| Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling EW Weber, KR Parker, E Sotillo, RC Lynn, H Anbunathan, J Lattin, ... Science 372 (6537), eaba1786, 2021 | 454* | 2021 |
| Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2 SCA Nielsen, F Yang, KJL Jackson, RA Hoh, K Röltgen, GH Jean, ... Cell host & microbe 28 (4), 516-525. e5, 2020 | 247 | 2020 |
| The transcription factor STAT6 mediates direct repression of inflammatory enhancers and limits activation of alternatively polarized macrophages Z Czimmerer, B Daniel, A Horvath, D Rückerl, G Nagy, M Kiss, M Peloquin, ... Immunity 48 (1), 75-90. e6, 2018 | 230 | 2018 |
| Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA T Sallam, M Jones, BJ Thomas, X Wu, T Gilliland, K Qian, A Eskin, ... Nature medicine 24 (3), 304-312, 2018 | 209 | 2018 |
| Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence JA Belk, W Yao, N Ly, KA Freitas, YT Chen, Q Shi, AM Valencia, E Shifrut, ... Cancer cell 40 (7), 768-786. e7, 2022 | 189 | 2022 |
| Macrophage PPARγ, a lipid activated transcription factor controls the growth factor GDF3 and skeletal muscle regeneration T Varga, R Mounier, A Patsalos, P Gogolák, M Peloquin, A Horvath, A Pap, ... Immunity 45 (5), 1038-1051, 2016 | 170 | 2016 |
| The nuclear receptor PPARγ controls progressive macrophage polarization as a ligand-insensitive epigenomic ratchet of transcriptional memory B Daniel, G Nagy, Z Czimmerer, A Horvath, DW Hammers, ... Immunity 49 (4), 615-626. e6, 2018 | 154 | 2018 |
| Epigenetic regulation of T cell exhaustion JA Belk, B Daniel, AT Satpathy Nature immunology 23 (6), 848-860, 2022 | 143 | 2022 |
| Hepatocyte-macrophage acetoacetate shuttle protects against tissue fibrosis P Puchalska, SE Martin, X Huang, JE Lengfeld, B Daniel, MJ Graham, ... Cell metabolism 29 (2), 383-398. e7, 2019 | 113 | 2019 |
| RASA2 ablation in T cells boosts antigen sensitivity and long-term function J Carnevale, E Shifrut, N Kale, WA Nyberg, F Blaeschke, YY Chen, Z Li, ... Nature 609 (7925), 174-182, 2022 | 108 | 2022 |
| The active enhancer network operated by liganded RXR supports angiogenic activity in macrophages B Daniel, G Nagy, N Hah, A Horvath, Z Czimmerer, S Poliska, T Gyuris, ... Genes & development 28 (14), 1562-1577, 2014 | 102 | 2014 |
| Divergent clonal differentiation trajectories of T cell exhaustion B Daniel, KE Yost, S Hsiung, K Sandor, Y Xia, Y Qi, KJ Hiam-Galvez, ... Nature immunology 23 (11), 1614-1627, 2022 | 101 | 2022 |
| Enhanced T cell effector activity by targeting the Mediator kinase module KA Freitas, JA Belk, E Sotillo, PJ Quinn, MC Ramello, M Malipatlolla, ... Science 378 (6620), eabn5647, 2022 | 67 | 2022 |
| The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages B Daniel, G Nagy, A Horvath, Z Czimmerer, I Cuaranta-Monroy, S Poliska, ... Nucleic acids research 46 (9), 4425-4439, 2018 | 61 | 2018 |
| SETDB2 links glucocorticoid to lipid metabolism through Insig2a regulation M Roqueta-Rivera, RM Esquejo, PE Phelan, K Sandor, B Daniel, ... Cell metabolism 24 (3), 474-484, 2016 | 61 | 2016 |
| Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis JS Weinstock, J Gopakumar, BB Burugula, MM Uddin, N Jahn, JA Belk, ... Nature 616 (7958), 755-763, 2023 | 58* | 2023 |
| A growth factor–expressing macrophage subpopulation orchestrates regenerative inflammation via GDF-15 A Patsalos, L Halasz, MA Medina-Serpas, WK Berger, B Daniel, ... Journal of Experimental Medicine 219 (1), e20210420, 2021 | 51 | 2021 |
| TCR-BERT: learning the grammar of T-cell receptors for flexible antigen-binding analyses KE Wu, K Yost, B Daniel, J Belk, Y Xia, T Egawa, A Satpathy, H Chang, ... Machine Learning in Computational Biology, 194-229, 2024 | 50 | 2024 |
| BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen Y Xia, K Sandor, JA Pai, B Daniel, S Raju, R Wu, S Hsiung, Y Qi, ... Immunity 55 (7), 1200-1215. e6, 2022 | 48 | 2022 |
| The IL-4/STAT6 signaling axis establishes a conserved microRNA signature in human and mouse macrophages regulating cell survival via miR-342-3p Z Czimmerer, T Varga, M Kiss, CO Vázquez, QM Doan-Xuan, D Rückerl, ... Genome medicine 8, 1-22, 2016 | 47 | 2016 |
Laszlo NagyProfessor and Co-Director, Johns Hopkins University School of Medicine and University of DebrecenVerified email at jhmi.edu