| Structural basis for substrate loading in bacterial RNA polymerase DG Vassylyev, MN Vassylyeva, J Zhang, M Palangat, I Artsimovitch, ... Nature 448 (7150), 163-168, 2007 | 424 | 2007 |
| Biochemical and molecular changes at the cellular level in response to exposure to environmental estrogen-like chemicals D Roy, M Palangat, CW Chen, RD Thomas, J Colerangle, A Atkinson, ... Journal of Toxicology and Environmental Health Part A 50 (1), 1-30, 1997 | 288 | 1997 |
| A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing I Toulokhonov, J Zhang, M Palangat, R Landick Molecular cell 27 (3), 406-419, 2007 | 243 | 2007 |
| Kinetic competition during the transcription cycle results in stochastic RNA processing A Coulon, ML Ferguson, V de Turris, M Palangat, CC Chow, DR Larson Elife 3, e03939, 2014 | 221 | 2014 |
| Role of the RNA polymerase trigger loop in catalysis and pausing J Zhang, M Palangat, R Landick Nature structural & molecular biology 17 (1), 99-104, 2010 | 173 | 2010 |
| Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II MH Larson, J Zhou, CD Kaplan, M Palangat, RD Kornberg, R Landick, ... Proceedings of the National Academy of Sciences 109 (17), 6555-6560, 2012 | 164 | 2012 |
| Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection Y Wan, DG Anastasakis, J Rodriguez, M Palangat, P Gudla, G Zaki, ... Cell 184 (11), 2878-2895. e20, 2021 | 154 | 2021 |
| Transcriptional pausing at+ 62 of the HIV-1 nascent RNA modulates formation of the TAR RNA structure M Palangat, TI Meier, RG Keene, R Landick Molecular cell 1 (7), 1033-1042, 1998 | 127 | 1998 |
| Transcriptional bursting and co-bursting regulation by steroid hormone release pattern and transcription factor mobility DA Stavreva, DA Garcia, G Fettweis, PR Gudla, GF Zaki, V Soni, ... Molecular cell 75 (6), 1161-1177. e11, 2019 | 112 | 2019 |
| Roles of RNA: DNA hybrid stability, RNA structure, and active site conformation in pausing by human RNA polymerase II M Palangat, R Landick Journal of molecular biology 311 (2), 265-282, 2001 | 105 | 2001 |
| A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS M Palangat, DB Renner, DH Price, R Landick Proceedings of the National Academy of Sciences 102 (42), 15036-15041, 2005 | 95 | 2005 |
| The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation M Palangat, DG Anastasakis, DL Fei, KE Lindblad, R Bradley, ... Genes & development 33 (9-10), 482-497, 2019 | 90 | 2019 |
| The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription N Malik, H Yan, N Moshkovich, M Palangat, H Yang, V Sanchez, Z Cai, ... Nature communications 10 (1), 2071, 2019 | 79 | 2019 |
| RNA transcript 3′-proximal sequence affects translocation bias of RNA polymerase PP Hein, M Palangat, R Landick Biochemistry 50 (32), 7002-7014, 2011 | 79 | 2011 |
| Direct versus limited-step reconstitution reveals key features of an RNA hairpin-stabilized paused transcription complex S Kyzer, KS Ha, R Landick, M Palangat Journal of Biological Chemistry 282 (26), 19020-19028, 2007 | 54 | 2007 |
| Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase TA Windgassen, RA Mooney, D Nayak, M Palangat, J Zhang, R Landick Nucleic acids research 42 (20), 12707-12721, 2014 | 52 | 2014 |
| Downstream DNA selectively affects a paused conformation of human RNA polymerase II M Palangat, CT Hittinger, R Landick Journal of molecular biology 341 (2), 429-442, 2004 | 46 | 2004 |
| Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II M Palangat, M Larson, X Hu, A Gnatt, S Block, R Landick Transcription 3 (3), 146-153, 2012 | 32 | 2012 |
| Complexity of RNA polymerase II elongation dynamics M Palangat, DR Larson Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1819 (7), 667-672, 2012 | 28 | 2012 |
| The RPB2 flap loop of human RNA polymerase II is dispensable for transcription initiation and elongation M Palangat, JA Grass, MF Langelier, B Coulombe, R Landick Molecular and cellular biology 31 (16), 3312-3325, 2011 | 27 | 2011 |
Daniel R. LarsonNational Cancer InstituteVerified email at nih.gov