| Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)—a study … G Coltro, AA Mangaonkar, TL Lasho, CM Finke, P Pophali, R Carr, ... Leukemia 34 (5), 1407-1421, 2020 | 100 | 2020 |
| RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis RM Carr, D Vorobyev, T Lasho, DL Marks, EJ Tolosa, A Vedder, ... Nature communications 12 (1), 2901, 2021 | 84 | 2021 |
| Pancreatic cancer microenvironment, to target or not to target? RM Carr, ME Fernandez‐Zapico EMBO molecular medicine 8 (2), 80-82, 2016 | 74 | 2016 |
| ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL S Pietrobono, G Anichini, C Sala, F Manetti, LL Almada, S Pepe, RM Carr, ... Nature communications 11 (1), 5865, 2020 | 73 | 2020 |
| Suboptimal response rates to hypomethylating agent therapy in chronic myelomonocytic leukemia; a single institutional study of 121 patients T Coston, P Pophali, R Vallapureddy, TL Lasho, CM Finke, RP Ketterling, ... American journal of hematology 94 (7), 767-779, 2019 | 69 | 2019 |
| Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association … P Li, S Jayarama, L Ganesh, D Mordi, R Carr, P Kanteti, N Hay, ... Journal of Biological Chemistry 285 (29), 22713-22722, 2010 | 52 | 2010 |
| Clinicopathologic characteristics, prognostication and treatment outcomes for myelodysplastic/myeloproliferative neoplasm, unclassifiable (MDS/MPN-U): Mayo Clinic-Moffitt … AA Mangaonkar, DM Swoboda, G Coltro, TL Lasho, PJ Novotny, ... Leukemia 34 (2), 656-661, 2020 | 47 | 2020 |
| LSD1, a double-edged sword, confers dynamic chromatin regulation but commonly promotes aberrant cell growth MM Kozub, RM Carr, GL Lomberk, ME Fernandez-Zapico F1000Research 6, 2016, 2017 | 44 | 2017 |
| Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers TL Hogenson, H Xie, WJ Phillips, MD Toruner, JJ Li, IP Horn, DJ Kennedy, ... JCI insight 7 (22), e158060, 2022 | 38 | 2022 |
| GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression EJ Tolosa, MG Fernandez-Barrena, E Iguchi, AL McCleary-Wheeler, ... Biochemical Journal 477 (17), 3131-3145, 2020 | 37 | 2020 |
| Prognostic impact and timing considerations for allogeneic hematopoietic stem cell transplantation in chronic myelomonocytic leukemia P Pophali, A Matin, AA Mangaonkar, R Carr, M Binder, A Al-Kali, ... Blood cancer journal 10 (11), 121, 2020 | 36 | 2020 |
| Spectrum of abnormalities and clonal transformation in germline RUNX1 familial platelet disorder and a genomic comparative analysis with somatic RUNX1 mutations in MDS/MPN … EC DiFilippo, G Coltro, RM Carr, AA Mangaonkar, M Binder, SP Khan, ... Leukemia 34 (9), 2519-2524, 2020 | 33 | 2020 |
| Targeting the metabolic pathway of human colon cancer overcomes resistance to TRAIL-induced apoptosis RM Carr, G Qiao, J Qin, S Jayaraman, BS Prabhakar, AV Maker Cell death discovery 2 (1), 1-13, 2016 | 32 | 2016 |
| Bone marrow dendritic cell aggregates associate with systemic immune dysregulation in chronic myelomonocytic leukemia AA Mangaonkar, KK Reichard, M Binder, G Coltro, TL Lasho, RM Carr, ... Blood Advances 4 (21), 5425-5430, 2020 | 28 | 2020 |
| IG20/MADD plays a critical role in glucose-induced insulin secretion L Li, Y Wang, R Carr, CS Haddad, Z Li, L Qian, J Oberholzer, AV Maker, ... Diabetes 63 (5), 1612-1623, 2014 | 27 | 2014 |
| SF3B1-mutant CMML defines a predominantly dysplastic CMML subtype with a superior acute leukemia–free survival K Wudhikarn, S Loghavi, AA Mangaonkar, A Al-Kali, M Binder, R Carr, ... Blood Advances 4 (22), 5716-5721, 2020 | 25 | 2020 |
| Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia M Binder, RM Carr, TL Lasho, CM Finke, AA Mangaonkar, CL Pin, ... Nature communications 13 (1), 1434, 2022 | 22 | 2022 |
| Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer AL McCleary-Wheeler, RM Carr, SR Palmer, TC Smyrk, JB Allred, ... Pancreatology 20 (1), 101-109, 2020 | 20 | 2020 |
| Epigenetics of cancer-associated muscle catabolism RM Carr, E Enriquez-Hesles, RLO Olson, A Jatoi, J Doles, ... Epigenomics 9 (10), 1259-1265, 2017 | 19 | 2017 |
| The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex RM Carr, PAR Duran, EJ Tolosa, C Ma, AM Oseini, CD Moser, BA Banini, ... Journal of Biological Chemistry 295 (9), 2698-2712, 2020 | 16 | 2020 |
Dr. Mrinal PatnaikAssociate Professor of Medicine, Mayo Clinic College of Medicine, Rochester, MinnesotaVerified email at mayo.edu