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Metastability of native proteins and the phenomenon of amyloid formation AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ... Journal of the American Chemical Society 133 (36), 14160-14163, 2011 | 510 | 2011 |
Cisplatin binding sites on human albumin AI Ivanov, J Christodoulou, JA Parkinson, KJ Barnham, A Tucker, ... Journal of Biological Chemistry 273 (24), 14721-14730, 1998 | 480 | 1998 |
Multi-metal binding site of serum albumin W Bal, J Christodoulou, PJ Sadler, A Tucker Journal of inorganic biochemistry 70 (1), 33-39, 1998 | 407 | 1998 |
Heat shock protein 70 inhibits α-synuclein fibril formation via preferential binding to prefibrillar species MM Dedmon, J Christodoulou, MR Wilson, CM Dobson Journal of Biological Chemistry 280 (15), 14733-14740, 2005 | 302 | 2005 |
Structure and properties of a complex of α-synuclein and a single-domain camelid antibody EJ De Genst, T Guilliams, J Wellens, EM O'day, CA Waudby, S Meehan, ... Journal of molecular biology 402 (2), 326-343, 2010 | 213 | 2010 |
Two-dimensional NMR lineshape analysis CA Waudby, A Ramos, LD Cabrita, J Christodoulou Scientific reports 6 (1), 24826, 2016 | 201 | 2016 |
The interaction of αB-crystallin with mature α-synuclein amyloid fibrils inhibits their elongation CA Waudby, TPJ Knowles, GL Devlin, JN Skepper, H Ecroyd, JA Carver, ... Biophysical journal 98 (5), 843-851, 2010 | 174 | 2010 |
Cytochrome display on amyloid fibrils AJ Baldwin, R Bader, J Christodoulou, CE MacPhee, CM Dobson, ... Journal of the American Chemical Society 128 (7), 2162-2163, 2006 | 173 | 2006 |
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson’s disease G Toth, SJ Gardai, W Zago, CW Bertoncini, N Cremades, SL Roy, ... PloS one 9 (2), e87133, 2014 | 164 | 2014 |
Protein folding on the ribosome LD Cabrita, CM Dobson, J Christodoulou Current opinion in structural biology 20 (1), 33-45, 2010 | 154 | 2010 |
A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction J Gsponer, J Christodoulou, A Cavalli, JM Bui, B Richter, CM Dobson, ... Structure 16 (5), 736-746, 2008 | 152 | 2008 |
A structural ensemble of a ribosome–nascent chain complex during cotranslational protein folding LD Cabrita, AME Cassaignau, HMM Launay, CA Waudby, T Wlodarski, ... Nature structural & molecular biology 23 (4), 278-285, 2016 | 147 | 2016 |
Structure and dynamics of a ribosome-bound nascent chain by NMR spectroscopy STD Hsu, P Fucini, LD Cabrita, H Launay, CM Dobson, J Christodoulou Proceedings of the National Academy of Sciences 104 (42), 16516-16521, 2007 | 144 | 2007 |
Nature and regulation of protein folding on the ribosome CA Waudby, CM Dobson, J Christodoulou Trends in biochemical sciences 44 (11), 914-926, 2019 | 136 | 2019 |
Chaperone proteostasis in Parkinson's disease: Stabilization of the Hsp70/α‐synuclein complex by Hip C Roodveldt, CW Bertoncini, A Andersson, AT Van Der Goot, ST Hsu, ... The EMBO journal 28 (23), 3758-3770, 2009 | 134 | 2009 |
Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages T Guilliams, F El-Turk, AK Buell, EM O'Day, FA Aprile, EK Esbjörner, ... Journal of molecular biology 425 (14), 2397-2411, 2013 | 129 | 2013 |
On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of α-synuclein with Congo red and lacmoid C Lendel, CW Bertoncini, N Cremades, CA Waudby, M Vendruscolo, ... Biochemistry 48 (35), 8322-8334, 2009 | 127 | 2009 |
Molecular determinants of the aggregation behavior of α‐and β‐synuclein RC Rivers, JR Kumita, GG Tartaglia, MM Dedmon, A Pawar, ... Protein Science 17 (5), 887-898, 2008 | 123 | 2008 |
A New Structural Transition of Serum Albumin Dependent on the State of Cys34: Detection by 1H‐NMR Spectroscopy J Christodoulou, PJ Sadler, A Tucker European journal of biochemistry 225 (1), 363-368, 1994 | 122 | 1994 |