Mechanism of IS200/IS605 family DNA transposases: activation and transposon-directed target site selection O Barabas, DR Ronning, C Guynet, AB Hickman, B Ton-Hoang, ... Cell 132 (2), 208-220, 2008 | 155 | 2008 |
Structural Insights into the Catalytic Mechanism of Phosphate Ester Hydrolysis by dUTPase*♦ O Barabás, V Pongrácz, J Kovári, M Wilmanns, BG Vértessy Journal of Biological Chemistry 279 (41), 42907-42915, 2004 | 116 | 2004 |
Helicobacter pylori's plasticity zones are novel transposable elements D Kersulyte, WK Lee, D Subramaniam, S Anant, P Herrera, L Cabrera, ... PloS one 4 (9), e6859, 2009 | 108 | 2009 |
A highly soluble Sleeping Beauty transposase improves control of gene insertion I Querques, A Mades, C Zuliani, C Miskey, M Alb, E Grueso, M Machwirth, ... Nature biotechnology 37 (12), 1502-1512, 2019 | 97 | 2019 |
Active site closure facilitates juxtaposition of reactant atoms for initiation of catalysis by human dUTPase B Varga, O Barabás, J Kovári, J Tóth, É Hunyadi-Gulyás, É Klement, ... FEBS letters 581 (24), 4783-4788, 2007 | 94 | 2007 |
Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor B Varga, O Barabás, E Takács, N Nagy, P Nagy, BG Vértessy Biochemical and biophysical research communications 373 (1), 8-13, 2008 | 84 | 2008 |
Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes S Khedkar, G Smyshlyaev, I Letunic, OM Maistrenko, LP Coelho, ... Nucleic Acids Research 50 (6), 3155-3168, 2022 | 74 | 2022 |
Crystal structure of the primary piRNA biogenesis factor Zucchini reveals similarity to the bacterial PLD endonuclease Nuc F Voigt, M Reuter, A Kasaruho, EC Schulz, RS Pillai, O Barabas Rna 18 (12), 2128-2134, 2012 | 71 | 2012 |
In vitro reconstitution of a single-stranded transposition mechanism of IS608 C Guynet, AB Hickman, O Barabas, F Dyda, M Chandler, B Ton-Hoang Molecular cell 29 (3), 302-312, 2008 | 71 | 2008 |
An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum T Bock, WH Chen, A Ori, N Malik, N Silva-Martin, J Huerta-Cepas, ... Nucleic acids research 42 (22), 13525-13533, 2014 | 69 | 2014 |
Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins V Nemeth-Pongracz, O Barabas, M Fuxreiter, I Simon, I Pichová, ... Nucleic acids research 35 (2), 495-505, 2007 | 65 | 2007 |
Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric … J Kovári, O Barabás, E Takács, A Békési, Z Dubrovay, V Pongrácz, ... Journal of Biological Chemistry 279 (17), 17932-17944, 2004 | 65 | 2004 |
Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering F Voigt, L Wiedemann, C Zuliani, I Querques, A Sebe, L Mátés, Z Izsvák, ... Nature communications 7 (1), 1-8, 2016 | 64 | 2016 |
Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r J Kardos, V Harmat, A Palló, O Barabás, K Szilágyi, L Gráf, ... Molecular immunology 45 (6), 1752-1760, 2008 | 55 | 2008 |
Transposase-DNA complex structures reveal mechanisms for conjugative transposition of antibiotic resistance A Rubio-Cosials, EC Schulz, L Lambertsen, G Smyshlyaev, ... Cell 173 (1), 208-220. e20, 2018 | 50 | 2018 |
Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes G Smyshlyaev, A Bateman, O Barabas Molecular systems biology 17 (5), e9880, 2021 | 49 | 2021 |
DNA recognition and the precleavage state during single‐stranded DNA transposition in D. radiodurans AB Hickman, JA James, O Barabas, C Pasternak, B Ton‐Hoang, ... The EMBO journal 29 (22), 3840-3852, 2010 | 48 | 2010 |
The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans C Weng, J Kosalka, AC Berkyurek, P Stempor, X Feng, H Mao, C Zeng, ... Genes & development 33 (1-2), 90-102, 2019 | 44 | 2019 |
The USTC complex co-opts an ancient machinery to drive piRNA transcription in C. elegans C Weng, A Kosalka, AC Berkyurek, P Stempor, X Feng, H Mao, C Zeng, ... BioRxiv, 377390, 2018 | 44* | 2018 |
Methylene substitution at the α–β bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site J Kovari, O Barabás, B Varga, A Békési, F Tölgyesi, J Fidy, J Nagy, ... Proteins: Structure, Function, and Bioinformatics 71 (1), 308-319, 2008 | 44 | 2008 |