| Predicting functionally important residues from sequence conservation JA Capra, M Singh Bioinformatics 23 (15), 1875-1882, 2007 | 775 | 2007 |
| Dynamic and Coordinated Epigenetic Regulation of Developmental Transitions in the Cardiac Lineage JA Wamstad, JM Alexander, RM Truty, A Shrikumar, F Li, KE Eilertson, ... Cell, 2012 | 671 | 2012 |
| DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase K Paeschke, JA Capra, VA Zakian Cell 145 (5), 678-691, 2011 | 614 | 2011 |
| Predicting protein ligand binding sites by combining evolutionary sequence conservation and 3D structure JA Capra, RA Laskowski, JM Thornton, M Singh, TA Funkhouser PLoS computational biology 5 (12), e1000585, 2009 | 492 | 2009 |
| The phenotypic legacy of admixture between modern humans and Neandertals CN Simonti, B Vernot, L Bastarache, E Bottinger, DS Carrell, RL Chisholm, ... Science 351 (6274), 737-741, 2016 | 369 | 2016 |
| G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae JA Capra, K Paeschke, M Singh, VA Zakian PLoS computational biology 6 (7), e1000861, 2010 | 326 | 2010 |
| SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion KA Anderson, FK Huynh, K Fisher-Wellman, JD Stuart, BS Peterson, ... Cell metabolism 25 (4), 838-855. e15, 2017 | 312 | 2017 |
| Many human accelerated regions are developmental enhancers JA Capra, GD Erwin, G McKinsey, JLR Rubenstein, KS Pollard Philosophical Transactions of the Royal Society B: Biological Sciences 368 …, 2013 | 254 | 2013 |
| Folding and misfolding of human membrane proteins in health and disease: from single molecules to cellular proteostasis JT Marinko, H Huang, WD Penn, JA Capra, JP Schlebach, CR Sanders Chemical reviews 119 (9), 5537-5606, 2019 | 228 | 2019 |
| The influence of evolutionary history on human health and disease ML Benton, A Abraham, AL LaBella, P Abbot, A Rokas, JA Capra Nature Reviews Genetics 22 (5), 269-283, 2021 | 227 | 2021 |
| Integrating diverse datasets improves developmental enhancer prediction GD Erwin, RM Truty, D Kostka, KS Pollard, JA Capra PLoS Computational Biology 10 (6), e1003677, 2013 | 188 | 2013 |
| Topologically associating domain boundaries that are stable across diverse cell types are evolutionarily constrained and enriched for heritability E McArthur, JA Capra The American Journal of Human Genetics 108 (2), 269-283, 2021 | 165 | 2021 |
| Joint mouse–human phenome-wide association to test gene function and disease risk X Wang, AK Pandey, MK Mulligan, EG Williams, K Mozhui, Z Li, ... Nature communications 7 (1), 10464, 2016 | 156 | 2016 |
| The mouse brain library@ www. mbl. org GD Rosen, AG Williams, JA Capra, MT Connolly, B Cruz, L Lu, DC Airey, ... Int Mouse Genome Conference 14 (166), 2000 | 146 | 2000 |
| Acetylation of RNA polymerase II regulates growth-factor-induced gene transcription in mammalian cells S Schröder, E Herker, F Itzen, D He, S Thomas, DA Gilchrist, K Kaehlcke, ... Molecular cell 52 (3), 314-324, 2013 | 140 | 2013 |
| Characterization and prediction of residues determining protein functional specificity JA Capra, M Singh Bioinformatics 24 (13), 1473-1480, 2008 | 134 | 2008 |
| XPA: A key scaffold for human nucleotide excision repair N Sugitani, RM Sivley, KE Perry, JA Capra, WJ Chazin DNA repair 44, 123-135, 2016 | 130 | 2016 |
| SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1, 2 and HMGCS1, 2 MD Hirschey, T Shimazu, JA Capra, KS Pollard, E Verdin Aging (Albany NY) 3 (6), 635, 2011 | 128 | 2011 |
| High-throughput reclassification of SCN5A variants AM Glazer, Y Wada, B Li, A Muhammad, OR Kalash, MJ O’Neill, T Shields, ... The American Journal of Human Genetics 107 (1), 111-123, 2020 | 121 | 2020 |
| Predicting changes in protein thermodynamic stability upon point mutation with deep 3D convolutional neural networks B Li, YT Yang, JA Capra, MB Gerstein PLoS computational biology 16 (11), e1008291, 2020 | 117 | 2020 |