DNMT1-interacting RNAs block gene-specific DNA methylation A Di Ruscio, AK Ebralidze, T Benoukraf, G Amabile, LA Goff, J Terragni, ... Nature 503 (7476), 371-376, 2013 | 599 | 2013 |
H3K4 tri‐methylation provides an epigenetic signature of active enhancers A Pekowska, T Benoukraf, J Zacarias‐Cabeza, M Belhocine, F Koch, ... The EMBO journal 30 (20), 4198-4210, 2011 | 379 | 2011 |
Whole genome DNA methylation: beyond genes silencing R Tirado-Magallanes, K Rebbani, R Lim, S Pradhan, T Benoukraf Oncotarget 8 (3), 5629, 2016 | 157 | 2016 |
A unique H3K4me2 profile marks tissue-specific gene regulation A Pekowska, T Benoukraf, P Ferrier, S Spicuglia Genome research 20 (11), 1493-1502, 2010 | 156 | 2010 |
Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model EA Bard-Chapeau, AT Nguyen, AG Rust, A Sayadi, P Lee, BQ Chua, ... Nature genetics 46 (1), 24-32, 2014 | 129 | 2014 |
Hydrogel-based colorectal cancer organoid co-culture models X Luo, ELS Fong, C Zhu, QXX Lin, M Xiong, A Li, T Li, T Benoukraf, H Yu, ... Acta biomaterialia 132, 461-472, 2021 | 119 | 2021 |
Increased intron retention is a post‐transcriptional signature associated with progressive aging and Alzheimer’s disease S Adusumalli, ZK Ngian, WQ Lin, T Benoukraf, CT Ong Aging cell 18 (3), e12928, 2019 | 116 | 2019 |
NanoVar: accurate characterization of patients’ genomic structural variants using low-depth nanopore sequencing CY Tham, R Tirado-Magallanes, Y Goh, MJ Fullwood, BTH Koh, W Wang, ... Genome biology 21, 1-15, 2020 | 103 | 2020 |
Wanted DEAD/H or Alive: Helicases Winding Up in Cancers C Wanpei, C Zhi Xiong, R Grishma, S Shikha Satendra, C Zhang’e, ... J Natl Cancer Inst., 2017 | 103* | 2017 |
Methodological aspects of whole-genome bisulfite sequencing analysis S Adusumalli, MF Mohd Omar, R Soong, T Benoukraf Briefings in bioinformatics 16 (3), 369-379, 2015 | 102 | 2015 |
Generation of matched patient-derived xenograft in vitro-in vivo models using 3D macroporous hydrogels for the study of liver cancer ELS Fong, TB Toh, QXX Lin, Z Liu, L Hooi, MBMA Rashid, T Benoukraf, ... Biomaterials 159, 229-240, 2018 | 72 | 2018 |
MethMotif: an integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles QX Xuan Lin, S Sian, O An, D Thieffry, S Jha, T Benoukraf Nucleic acids research 47 (D1), D145-D154, 2019 | 70 | 2019 |
ZNF143 mediates CTCF-bound promoter–enhancer loops required for murine hematopoietic stem and progenitor cell function Q Zhou, M Yu, R Tirado-Magallanes, B Li, L Kong, M Guo, ZH Tan, S Lee, ... Nature communications 12 (1), 43, 2021 | 56 | 2021 |
Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies A Saei, M Palafox, T Benoukraf, N Kumari, PW Jaynes, PV Iyengar, ... Journal of Experimental Medicine 215 (7), 1913-1928, 2018 | 51 | 2018 |
NicE-seq: high resolution open chromatin profiling VKC Ponnaluri, G Zhang, PO Estève, G Spracklin, S Sian, S Xu, ... Genome biology 18, 1-15, 2017 | 51 | 2017 |
β-Catenin–TCF/LEF signaling promotes steady-state and emergency granulopoiesis via G-CSF receptor upregulation P Danek, M Kardosova, L Janeckova, E Karkoulia, K Vanickova, ... Blood, The Journal of the American Society of Hematology 136 (22), 2574-2587, 2020 | 50 | 2020 |
Disruption of the C/EBPα—miR-182 balance impairs granulocytic differentiation AA Wurm, P Zjablovskaja, M Kardosova, D Gerloff, D Bräuer-Hartmann, ... Nature communications 8 (1), 46, 2017 | 49 | 2017 |
CoCAS: a ChIP-on-chip analysis suite T Benoukraf, P Cauchy, R Fenouil, A Jeanniard, F Koch, S Jaeger, ... Bioinformatics 25 (7), 954-955, 2009 | 49 | 2009 |
Hepatocellular carcinoma organoid co-cultures mimic angiocrine crosstalk to generate inflammatory tumor microenvironment JTC Lim, LG Kwang, NCW Ho, CCM Toh, NSH Too, L Hooi, T Benoukraf, ... Biomaterials 284, 121527, 2022 | 48 | 2022 |
Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance A Numata, HS Kwok, QL Zhou, J Li, R Tirado-Magallanes, VE Angarica, ... Blood, The Journal of the American Society of Hematology 136 (15), 1735-1747, 2020 | 43 | 2020 |