Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations DM Rissin, CW Kan, TG Campbell, SC Howes, DR Fournier, L Song, ... Nature biotechnology 28 (6), 595-599, 2010 | 2196 | 2010 |
The Simoa HD-1 analyzer: a novel fully automated digital immunoassay analyzer with single-molecule sensitivity and multiplexing DH Wilson, DM Rissin, CW Kan, DR Fournier, T Piech, TG Campbell, ... Journal of laboratory automation 21 (4), 533-547, 2016 | 459 | 2016 |
Simultaneous detection of single molecules and singulated ensembles of molecules enables immunoassays with broad dynamic range DM Rissin, DR Fournier, T Piech, CW Kan, TG Campbell, L Song, ... Analytical chemistry 83 (6), 2279-2285, 2011 | 267 | 2011 |
Digital concentration readout of single enzyme molecules using femtoliter arrays and Poisson statistics DM Rissin, DR Walt Nano letters 6 (3), 520-523, 2006 | 235 | 2006 |
Single molecule enzyme-linked immunosorbent assays: theoretical considerations L Chang, DM Rissin, DR Fournier, T Piech, PP Patel, DH Wilson, ... Journal of immunological methods 378 (1-2), 102-115, 2012 | 208 | 2012 |
Hypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid β levels in humans H Zetterberg, E Mörtberg, L Song, L Chang, GK Provuncher, PP Patel, ... PloS one 6 (12), e28263, 2011 | 198 | 2011 |
Multiplexed single molecule immunoassays DM Rissin, CW Kan, L Song, AJ Rivnak, MW Fishburn, Q Shao, T Piech, ... Lab on a Chip 13 (15), 2902-2911, 2013 | 175 | 2013 |
Optical imaging fiber-based live bacterial cell array biosensor I Biran, DM Rissin, EZ Ron, DR Walt Analytical Biochemistry 315 (1), 106-113, 2003 | 157 | 2003 |
Distinct and long-lived activity states of single enzyme molecules DM Rissin, HH Gorris, DR Walt Journal of the American Chemical Society 130 (15), 5349-5353, 2008 | 148 | 2008 |
Stochastic inhibitor release and binding from single-enzyme molecules HH Gorris, DM Rissin, DR Walt Proceedings of the National Academy of Sciences 104 (45), 17680-17685, 2007 | 146 | 2007 |
Isolation and detection of single molecules on paramagnetic beads using sequential fluid flows in microfabricated polymer array assemblies CW Kan, AJ Rivnak, TG Campbell, T Piech, DM Rissin, M Mösl, A Peterça, ... Lab on a Chip 12 (5), 977-985, 2012 | 137 | 2012 |
Digital readout of target binding with attomole detection limits via enzyme amplification in femtoliter arrays DM Rissin, DR Walt Journal of the American Chemical Society 128 (19), 6286-6287, 2006 | 118 | 2006 |
Use of colorimetric test strips for monitoring the effect of hemodialysis on salivary nitrite and uric acid in patients with end-stage renal disease: a proof of principle TM Blicharz, DM Rissin, M Bowden, RB Hayman, C DiCesare, JS Bhatia, ... Clinical chemistry 54 (9), 1473-1480, 2008 | 112 | 2008 |
A fully-automated, six-plex single molecule immunoassay for measuring cytokines in blood AJ Rivnak, DM Rissin, CW Kan, L Song, MW Fishburn, T Piech, ... Journal of immunological methods 424, 20-27, 2015 | 102 | 2015 |
Ultra-sensitive detection of molecules on single molecule arrays DC Duffy, E Ferrell, JD Randall, DM Rissin, DR Walt US Patent 8,222,047, 2012 | 87 | 2012 |
Ultra-sensitive detection of molecules or particles using beads or other capture objects DC Duffy, DM Rissin, DR Walt, D Fournier, C Kan US Patent 8,236,574, 2012 | 85 | 2012 |
Microsensor arrays for saliva diagnostics DR Walt, TM Blicharz, RB Hayman, DM Rissin, M Bowden, WL Siqueira, ... Annals of the New York Academy of Sciences 1098 (1), 389-400, 2007 | 75 | 2007 |
Ultra-sensitive detection of molecules or particles using beads or other capture objects DC Duffy, DM Rissin, DR Walt, D Fournier, C Kan US Patent 9,482,662, 2016 | 74 | 2016 |
Digital enzyme-linked immunosorbent assays with sub-attomolar detection limits based on low numbers of capture beads combined with high efficiency bead analysis CW Kan, CI Tobos, DM Rissin, AD Wiener, RE Meyer, DM Svancara, ... Lab on a Chip 20 (12), 2122-2135, 2020 | 72 | 2020 |
Methods and arrays for detecting cells and cellular components in small defined volumes DR Walt, DM Rissin US Patent 8,460,878, 2013 | 66 | 2013 |