| Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 310 | 2016 |
| Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors RS Ferreira, A Simeonov, A Jadhav, O Eidam, BT Mott, MJ Keiser, ... Journal of medicinal chemistry 53 (13), 4891-4905, 2010 | 276 | 2010 |
| Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease A Jadhav, RS Ferreira, C Klumpp, BT Mott, CP Austin, J Inglese, ... Journal of medicinal chemistry 53 (1), 37-51, 2010 | 269 | 2010 |
| Docking and chemoinformatic screens for new ligands and targets P Kolb, RS Ferreira, JJ Irwin, BK Shoichet Current opinion in biotechnology 20 (4), 429-436, 2009 | 237 | 2009 |
| Two approaches to discovering and developing new drugs for Chagas disease JH McKerrow, PS Doyle, JC Engel, LM Podust, SA Robertson, R Ferreira, ... Memórias do Instituto Oswaldo Cruz 104, 263-269, 2009 | 225 | 2009 |
| Integrating molecular docking and molecular dynamics simulations LHS Santos, RS Ferreira, ER Caffarena Docking screens for drug discovery, 13-34, 2019 | 192 | 2019 |
| Identification and optimization of inhibitors of trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB BT Mott, RS Ferreira, A Simeonov, A Jadhav, KKH Ang, W Leister, M Shen, ... Journal of medicinal chemistry 53 (1), 52-60, 2010 | 169 | 2010 |
| Docking for fragment inhibitors of AmpC β-lactamase DG Teotico, K Babaoglu, GJ Rocklin, RS Ferreira, AM Giannetti, ... Proceedings of the National Academy of Sciences 106 (18), 7455-7460, 2009 | 136 | 2009 |
| 2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation MV de Oliveira Cardoso, LRP de Siqueira, EB da Silva, LB Costa, ... European Journal of Medicinal Chemistry 86, 48-59, 2014 | 121 | 2014 |
| Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases C Bryant, ID Kerr, M Debnath, KKH Ang, J Ratnam, RS Ferreira, ... Bioorganic & medicinal chemistry letters 19 (21), 6218-6221, 2009 | 103 | 2009 |
| Synthesis, Biological Evaluation, and Structure–Activity Relationships of Potent Noncovalent and Nonpeptidic Cruzain Inhibitors as Anti-Trypanosoma cruzi Agents RS Ferreira, MA Dessoy, I Pauli, ML Souza, R Krogh, AIL Sales, G Oliva, ... Journal of medicinal chemistry 57 (6), 2380-2392, 2014 | 101 | 2014 |
| Divergent modes of enzyme inhibition in a homologous structure− activity series RS Ferreira, C Bryant, KKH Ang, JH McKerrow, BK Shoichet, AR Renslo Journal of Medicinal Chemistry 52 (16), 5005-5008, 2009 | 93 | 2009 |
| Antidepressant-like effect of terpineol in an inflammatory model of depression: involvement of the cannabinoid system and D2 dopamine receptor G Vieira, J Cavalli, ECD Gonçalves, SFP Braga, RS Ferreira, ARS Santos, ... Biomolecules 10 (5), 792, 2020 | 80 | 2020 |
| Synthesis and leishmanicidal activity of eugenol derivatives bearing 1, 2, 3-triazole functionalities RR Teixeira, PAR Gazolla, AM da Silva, MPG Borsodi, BR Bergmann, ... European Journal of Medicinal Chemistry 146, 274-286, 2018 | 77 | 2018 |
| Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni … NC Fonseca, LF da Cruz, F da Silva Villela, GA do Nascimento Pereira, ... Antimicrobial Agents and Chemotherapy 59 (5), 2666-2677, 2015 | 76 | 2015 |
| Structural Investigation of Anti-Trypanosoma cruzi 2-Iminothiazolidin-4-ones Allows the Identification of Agents with Efficacy in Infected Mice DRM Moreira, SPM Costa, MZ Hernandes, MM Rabello, ... Journal of Medicinal Chemistry 55 (24), 10918-10936, 2012 | 76 | 2012 |
| Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death DRM Moreira, ADT de Oliveira, PAT de Moraes Gomes, CA de Simone, ... European journal of medicinal chemistry 75, 467-478, 2014 | 70 | 2014 |
| Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents MZ Hernandes, MM Rabello, ACL Leite, MVO Cardoso, DRM Moreira, ... Bioorganic & Medicinal Chemistry 18 (22), 7826-7835, 2010 | 68 | 2010 |
| Synthesis and structure–activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma Cruzi Cruzain JWP Espíndola, MV de Oliveira Cardoso, GB de Oliveira Filho, ... European Journal of Medicinal Chemistry 101, 818-835, 2015 | 67 | 2015 |
| Schistosoma mansoni SmKI-1 serine protease inhibitor binds to elastase and impairs neutrophil function and inflammation SB Morais, BC Figueiredo, NRG Assis, DM Alvarenga, ... PLoS pathogens 14 (2), e1006870, 2018 | 65 | 2018 |
Diogo Rodrigo Magalhaes MoreiraCentro de Pesquisas Gonçalo MonizVerified email at bahia.fiocruz.br
