| Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells P Sacchetti, KM Sousa, AC Hall, I Liste, KR Steffensen, S Theofilopoulos, ... Cell stem cell 5 (4), 409-419, 2009 | 176 | 2009 |
| Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain? M Ogundare, S Theofilopoulos, A Lockhart, LJ Hall, E Arenas, J Sjövall, ... Journal of Biological Chemistry 285 (7), 4666-4679, 2010 | 143 | 2010 |
| Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis S Theofilopoulos, Y Wang, SS Kitambi, P Sacchetti, KM Sousa, K Bodin, ... Nature chemical biology 9 (2), 126-133, 2013 | 142 | 2013 |
| Cholestenoic acids regulate motor neuron survival via liver X receptors S Theofilopoulos, WJ Griffiths, PJ Crick, S Yang, A Meljon, M Ogundare, ... The Journal of clinical investigation 124 (11), 4829, 2014 | 107 | 2014 |
| The differentiation potential of human foetal neuronal progenitor cells in vitro SS Riaz, S Theofilopoulos, E Jauniaux, GM Stern, HF Bradford Developmental brain research 153 (1), 39-51, 2004 | 82 | 2004 |
| Analysis of bioactive oxysterols in newborn mouse brain by LC/MS A Meljon, S Theofilopoulos, CHL Shackleton, GL Watson, NB Javitt, ... Journal of Lipid Research 53 (11), 2469-2483, 2012 | 64 | 2012 |
| Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons. L Čajánek, RS Ganji, C Henriques-Oliveira, S Theofilopoulos, P Koník, ... Molecular and Cellular Biology, 2012 | 55 | 2012 |
| The neuronal survival effects of rasagiline and deprenyl on fetal human and rat ventral mesencephalic neurones in culture J Goggi, S Theofilopoulos, SS Riaz, E Jauniaux, GM Stern, HF Bradford Neuroreport 11 (18), 3937-3941, 2000 | 52 | 2000 |
| Targeted lipidomic analysis of oxysterols in the embryonic central nervous system Y Wang, KM Sousa, K Bodin, S Theofilopoulos, P Sacchetti, M Hornshaw, ... Molecular bioSystems 5 (5), 529-541, 2009 | 50 | 2009 |
| Parallel induction of the formation of dopamine and its metabolites with induction of tyrosine hydroxylase expression in foetal rat and human cerebral cortical cells by brain … S Theofilopoulos, J Goggi, SS Riaz, E Jauniaux, GM Stern, HF Bradford Developmental Brain Research 127 (2), 111-122, 2001 | 49 | 2001 |
| 24(S),25-Epoxycholesterol and cholesterol 24S-hydroxylase (CYP46A1) overexpression promote midbrain dopaminergic neurogenesis in vivo S Theofilopoulos, WAA de Oliveira, S Yang, E Yutuc, A Saeed, ... Journal of Biological Chemistry, jbc. RA118. 005639, 2019 | 45 | 2019 |
| Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma WJ Griffiths, PJ Crick, A Meljon, S Theofilopoulos, J Abdel-Khalik, E Yutuc, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 41 | 2019 |
| Dopamine receptor antagonists enhance proliferation and neurogenesis of midbrain Lmx1a-expressing progenitors E Hedlund, L Belnoue, S Theofilopoulos, C Salto, C Bye, C Parish, ... Scientific reports 6, 2016 | 41 | 2016 |
| The Matricellular Protein R-Spondin 2 Promotes Midbrain Dopaminergic Neurogenesis and Differentiation D Gyllborg, M Ahmed, EM Toledo, S Theofilopoulos, S Yang, ... Stem Cell Reports 11 (3), 651-664, 2018 | 31 | 2018 |
| Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis D Ribeiro, K Ellwanger, D Glagow, S Theofilopoulos, NS Corsini, ... PLoS One 6 (2), e15786, 2011 | 30 | 2011 |
| Liver X receptors and cholesterol metabolism: role in ventral midbrain development and neurodegeneration S Theofilopoulos, E Arenas F1000Prime Reports 7, 37, 2015 | 22 | 2015 |
| Mining for Oxysterols in Cyp7b1−/− Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5 A Meljon, PJ Crick, E Yutuc, J Yau L., JR Seckl, S Theofilopoulos, ... Biomolecules 9 (4), 149, 2019 | 17 | 2019 |
| The cerebrospinal fluid profile of cholesterol metabolites in Parkinson’s disease and their association with disease state and clinical features WJ Griffiths, J Abdel-Khalik, SF Moore, RS Wijeyekoon, PJ Crick, E Yutuc, ... Frontiers in Aging Neuroscience 13 (685594), 2021 | 15 | 2021 |
| 12-O-tetradecanoyl-phorbol-13-acetate-dependent up-regulation of dopaminergic gene expression requires Ras and neurofibromin in human IMR-32 neuroblastoma D Mangoura, S Theofilopoulos, S Karouzaki, E Tsirimonaki JOURNAL OF NEUROCHEMISTRY 97 (S1), 97-103, 2006 | 14 | 2006 |
| Novel function of the human presqualene diphosphate phosphatase as a type II phosphatidate phosphatase in phosphatidylcholine and triacylglyceride biosynthesis pathways S Theofilopoulos, A Lykidis, G Leondaritis, D Mangoura BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1781 (11 …, 2008 | 6 | 2008 |
William J GriffithsSwansea UniversityVerified email at swansea.ac.ukPaola SacchettiAssociate Professor, University of HartfordVerified email at hartford.edu
Kyle M. SousaProfessor, Pharmaceutical SciencesVerified email at llu.edu
Jan-Ake GustafssonRobert A. Welch Professor, Department of Biology and Biochemistry, University of HoustonVerified email at central.uh.edu
Eylan YutucSwansea UniversityVerified email at swansea.ac.uk
Eric JauniauxProfessor in Obstetrics and Fetal medicineVerified email at ucl.ac.uk
Clare ParishFlorey Institute of Neuroscience and Mental Health, The University of MelbourneVerified email at unimelb.edu.au
Toledo EMNovo Nordisk Research Centre OxfordVerified email at novonordisk.com
Norman B JavittResearh Professor of Medicine and Pediatrics New York University-Grossman School of MedicineVerified email at nyulangone.org
Lukas CajanekMasaryk University, Faculty of Medicine, BrnoVerified email at med.muni.cz
Martin HornshawThermo Fisher ScientificVerified email at thermofisher.com
Ahmed SaeedHuman Resource ManagerVerified email at imaegypt.com
Angel Cedazo-MinguezKarolinska Institutet (Sweden)Verified email at ki.se
