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James M. Downey
James M. Downey
Professor of Physiology, University of South Alabama
Verified email at southalabama.edu - Homepage
Title
Cited by
Cited by
Year
Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart.
GS Liu, J Thornton, DM Van Winkle, AW Stanley, RA Olsson, JM Downey
Circulation 84 (1), 350-356, 1991
18141991
Preconditioning the myocardium: from cellular physiology to clinical cardiology
DM Yellon, JM Downey
Physiological reviews 83 (4), 1113-1151, 2003
15092003
Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways
XM Yang, JB Proctor, L Cui, T Krieg, JM Downey, MV Cohen
Journal of the American College of Cardiology 44 (5), 1103-1110, 2004
9452004
Opening of Mitochondrial KATP Channels Triggers the Preconditioned State by Generating Free Radicals
T Pain, XM Yang, SD Critz, Y Yue, A Nakano, GS Liu, G Heusch, ...
Circulation research 87 (6), 460-466, 2000
9322000
Xanthine oxidase as a source of free radical damage in myocardial ischemia
DE Chambers, DA Parks, G Patterson, R Roy, JM McCord, S Yoshida, ...
Journal of molecular and cellular cardiology 17 (2), 145-152, 1985
9231985
Preconditioning protects ischemic rabbit heart by protein kinase C activation
K Ytrehus, Y Liu, JM Downey
American Journal of Physiology-Heart and Circulatory Physiology 266 (3 …, 1994
8911994
Ischemic Preconditioning: From Adenosine Receptor to KATP Channel
MV Cohen, CP Baines, JM Downey
Annual review of physiology 62 (1), 79-109, 2000
7042000
Role of bradykinin in protection of ischemic preconditioning in rabbit hearts
M Goto, Y Liu, XM Yang, JL Ardell, MV Cohen, JM Downey
Circulation research 77 (3), 611-621, 1995
7031995
Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardium
CP Baines, M Goto, JM Downey
Journal of molecular and cellular cardiology 29 (1), 207-216, 1997
6471997
Intravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction.
JD Thornton, GS Liu, RA Olsson, JM Downey
Circulation 85 (2), 659-665, 1992
6131992
The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis
MV Cohen, XM Yang, JM Downey
Circulation 115 (14), 1895-1903, 2007
555*2007
Ischemic preconditioning protects against infarction in rat heart
Y Liu, JM Downey
American Journal of Physiology-Heart and Circulatory Physiology 263 (4 …, 1992
5441992
Signaling pathways in ischemic preconditioning
JM Downey, AM Davis, MV Cohen
Heart failure reviews 12, 181-188, 2007
4902007
Preconditioning: state of the art myocardial protection
CS Lawson, JM Downey
Cardiovascular research 27 (4), 542-550, 1993
4831993
Volatile anesthetics protect the ischemic rabbit myocardium from infarction
DK Cope, KW Impastato, MV Cohen, JM Downey
The Journal of the American Society of Anesthesiologists 86 (3), 699-709, 1997
4701997
Inhibition of coronary blood flow by a vascular waterfall mechanism.
JM Downey, ES Kirk
Circulation research 36 (6), 753-760, 1975
4671975
Preconditioning causes improved wall motion as well as smaller infarcts after transient coronary occlusion in rabbits.
MV Cohen, GS Liu, JM Downey
Circulation 84 (1), 341-349, 1991
4541991
Signal transduction of ischemic preconditioning
R Schulz, MV Cohen, M Behrends, JM Downey, G Heusch
Cardiovascular research 52 (2), 181-198, 2001
4242001
Postconditioning’s protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3–kinase and guanylyl cyclase activation
XM Yang, S Philipp, JM Downey, MV Cohen
Basic research in cardiology 100, 57-63, 2005
4222005
Acetylcholine, bradykinin, opioids, and phenylephrine, but not adenosine, trigger preconditioning by generating free radicals and opening mitochondrial KATP channels
MV Cohen, XM Yang, GS Liu, G Heusch, JM Downey
Circulation research 89 (3), 273-278, 2001
4182001
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