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Tim Dierckx
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Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes
JE Neggers, B Kwanten, T Dierckx, H Noguchi, A Voet, L Bral, K Minner, ...
Nature Communications 9 (1), 502, 2018
1182018
Inflammatory gene expression profile and defective interferon‐γ and granzyme K in natural killer cells from systemic juvenile idiopathic arthritis patients
K Put, J Vandenhaute, A Avau, A Van Nieuwenhuijze, E Brisse, T Dierckx, ...
Arthritis & Rheumatology 69 (1), 213-224, 2017
932017
Low eukaryotic viral richness is associated with faecal microbiota transplantation success in patients with UC
N Conceição-Neto, W Deboutte, T Dierckx, K Machiels, J Wang, KC Yinda, ...
Gut 67 (8), 1558-1559, 2018
702018
An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans
M Delgobo, DAGB Mendes, E Kozlova, EL Rocha, GF Rodrigues-Luiz, ...
elife 8, e47013, 2019
462019
Systems approach reveals nuclear factor erythroid 2-related factor 2/protein kinase R crosstalk in human cutaneous leishmaniasis
ÁC Vivarini, TC Calegari-Silva, AM Saliba, VS Boaventura, ...
Frontiers in immunology 8, 1127, 2017
462017
ISG15-induced IL-10 is a novel anti-inflammatory myeloid axis disrupted during active tuberculosis
PF Dos Santos, J Van Weyenbergh, M Delgobo, D Oliveira Patricio, ...
The Journal of Immunology 200 (4), 1434-1442, 2018
452018
GlycA, a nuclear magnetic resonance spectroscopy measure for protein glycosylation, is a viable biomarker for disease activity in IBD
T Dierckx, B Verstockt, S Vermeire, J van Weyenbergh
Journal of Crohn's and Colitis 13 (3), 389-394, 2019
432019
Pathogen transcriptional profile in nasopharyngeal aspirates of children with acute respiratory tract infection
KF Fukutani, CM Nascimento-Carvalho, W Van der Gucht, E Wollants, ...
Journal of Clinical Virology 69, 190-196, 2015
282015
IFN-β induces greater antiproliferative and proapoptotic effects and increased p53 signaling compared with IFN-α in PBMCs of Adult T-cell Leukemia/Lymphoma patients
T Dierckx, R Khouri, SM Menezes, D Decanine, L Farre, A Bittencourt, ...
Blood cancer journal 7 (1), e519-e519, 2017
252017
Comprehensive Antiretroviral Restriction Factor Profiling Reveals the Evolutionary Imprint of the ex Vivo and in Vivo IFN-β Response in HTLV-1-Associated …
FE Leal, SM Menezes, EAS Costa, PM Brailey, L Gama, AC Segurado, ...
Frontiers in microbiology 9, 985, 2018
222018
The metabolic fingerprint of COVID-19 severity
T Dierckx, J Van Elslande, H Salmela, B Decru, E Wauters, J Gunst, ...
MedRxiv, 2020.11. 09.20228221, 2020
202020
Detection of natural resistance-associated substitutions by ion semiconductor technology in HCV1b positive, direct-acting antiviral agents-naïve patients
N Marascio, G Pavia, A Strazzulla, T Dierckx, L Cuypers, B Vrancken, ...
International Journal of Molecular Sciences 17 (9), 1416, 2016
202016
A Fashi Lymphoproliferative Phenotype Reveals Non-Apoptotic Fas Signaling in HTLV-1-Associated Neuroinflammation
SM Menezes, FE Leal, T Dierckx, R Khouri, D Decanine, G Silva-Santos, ...
Frontiers in immunology 8, 97, 2017
182017
Decreased RORC expression and downstream signaling in HTLV‐1‐associated adult T‐cell lymphoma/leukemia uncovers an antiproliferative IL17 link: A potential target for …
K Subramanian, T Dierckx, R Khouri, SM Menezes, H Kagdi, GP Taylor, ...
International Journal of Cancer 144 (7), 1664-1675, 2019
172019
In situ Immune Signatures and Microbial Load at the Nasopharyngeal Interface in Children With Acute Respiratory Infection
KF Fukutani, CM Nascimento-Carvalho, ML Bouzas, JR Oliveira, A Barral, ...
Frontiers in Microbiology 9, 2475, 2018
162018
A genetic IFN/STAT1/FAS axis determines CD4 T stem cell memory levels and apoptosis in healthy controls and Adult T-cell Leukemia patients
R Khouri, G Silva-Santos, T Dierckx, SM Menezes, D Decanine, K Theys, ...
Oncoimmunology 7 (5), e1426423, 2018
162018
enAsCas12a enables CRISPR-directed evolution to screen for functional drug resistance mutations in sequences inaccessible to SpCas9
JE Neggers, M Jacquemyn, T Dierckx, BP Kleinstiver, HJ Thibaut, ...
Molecular Therapy 29 (1), 208-224, 2021
142021
Urinary peptides as potential non-invasive biomarkers for lupus nephritis: results of the peptidu-LUP study
M Tailliar, JP Schanstra, T Dierckx, B Breuil, G Hanouna, N Charles, ...
Journal of Clinical Medicine 10 (8), 1690, 2021
132021
Systemic cytokines and GlycA discriminate disease status and predict corticosteroid response in HTLV-1-associated neuroinflammation
T Assone, SM Menezes, F de Toledo Gonçalves, VA Folgosi, ...
Journal of neuroinflammation 19 (1), 293, 2022
122022
Serum GlycA level is elevated in active systemic lupus erythematosus and correlates to disease activity and lupus nephritis severity
T Dierckx, L Chiche, L Daniel, B Lauwerys, J Van Weyenbergh, ...
Journal of clinical medicine 9 (4), 970, 2020
122020
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Articles 1–20