| Amyloid β-Peptide Oligomers Stimulate RyR-Mediated Ca2+ Release Inducing Mitochondrial Fragmentation in Hippocampal Neurons and Prevent RyR-Mediated … AC Paula-Lima, T Adasme, C SanMartin, A Sebollela, C Hetz, ... Antioxidants & redox signaling 14 (7), 1209-1223, 2011 | 169 | 2011 |
| Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation T Adasme, P Haeger, AC Paula-Lima, I Espinoza, MM Casas-Alarcón, ... Proceedings of the National Academy of Sciences 108 (7), 3029-3034, 2011 | 156 | 2011 |
| Contribution of Ca2+ Release Channels to Hippocampal Synaptic Plasticity and Spatial Memory: Potential Redox Modulation AC Paula-Lima, T Adasme, C Hidalgo Antioxidants & redox signaling 21 (6), 892-914, 2014 | 77 | 2014 |
| Aging impairs hippocampal-dependent recognition memory and LTP and prevents the associated RyR up-regulation A Arias-Cavieres, T Adasme, G Sánchez, P Muñoz, C Hidalgo Frontiers in aging neuroscience 9, 111, 2017 | 73 | 2017 |
| Astaxanthin Protects Primary Hippocampal Neurons against Noxious Effects of Aβ‐Oligomers P Lobos, B Bruna, A Cordova, P Barattini, JL Galáz, T Adasme, C Hidalgo, ... Neural Plasticity 2016 (1), 3456783, 2016 | 72 | 2016 |
| The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling JP Muñoz, A Collao, M Chiong, C Maldonado, T Adasme, L Carrasco, ... Biochemical and biophysical research communications 388 (1), 155-160, 2009 | 69 | 2009 |
| High-frequency field stimulation of primary neurons enhances ryanodine receptor-mediated Ca2+ release and generates hydrogen peroxide, which jointly stimulate NF-κB activity D Riquelme, A Alvarez, N Leal, T Adasme, I Espinoza, JA Valdés, ... Antioxidants & redox signaling 14 (7), 1245-1259, 2011 | 62 | 2011 |
| The signaling pathways underlying BDNF-induced Nrf2 hippocampal nuclear translocation involve ROS, RyR-Mediated Ca2+ signals, ERK and PI3K B Bruna, P Lobos, R Herrera-Molina, C Hidalgo, A Paula-Lima, T Adasme Biochemical and biophysical research communications 505 (1), 201-207, 2018 | 60 | 2018 |
| Calcium release mediated by redox-sensitive RyR2 channels has a central role in hippocampal structural plasticity and spatial memory JY More, BA Bruna, PE Lobos, JL Galaz, PL Figueroa, S Namias, ... Antioxidants & Redox Signaling 29 (12), 1125-1146, 2018 | 52 | 2018 |
| RyR2-Mediated Ca2+ Release and Mitochondrial ROS Generation Partake in the Synaptic Dysfunction Caused by Amyloid β Peptide Oligomers CD SanMartín, P Veloso, T Adasme, P Lobos, B Bruna, J Galaz, A García, ... Frontiers in Molecular Neuroscience 10, 115, 2017 | 52 | 2017 |
| IGF-1 protects cardiac myocytes from hyperosmotic stress-induced apoptosis via CREB C Maldonado, P Cea, T Adasme, A Collao, G Díaz-Araya, M Chiong, ... Biochemical and biophysical research communications 336 (4), 1112-1118, 2005 | 47 | 2005 |
| The antioxidant N-acetylcysteine prevents the mitochondrial fragmentation induced by soluble amyloid-F peptide oligomers CD Sanmartin, T Adasme, C Hidalgo, AC Paula-Lima Neurodegenerative Diseases 10 (1-4), 34-37, 2012 | 42 | 2012 |
| Inhibitory ryanodine prevents ryanodine receptor-mediated Ca2+ release without affecting endoplasmic reticulum Ca2+ content in primary hippocampal neurons T Adasme, A Paula-Lima, C Hidalgo Biochemical and biophysical research communications 458 (1), 57-62, 2015 | 33 | 2015 |
| RyR-mediated Ca2+ release elicited by neuronal activity induces nuclear Ca2+ signals, CREB phosphorylation, and Npas4/RyR2 expression P Lobos, A Córdova, I Vega-Vásquez, OA Ramírez, T Adasme, J Toledo, ... Proceedings of the National Academy of Sciences 118 (33), e2102265118, 2021 | 30 | 2021 |
| Increased hippocampal expression of the divalent metal transporter 1 (DMT1) mRNA variants 1B and+ IRE and DMT1 protein after NMDA-receptor stimulation or spatial memory training P Haeger, A Alvarez, N Leal, T Adasme, MT Núnez, C Hidalgo Neurotoxicity research 17, 238-247, 2010 | 28 | 2010 |
| Development of an iron-selective antioxidant probe with protective effects on neuronal function O García-Beltrán, NP Mena, P Aguirre, G Barriga-Gonzalez, A Galdámez, ... PloS one 12 (12), e0189043, 2017 | 22 | 2017 |
| Triclosan impairs hippocampal synaptic plasticity and spatial memory in male rats A Arias-Cavieres, J More, JM Vicente, T Adasme, J Hidalgo, JL Valdés, ... Frontiers in Molecular Neuroscience 11, 429, 2018 | 21 | 2018 |
| Astaxanthin counteracts excitotoxicity and reduces the ensuing increases in calcium levels and mitochondrial reactive oxygen species generation F García, P Lobos, A Ponce, K Cataldo, D Meza, P Farías, C Estay, ... Marine Drugs 18 (6), 335, 2020 | 20 | 2020 |
| Accelerating medicines partnership® Schizophrenia (AMP® SCZ): Rationale and study design of the largest global prospective cohort study of clinical high risk for psychosis CMJ Wannan, B Nelson, J Addington, K Allott, A Anticevic, C Arango, ... Schizophrenia Bulletin 50 (3), 496-512, 2024 | 9 | 2024 |
| Long-term potentiation and spatial memory training stimulate the hippocampal expression of RyR2 calcium release channels I Valdés-Undurraga, P Lobos, V Sánchez-Robledo, A Arias-Cavieres, ... Frontiers in Cellular Neuroscience 17, 1132121, 2023 | 8 | 2023 |
Cecilia HidalgoDept. Neurosciences, BNI, CEMC, ICBM, F. Medicine, Universidad de ChileVerified email at med.uchile.cl