A method and server for predicting damaging missense mutations IA Adzhubei, S Schmidt, L Peshkin, VE Ramensky, A Gerasimova, P Bork, ... Nature methods 7 (4), 248-249, 2010 | 14547 | 2010 |
STRING: a database of predicted functional associations between proteins C Mering, M Huynen, D Jaeggi, S Schmidt, P Bork, B Snel Nucleic acids research 31 (1), 258-261, 2003 | 2623 | 2003 |
SMART 4.0: towards genomic data integration I Letunic, RR Copley, S Schmidt, FD Ciccarelli, T Doerks, J Schultz, ... Nucleic Acids Research 32 (suppl 1), D142-D144, 2004 | 1204 | 2004 |
Assessing the evolutionary impact of amino acid mutations in the human genome AR Boyko, SH Williamson, AR Indap, JD Degenhardt, RD Hernandez, ... PLoS Genet 4 (5), e1000083, 2008 | 698 | 2008 |
Proportionally more deleterious genetic variation in European than in African populations KE Lohmueller, AR Indap, S Schmidt, AR Boyko, RD Hernandez, ... Nature 451 (7181), 994-997, 2008 | 461 | 2008 |
ProtGPT2 is a deep unsupervised language model for protein design N Ferruz, S Schmidt, B Höcker Nature communications 13 (1), 1-10, 2022 | 446 | 2022 |
Active Alu retrotransposons in the human genome EA Bennett, H Keller, RE Mills, S Schmidt, JV Moran, O Weichenrieder, ... Genome research 18 (12), 1875-1883, 2008 | 337 | 2008 |
Medical sequencing at the extremes of human body mass N Ahituv, N Kavaslar, W Schackwitz, A Ustaszewska, J Martin, S Hébert, ... The American Journal of Human Genetics 80 (4), 779-791, 2007 | 259 | 2007 |
Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival N Wittkopp, E Huntzinger, C Weiler, J Saulière, S Schmidt, M Sonawane, ... Molecular and cellular biology 29 (13), 3517-3528, 2009 | 227 | 2009 |
Small RNA binding to the lateral surface of Hfq hexamers and structural rearrangements upon mRNA target recognition E Sauer, S Schmidt, O Weichenrieder Proceedings of the National Academy of Sciences 109 (24), 9396-9401, 2012 | 192 | 2012 |
Metabolites: a helping hand for pathway evolution? S Schmidt, S Sunyaev, P Bork, T Dandekar Trends in Biochemical Sciences 28 (6), 336-341, 2003 | 189 | 2003 |
Trimeric structure and flexibility of the L1ORF1 protein in human L1 retrotransposition E Khazina, V Truffault, R Büttner, S Schmidt, M Coles, O Weichenrieder Nature structural & molecular biology 18 (9), 1006-1014, 2011 | 169 | 2011 |
Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein A Boland, E Huntzinger, S Schmidt, E Izaurralde, O Weichenrieder Proceedings of the National Academy of Sciences 108 (26), 10466-10471, 2011 | 169 | 2011 |
Systematic discovery of analogous enzymes in thiamin biosynthesis E Morett, JO Korbel, E Rajan, G Saab-Rincon, L Olvera, M Olvera, ... Nature biotechnology 21 (7), 790-795, 2003 | 166 | 2003 |
A limited role for balancing selection S Asthana, S Schmidt, S Sunyaev TRENDS in Genetics 21 (1), 30-32, 2005 | 164 | 2005 |
The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4–NOT deadenylase complex AP Petit, L Wohlbold, P Bawankar, E Huntzinger, S Schmidt, E Izaurralde, ... Nucleic acids research 40 (21), 11058-11072, 2012 | 147 | 2012 |
NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain P Bawankar, B Loh, L Wohlbold, S Schmidt, E Izaurralde RNA biology 10 (2), 228-244, 2013 | 124 | 2013 |
Small fitness effect of mutations in highly conserved non-coding regions GV Kryukov, S Schmidt, S Sunyaev Human molecular genetics 14 (15), 2221-2229, 2005 | 101 | 2005 |
Two (βα) 8-barrel enzymes of histidine and tryptophan biosynthesis have similar reaction mechanisms and common strategies for protecting their labile substrates M Henn-Sax, R Thoma, S Schmidt, M Hennig, K Kirschner, R Sterner Biochemistry 41 (40), 12032-12042, 2002 | 100 | 2002 |
Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes F Tritschler, A Eulalio, S Helms, S Schmidt, M Coles, O Weichenrieder, ... Molecular and cellular biology 28 (21), 6695-6708, 2008 | 99 | 2008 |