| Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing Q Cheng, T Wei, L Farbiak, LT Johnson, SA Dilliard, DJ Siegwart Nature nanotechnology 15 (4), 313-320, 2020 | 1377 | 2020 |
| Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR–Cas gene editing S Liu, Q Cheng, T Wei, X Yu, LT Johnson, L Farbiak, DJ Siegwart Nature materials 20 (5), 701-710, 2021 | 399 | 2021 |
| Stimulus-specific combinatorial functionality of neuronal c-fos enhancers JY Joo, K Schaukowitch, L Farbiak, G Kilaru, TK Kim Nature neuroscience 19 (1), 75-83, 2016 | 256 | 2016 |
| Dendrimer‐based lipid nanoparticles deliver therapeutic FAH mRNA to normalize liver function and extend survival in a mouse model of hepatorenal tyrosinemia type I Q Cheng, T Wei, Y Jia, L Farbiak, K Zhou, S Zhang, Y Wei, H Zhu, ... Advanced materials 30 (52), 1805308, 2018 | 195 | 2018 |
| Enhancing CRISPR/Cas gene editing through modulating cellular mechanical properties for cancer therapy D Zhang, G Wang, X Yu, T Wei, L Farbiak, LT Johnson, AM Taylor, J Xu, ... Nature nanotechnology 17 (7), 777-787, 2022 | 139 | 2022 |
| Optimization of phospholipid chemistry for improved lipid nanoparticle (LNP) delivery of messenger RNA (mRNA) E Álvarez-Benedicto, L Farbiak, MM Ramírez, X Wang, LT Johnson, ... Biomaterials science 10 (2), 549-559, 2022 | 106 | 2022 |
| Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing T Wei, Q Cheng, L Farbiak, DG Anderson, R Langer, DJ Siegwart ACS nano 14 (8), 9243-9262, 2020 | 102 | 2020 |
| All‐in‐one dendrimer‐based lipid nanoparticles enable precise HDR‐mediated gene editing in vivo L Farbiak, Q Cheng, T Wei, E Álvarez‐Benedicto, LT Johnson, S Lee, ... Advanced Materials 33 (30), 2006619, 2021 | 80 | 2021 |
| Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery JR Melamed, KA Hajj, N Chaudhary, D Strelkova, ML Arral, N Pardi, ... Journal of Controlled Release 341, 206-214, 2022 | 59 | 2022 |
| The interplay of quaternary ammonium lipid structure and protein corona on lung-specific mRNA delivery by selective organ targeting (SORT) nanoparticles SA Dilliard, Y Sun, MO Brown, YC Sung, S Chatterjee, L Farbiak, ... Journal of Controlled Release 361, 361-372, 2023 | 41 | 2023 |
| Lipid Nanoparticle (LNP) Chemistry Can Endow Unique In Vivo RNA Delivery Fates within the Liver That Alter Therapeutic Outcomes in a Cancer Model LT Johnson, D Zhang, K Zhou, SM Lee, S Liu, SA Dilliard, L Farbiak, ... Molecular pharmaceutics 19 (11), 3973-3986, 2022 | 34 | 2022 |
| Hydrophobic optimization of functional poly (TPAE-co-suberoyl chloride) for extrahepatic mRNA delivery following Intravenous Administration X Yu, S Liu, Q Cheng, SM Lee, T Wei, D Zhang, L Farbiak, LT Johnson, ... Pharmaceutics 13 (11), 1914, 2021 | 8 | 2021 |
| Effects of lower-and higher-volume resistance exercise on serum total and free testosterone, skeletal muscle testosterone and dihydrotestosterone content, and skeletal muscle … L Farbiak | 7 | 2013 |
| Expanding RNAi to kidneys, lungs, and spleen via selective ORgan targeting (SORT) siRNA lipid nanoparticles A Vaidya, S Moore, S Chatterjee, E Guerrero, M Kim, L Farbiak, ... Advanced Materials 36 (35), 2313791, 2024 | 2 | 2024 |
| In situ production and secretion of proteins endow therapeutic benefit against psoriasiform dermatitis and melanoma Q Cheng, L Farbiak, A Vaidya, E Guerrero, EE Lee, EK Rose, X Wang, ... Proceedings of the National Academy of Sciences 120 (52), e2313009120, 2023 | 1 | 2023 |
| Suggested searches IR Simpson, KA McKinnon, D Kennedy, DM Lawrence, R Seager, ... Perspective, 2024 | | 2024 |
| All-in-one dendrimer-based lipid nanoparticles enable precise hdr-mediated gene editing in vivo DJ Siegwart, L Farbiak US Patent App. 18/556,614, 2024 | | 2024 |
| Re-engineering of Dendrimer-Based Lipid Nanoparticles for Efficient and Precise HDR-Mediated Gene Editing LJ Farbiak | | 2021 |
| LIPID NANOPARTICLE DELIVERY OF MRNA TO FULLY DIFFERENTIATED, PATIENT-DERIVED BRONCHIAL EPITHELIAL CELLS ML Coquelin, R Devulapally, L Farbiak, L Johnson, RJ Bridges, ... PEDIATRIC PULMONOLOGY 54, S217-S217, 2019 | | 2019 |
Daniel SiegwartProfessor, University of Texas Southwestern Medical CenterVerified email at utsouthwestern.edu
