SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract YJ Hou, K Okuda, CE Edwards, DR Martinez, T Asakura, KH Dinnon, ... Cell 182 (2), 429-446. e14, 2020 | 1577 | 2020 |
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice M Mall, BR Grubb, JR Harkema, WK O'Neal, RC Boucher Nature medicine 10 (5), 487-493, 2004 | 1112 | 2004 |
Muc5b is required for airway defence MG Roy, A Livraghi-Butrico, AA Fletcher, MM McElwee, SE Evans, ... Nature 505 (7483), 412-416, 2014 | 795 | 2014 |
Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons N Morral, W O’Neal, K Rice, M Leland, J Kaplan, PA Piedra, H Zhou, ... Proceedings of the National Academy of Sciences 96 (22), 12816-12821, 1999 | 494 | 1999 |
Defects in Yolk Sac Vasculogenesis, Chorioallantoic Fusion, and Embryonic Axis Elongation in Mice with Targeted Disruption of Yap65 EM Morin-Kensicki, BN Boone, M Howell, JR Stonebraker, J Teed, JG Alb, ... Molecular and cellular biology 26 (1), 77-87, 2006 | 492 | 2006 |
Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense M Kesimer, M Scull, B Brighton, G DeMaria, K Burns, W O'Neal, ... The FASEB Journal 23 (6), 1858, 2009 | 413 | 2009 |
Abnormal surface liquid pH regulation by cultured cystic fibrosis bronchial epithelium RD Coakley, BR Grubb, AM Paradiso, JT Gatzy, LG Johnson, SM Kreda, ... Proceedings of the National Academy of Sciences 100 (26), 16083-16088, 2003 | 367 | 2003 |
Airway mucin concentration as a marker of chronic bronchitis M Kesimer, AA Ford, A Ceppe, G Radicioni, R Cao, CW Davis, ... New England Journal of Medicine 377 (10), 911-922, 2017 | 365 | 2017 |
Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis H Corvol, SM Blackman, PY Boëlle, PJ Gallins, RG Pace, JR Stonebraker, ... Nature communications 6 (1), 8382, 2015 | 310 | 2015 |
Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl–secretory channel in mouse airways JR Rock, WK O'Neal, SE Gabriel, SH Randell, BD Harfe, RC Boucher, ... Journal of Biological Chemistry 284 (22), 14875-14880, 2009 | 306 | 2009 |
Frequency of exacerbations in patients with chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort MLK Han, PM Quibrera, EE Carretta, RG Barr, ER Bleecker, RP Bowler, ... The Lancet Respiratory Medicine 5 (8), 619-626, 2017 | 299 | 2017 |
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13. 2 FA Wright, LJ Strug, VK Doshi, CW Commander, SM Blackman, L Sun, ... Nature genetics 43 (6), 539-546, 2011 | 290 | 2011 |
Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort AT Hastie, FJ Martinez, JL Curtis, CM Doerschuk, NN Hansel, ... The Lancet Respiratory Medicine 5 (12), 956-967, 2017 | 281 | 2017 |
NSP4 elicits age-dependent diarrhea and Ca2+mediated I− influx into intestinal crypts of CF mice AP Morris, JK Scott, JM Ball, CQY Zeng, WK O’Neal, MK Estes American Journal of Physiology-Gastrointestinal and Liver Physiology 277 (2 …, 1999 | 262 | 1999 |
Localization of secretory mucins MUC5AC and MUC5B in normal/healthy human airways K Okuda, G Chen, DB Subramani, M Wolf, RC Gilmore, T Kato, ... American journal of respiratory and critical care medicine 199 (6), 715-727, 2019 | 261 | 2019 |
Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis L Sun, JM Rommens, H Corvol, W Li, X Li, TA Chiang, F Lin, R Dorfman, ... Nature genetics 44 (5), 562-569, 2012 | 247 | 2012 |
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol LA Lange, Y Hu, H Zhang, C Xue, EM Schmidt, ZZ Tang, C Bizon, ... The American Journal of Human Genetics 94 (2), 233-245, 2014 | 245 | 2014 |
Rho signaling regulates pannexin 1-mediated ATP release from airway epithelia L Seminario-Vidal, SF Okada, JI Sesma, SM Kreda, CA Van Heusden, ... Journal of Biological Chemistry 286 (30), 26277-26286, 2011 | 245 | 2011 |
Development of Chronic Bronchitis and Emphysema in β-Epithelial Na+ Channel–Overexpressing Mice MA Mall, JR Harkema, JB Trojanek, D Treis, A Livraghi, S Schubert, ... American journal of respiratory and critical care medicine 177 (7), 730-742, 2008 | 219 | 2008 |
Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs C Ehre, EN Worthington, RM Liesman, BR Grubb, D Barbier, WK O’Neal, ... Proceedings of the National Academy of Sciences 109 (41), 16528-16533, 2012 | 213 | 2012 |