 62 (11), 10.1128/aac. 00707-18, 2018 | 60 | 2018 |
| IRF-1, RIG-I and MDA5 display potent antiviral activities against norovirus coordinately induced by different types of interferons W Dang, L Xu, Y Yin, S Chen, W Wang, MS Hakim, KO Chang, ... Antiviral research 155, 48-59, 2018 | 56 | 2018 |
| 6-Thioguanine inhibits rotavirus replication through suppression of Rac1 GDP/GTP cycling Y Yin, S Chen, MS Hakim, W Wang, L Xu, W Dang, C Qu, AP Verhaar, ... Antiviral research 156, 92-101, 2018 | 54 | 2018 |
| Suppression of pyrimidine biosynthesis by targeting DHODH enzyme robustly inhibits rotavirus replication S Chen, S Ding, Y Yin, L Xu, P Li, MP Peppelenbosch, Q Pan, W Wang Antiviral research 167, 35-44, 2019 | 53 | 2019 |
| Blocking Wnt secretion reduces growth of hepatocellular carcinoma cell lines mostly independent of β-catenin signaling W Wang, L Xu, P Liu, K Jairam, Y Yin, K Chen, D Sprengers, ... Neoplasia 18 (12), 711-723, 2016 | 50 | 2016 |
| Disparity of basal and therapeutically activated interferon signalling in constraining hepatitis E virus infection X Zhou, L Xu, W Wang, K Watashi, Y Wang, D Sprengers, PE De Ruiter, ... Journal of viral hepatitis 23 (4), 294-304, 2016 | 50 | 2016 |
| MicroRNA-221-5p inhibits porcine epidemic diarrhea virus replication by targeting genomic viral RNA and activating the NF-κB pathway H Zheng, L Xu, Y Liu, C Li, L Zhang, T Wang, D Zhao, X Xu, Y Zhang International journal of molecular sciences 19 (11), 3381, 2018 | 48 | 2018 |
| T6SS translocates a micropeptide to suppress STING-mediated innate immunity by sequestering manganese L Zhu, L Xu, C Wang, C Li, M Li, Q Liu, X Wang, W Yang, D Pan, L Hu, ... Proceedings of the National Academy of Sciences 118 (42), e2103526118, 2021 | 45 | 2021 |
Dave SprengersDept Gastroenterology and Hepatology, Erasmus MC University Hospital Rotterdam, The NetherlandsVerified email at erasmusmc.nl
