| Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis P Skendros, A Mitsios, A Chrysanthopoulou, DC Mastellos, S Metallidis, ... The Journal of clinical investigation 130 (11), 6151-6157, 2020 | 736 | 2020 |
| Complement as a target in COVID-19? AM Risitano, DC Mastellos, M Huber-Lang, D Yancopoulou, C Garlanda, ... Nature Reviews Immunology 20 (6), 343-344, 2020 | 564 | 2020 |
| A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways K Ritis, M Doumas, D Mastellos, A Micheli, S Giaglis, P Magotti, S Rafail, ... The Journal of Immunology 177 (7), 4794-4802, 2006 | 558 | 2006 |
| Complement component C3–The “Swiss Army Knife” of innate immunity and host defense D Ricklin, ES Reis, DC Mastellos, P Gros, JD Lambris Immunological reviews 274 (1), 33-58, 2016 | 544 | 2016 |
| The proinflammatory mediators C3a and C5a are essential for liver regeneration CW Strey, M Markiewski, D Mastellos, R Tudoran, LA Spruce, ... The Journal of experimental medicine 198 (6), 913-923, 2003 | 523 | 2003 |
| Novel mechanisms and functions of complement G Hajishengallis, ES Reis, DC Mastellos, D Ricklin, JD Lambris Nature immunology 18 (12), 1288-1298, 2017 | 456 | 2017 |
| New insights into the immune functions of complement ES Reis, DC Mastellos, G Hajishengallis, JD Lambris Nature Reviews Immunology 19 (8), 503-516, 2019 | 389 | 2019 |
| Complement in cancer: untangling an intricate relationship ES Reis, DC Mastellos, D Ricklin, A Mantovani, JD Lambris Nature Reviews Immunology 18 (1), 5-18, 2018 | 382 | 2018 |
| The renaissance of complement therapeutics D Ricklin, DC Mastellos, ES Reis, JD Lambris Nature Reviews Nephrology 14 (1), 26-47, 2018 | 376 | 2018 |
| Clinical promise of next-generation complement therapeutics DC Mastellos, D Ricklin, JD Lambris Nature reviews Drug discovery 18 (9), 707-729, 2019 | 310 | 2019 |
| A novel role of complement: mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration D Mastellos, JC Papadimitriou, S Franchini, PA Tsonis, JD Lambris The Journal of Immunology 166 (4), 2479-2486, 2001 | 309 | 2001 |
| The first case of COVID-19 treated with the complement C3 inhibitor AMY-101 S Mastaglio, A Ruggeri, AM Risitano, P Angelillo, D Yancopoulou, ... Clinical immunology 215, 108450, 2020 | 299 | 2020 |
| Increased C5a receptor expression in sepsis NC Riedemann, RF Guo, TA Neff, IJ Laudes, KA Keller, VJ Sarma, ... The Journal of clinical investigation 110 (1), 101-108, 2002 | 298 | 2002 |
| Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1 R Reca, D Mastellos, M Majka, L Marquez, J Ratajczak, S Franchini, ... Blood, The Journal of the American Society of Hematology 101 (10), 3784-3793, 2003 | 272 | 2003 |
| Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy DC Mastellos, BGPP da Silva, BAL Fonseca, NP Fonseca, ... Clinical Immunology 220, 108598, 2020 | 234 | 2020 |
| Compstatin: a C3‐targeted complement inhibitor reaching its prime for bedside intervention DC Mastellos, D Yancopoulou, P Kokkinos, M Huber‐Lang, ... European journal of clinical investigation 45 (4), 423-440, 2015 | 234 | 2015 |
| Protection of innate immunity by C5aR antagonist in septic mice MS Huber‐Lang, NC Riedeman, JV Sarma, EM Younkin, SR McGuire, ... Wiley Periodicals, Inc., 2002 | 220 | 2002 |
| Complement: more than a ‘guard’against invading pathogens? D Mastellos, JD Lambris TRENDS in Immunology 23 (10), 485-491, 2002 | 205 | 2002 |
| C3a and C3b activation products of the third component of complement (C3) are critical for normal liver recovery after toxic injury MM Markiewski, D Mastellos, R Tudoran, RA DeAngelis, CW Strey, ... The Journal of Immunology 173 (2), 747-754, 2004 | 196 | 2004 |
| Phylogenetic aspects of the complement system IK Zarkadis, D Mastellos, JD Lambris Developmental & Comparative Immunology 25 (8-9), 745-762, 2001 | 176 | 2001 |
John D. LambrisUniversity of PennsylvaniaVerified email at lambris.com