| A Role for the Unfolded Protein Response (UPR) in Virulence and Antifungal Susceptibility in Aspergillus fumigatus DL Richie, L Hartl, V Aimanianda, MS Winters, KK Fuller, MD Miley, ... PLoS pathogens 5 (1), e1000258, 2009 | 190 | 2009 |
| Unexpected Link between Metal Ion Deficiency and Autophagy in Aspergillus fumigatus DL Richie, KK Fuller, J Fortwendel, MD Miley, JW McCarthy, ... Eukaryotic cell 6 (12), 2437-2447, 2007 | 139 | 2007 |
| HacA-Independent Functions of the ER Stress Sensor IreA Synergize with the Canonical UPR to Influence Virulence Traits in Aspergillus fumigatus X Feng, K Krishnan, DL Richie, V Aimanianda, L Hartl, N Grahl, ... PLoS pathogens 7 (10), e1002330, 2011 | 119 | 2011 |
| The Aspergillus fumigatus metacaspases CasA and CasB facilitate growth under conditions of endoplasmic reticulum stress DL Richie, MD Miley, R Bhabhra, GD Robson, JC Rhodes, DS Askew Molecular microbiology 63 (2), 591-604, 2007 | 109 | 2007 |
| Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid … J Bojkovic, DL Richie, DA Six, CM Rath, WS Sawyer, Q Hu, CR Dean Journal of bacteriology 198 (4), 731-741, 2016 | 80 | 2016 |
| Divergent Protein Kinase A isoforms co‐ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus KK Fuller, DL Richie, X Feng, K Krishnan, TJ Stephens, ... Molecular microbiology 79 (4), 1045-1062, 2011 | 70 | 2011 |
| Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents DL Richie, KV Thompson, C Studer, VC Prindle, T Aust, R Riedl, ... Antimicrobial agents and chemotherapy 57 (5), 2272-2280, 2013 | 56 | 2013 |
| The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation … DL Richie, X Feng, L Hartl, V Aimanianda, K Krishnan, ... Virulence 2 (1), 12-21, 2011 | 50* | 2011 |
| Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606 DL Richie, KT Takeoka, J Bojkovic, LE Metzger IV, CM Rath, WS Sawyer, ... PloS one 11 (8), e0160918, 2016 | 33 | 2016 |
| An integrated approach for identification and target validation of antifungal compounds active against Erg11p D Hoepfner, S Karkare, SB Helliwell, M Pfeifer, M Trunzer, ... Antimicrobial agents and chemotherapy 56 (8), 4233-4240, 2012 | 33 | 2012 |
| Synthesis of ciprofloxacin dimers for evaluation of bacterial permeability in atypical chemical space AG Ross, BM Benton, D Chin, G De Pascale, J Fuller, JA Leeds, F Reck, ... Bioorganic & medicinal chemistry letters 25 (17), 3468-3475, 2015 | 30 | 2015 |
| Effects of a defective endoplasmic reticulum-associated degradation pathway on the stress response, virulence, and antifungal drug susceptibility of the mold pathogen … K Krishnan, X Feng, MV Powers-Fletcher, G Bick, DL Richie, LA Woollett, ... Eukaryotic cell 12 (4), 512-519, 2013 | 30 | 2013 |
| Nonspecific effect of Mycograb on amphotericin B MIC DL Richie, MA Ghannoum, N Isham, KV Thompson, NS Ryder Antimicrobial agents and chemotherapy 56 (7), 3963-3964, 2012 | 30 | 2012 |
| Topoisomerase inhibitors addressing fluoroquinolone resistance in Gram-negative bacteria CK Skepper, D Armstrong, CJ Balibar, D Bauer, C Bellamacina, ... Journal of Medicinal Chemistry 63 (14), 7773-7816, 2020 | 25 | 2020 |
| Interplay of Klebsiella pneumoniae fabZ and lpxC Mutations Leads to LpxC Inhibitor-Dependent Growth Resulting from Loss of Membrane Homeostasis M Mostafavi, L Wang, L Xie, KT Takeoka, DL Richie, F Casey, A Ruzin, ... Msphere 3 (5), 10.1128/msphere. 00508-18, 2018 | 25 | 2018 |
| LpxK is essential for growth of Acinetobacter baumannii ATCC 19606: relationship to toxic accumulation of lipid A pathway intermediates JR Wei, DL Richie, M Mostafavi, LE Metzger IV, CM Rath, WS Sawyer, ... MSphere 2 (4), 10.1128/msphere. 00199-17, 2017 | 23* | 2017 |
| Autophagy: a role in metal ion homeostasis? DL Richie, DS Askew Autophagy 4 (1), 115-117, 2008 | 19 | 2008 |
| Discovery and optimization of DNA gyrase and topoisomerase IV inhibitors with potent activity against fluoroquinolone-resistant gram-positive bacteria G Lapointe, CK Skepper, LM Holder, D Armstrong, C Bellamacina, J Blais, ... Journal of Medicinal Chemistry 64 (9), 6329-6357, 2021 | 17 | 2021 |
| Impaired Ribosome Biogenesis Disrupts the Integration between Morphogenesis and Nuclear Duplication during the Germination of Aspergillus fumigatus R Bhabhra, DL Richie, HS Kim, WC Nierman, J Fortwendel, JP Aris, ... Eukaryotic Cell 7 (4), 575-583, 2008 | 16 | 2008 |
| Autophagy in the filamentous fungus Aspergillus fumigatus DL Richie, DS Askew Methods in enzymology 451, 241-250, 2008 | 16 | 2008 |
Karthik Mosur KrishnanFood and Drug Administration