| Metamorphic enzyme assembly in polyketide diversification L Gu, B Wang, A Kulkarni, TW Geders, RV Grindberg, L Gerwick, ... Nature 459 (7247), 731-735, 2009 | 198 | 2009 |
| New tricks from ancient algae: natural products biosynthesis in marine cyanobacteria AC Jones, L Gu, CM Sorrels, DH Sherman, WH Gerwick Current opinion in chemical biology 13 (2), 216-223, 2009 | 137 | 2009 |
| GNAT-like strategy for polyketide chain initiation L Gu, TW Geders, B Wang, WH Gerwick, K Håkansson, JL Smith, ... Science 318 (5852), 970-974, 2007 | 135 | 2007 |
| Monodisperse Hsp16. 3 nonamer exhibits dynamic dissociation and reassociation, with the nonamer dissociation prerequisite for chaperone-like activity L Gu, A Abulimiti, W Li, Z Chang Journal of molecular biology 319 (2), 517-526, 2002 | 129 | 2002 |
| Improved cell-free RNA and protein synthesis system J Li, L Gu, J Aach, GM Church PLoS one 9 (9), e106232, 2014 | 120 | 2014 |
| Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair L Gu, J Jia, H Liu, K Håkansson, WH Gerwick, DH Sherman Journal of the American Chemical Society 128 (28), 9014-9015, 2006 | 113 | 2006 |
| Polyketide Decarboxylative Chain Termination Preceded by O-Sulfonation in Curacin A Biosynthesis L Gu, B Wang, A Kulkarni, JJ Gehret, KR Lloyd, L Gerwick, WH Gerwick, ... Journal of the American Chemical Society 131 (44), 16033-16035, 2009 | 109 | 2009 |
| Conformational switch triggered by α-ketoglutarate in a halogenase of curacin A biosynthesis D Khare, B Wang, L Gu, J Razelun, DH Sherman, WH Gerwick, ... Proceedings of the National Academy of Sciences 107 (32), 14099-14104, 2010 | 108 | 2010 |
| Multiplex single-molecule interaction profiling of DNA-barcoded proteins L Gu, C Li, J Aach, DE Hill, M Vidal, GM Church Nature 515 (7528), 554-557, 2014 | 90 | 2014 |
| Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase JJ Gehret, L Gu, WH Gerwick, P Wipf, DH Sherman, JL Smith Journal of Biological Chemistry 286 (16), 14445-14454, 2011 | 87 | 2011 |
| Polony gels enable amplifiable DNA stamping and spatial transcriptomics of chronic pain X Fu, L Sun, R Dong, JY Chen, R Silakit, LF Condon, Y Lin, S Lin, ... Cell 185 (24), 4621-4633. e17, 2022 | 86 | 2022 |
| Defining molecular glues with a dual-nanobody cannabidiol sensor S Cao, S Kang, H Mao, J Yao, L Gu, N Zheng Nature communications 13 (1), 815, 2022 | 71 | 2022 |
| Barcoded protein array for multiplex single-molecule interaction profiling GM Church, L Gu US Patent 10,858,698, 2020 | 71 | 2020 |
| Phylogenetic and Chemical Diversity of Three Chemotypes of Bloom-Forming Lyngbya Species (Cyanobacteria: Oscillatoriales) from Reefs of Southeastern Florida K Sharp, KE Arthur, L Gu, C Ross, G Harrison, SP Gunasekera, T Meickle, ... Applied and Environmental Microbiology 75 (9), 2879-2888, 2009 | 66 | 2009 |
| Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula: Insights into a decarboxylase involved in polyketide chain β-branching TW Geders, L Gu, JC Mowers, H Liu, WH Gerwick, K Hakansson, ... Journal of Biological Chemistry 282 (49), 35954-35963, 2007 | 64 | 2007 |
| Small heat shock protein Hsp16. 3 modulates its chaperone activity by adjusting the rate of oligomeric dissociation X Fu, C Liu, Y Liu, X Feng, L Gu, X Chen, Z Chang Biochemical and biophysical research communications 310 (2), 412-420, 2003 | 58 | 2003 |
| Structure and activity of DmmA, a marine haloalkane dehalogenase JJ Gehret, L Gu, TW Geders, WC Brown, L Gerwick, WH Gerwick, ... Protein Science 21 (2), 239-248, 2012 | 56 | 2012 |
| Continuous polony gels for tissue mapping with high resolution and RNA capture efficiency X Fu, L Sun, JY Chen, R Dong, Y Lin, RD Palmiter, S Lin, L Gu BioRxiv, 2021.03. 17.435795, 2021 | 55 | 2021 |
| Tandem acyl carrier proteins in the curacin biosynthetic pathway promote consecutive multienzyme reactions with a synergistic effect L Gu, EB Eisman, S Dutta, TM Franzmann, S Walter, WH Gerwick, ... Angewandte Chemie (International ed. in English) 50 (12), 2795, 2011 | 54 | 2011 |
| Characterization of molecular interactions between ACP and halogenase domains in the Curacin A polyketide synthase A Busche, D Gottstein, C Hein, N Ripin, I Pader, P Tufar, EB Eisman, L Gu, ... ACS chemical biology 7 (2), 378-386, 2012 | 50 | 2012 |
David H. ShermanUniversity of MichiganVerified email at umich.edu
