| Neuronal activity enhances tau propagation and tau pathology in vivo JW Wu, SA Hussaini, IM Bastille, GA Rodriguez, A Mrejeru, K Rilett, ... Nature neuroscience 19 (8), 1085-1092, 2016 | 763 | 2016 |
| Tau protein hyperphosphorylation and aggregation in Alzheimer’s disease and other tauopathies, and possible neuroprotective strategies G Šimić, M Babić Leko, S Wray, C Harrington, I Delalle, ... Biomolecules 6 (1), 6, 2016 | 744 | 2016 |
| Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis DP Hanger, HL Byers, S Wray, KY Leung, MJ Saxton, A Seereeram, ... Journal of Biological Chemistry 282 (32), 23645-23654, 2007 | 559 | 2007 |
| The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy VS Burchell, DE Nelson, A Sanchez-Martinez, M Delgado-Camprubi, ... Nature neuroscience 16 (9), 1257-1265, 2013 | 369 | 2013 |
| C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis JD Rohrer, AM Isaacs, S Mizielinska, S Mead, T Lashley, S Wray, K Sidle, ... The Lancet Neurology 14 (3), 291-301, 2015 | 295 | 2015 |
| Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cγ1, Grb2, and Src family kinases CH Reynolds, CJ Garwood, S Wray, C Price, S Kellie, T Perera, ... Journal of Biological Chemistry 283 (26), 18177-18186, 2008 | 294 | 2008 |
| Monoaminergic neuropathology in Alzheimer’s disease G Šimić, MB Leko, S Wray, CR Harrington, I Delalle, N Jovanov-Milošević, ... Progress in neurobiology 151, 101-138, 2017 | 289 | 2017 |
| MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies D Trabzuni, S Wray, J Vandrovcova, A Ramasamy, R Walker, C Smith, ... Human molecular genetics 21 (18), 4094-4103, 2012 | 274 | 2012 |
| The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis K Imamura, Y Izumi, A Watanabe, K Tsukita, K Woltjen, T Yamamoto, ... Science Translational Medicine 9 (391), eaaf3962, 2017 | 261 | 2017 |
| Hallmarks of Alzheimer’s disease in stem-cell-derived human neurons transplanted into mouse brain I Espuny-Camacho, AM Arranz, M Fiers, A Snellinx, K Ando, S Munck, ... Neuron 93 (5), 1066-1081. e8, 2017 | 237 | 2017 |
| G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ... EMBO molecular medicine 10 (1), 22-31, 2018 | 216 | 2018 |
| Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS CE Hall, Z Yao, M Choi, GE Tyzack, A Serio, R Luisier, J Harley, E Preza, ... Cell reports 19 (9), 1739-1749, 2017 | 200 | 2017 |
| Pathogenic VCP mutations induce mitochondrial uncoupling and reduced ATP levels F Bartolome, HC Wu, VS Burchell, E Preza, S Wray, CJ Mahoney, NC Fox, ... Neuron 78 (1), 57-64, 2013 | 180 | 2013 |
| Stem cell models of Alzheimer’s disease: progress and challenges C Arber, C Lovejoy, S Wray Alzheimer's research & therapy 9, 1-17, 2017 | 176 | 2017 |
| Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10+ 16 splice-site mutation in MAPT T Sposito, E Preza, CJ Mahoney, N Setó-Salvia, NS Ryan, HR Morris, ... Human molecular genetics 24 (18), 5260-5269, 2015 | 175 | 2015 |
| Microtubules deform the nuclear membrane and disrupt nucleocytoplasmic transport in tau-mediated frontotemporal dementia F Paonessa, LD Evans, R Solanki, D Larrieu, S Wray, J Hardy, ... Cell reports 26 (3), 582-593. e5, 2019 | 169 | 2019 |
| Complement receptor 1 (CR1) and Alzheimer's disease H Crehan, P Holton, S Wray, J Pocock, R Guerreiro, J Hardy Immunobiology 217 (2), 244-250, 2012 | 148 | 2012 |
| Familial Alzheimer’s disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta C Arber, J Toombs, C Lovejoy, NS Ryan, RW Paterson, N Willumsen, ... Molecular Psychiatry 25 (11), 2919-2931, 2020 | 143 | 2020 |
| Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories CE Arber, A Li, H Houlden, S Wray Neuropathology and applied neurobiology 42 (3), 220-241, 2016 | 136 | 2016 |
| Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+ 16 MAPT mutation leads to oxidative stress and neurodegeneration N Esteras, JD Rohrer, J Hardy, S Wray, AY Abramov Redox biology 12, 410-422, 2017 | 121 | 2017 |
Charles ArberSenior Research Fellow, UCL Institute of NeurologyVerified email at ucl.ac.uk
