CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ... Nature communications 8 (1), 14432, 2017 | 551 | 2017 |
Therapy-induced evolution of human lung cancer revealed by single-cell RNA sequencing A Maynard, CE McCoach, JK Rotow, L Harris, F Haderk, DL Kerr, ... Cell 182 (5), 1232-1251. e22, 2020 | 535 | 2020 |
The p110δ structure: mechanisms for selectivity and potency of new PI (3) K inhibitors A Berndt, S Miller, O Williams, DD Le, BT Houseman, JI Pacold, F Gorrec, ... Nature chemical biology 6 (2), 117-124, 2010 | 355 | 2010 |
G-quadruplex ligands exhibit differential G-tetrad selectivity DD Le, M Di Antonio, LKM Chan, S Balasubramanian Chemical Communications 51 (38), 8048-8050, 2015 | 107 | 2015 |
Human melanocyte development and melanoma dedifferentiation at single-cell resolution RL Belote, D Le, A Maynard, UE Lang, A Sinclair, BK Lohman, ... Nature Cell Biology 23 (9), 1035-1047, 2021 | 101 | 2021 |
Comprehensive, high-resolution binding energy landscapes reveal context dependencies of transcription factor binding DD Le, TC Shimko, AK Aditham, AM Keys, SA Longwell, Y Orenstein, ... Proceedings of the National Academy of Sciences 115 (16), E3702-E3711, 2018 | 90 | 2018 |
Docking and linking of fragments to discover jumonji histone demethylase inhibitors M Korczynska, DD Le, N Younger, E Gregori-Puigjané, A Tumber, ... Journal of medicinal chemistry 59 (4), 1580-1598, 2016 | 60 | 2016 |
Site-specific and regiospecific installation of methylarginine analogues into recombinant histones and insights into effector protein binding DD Le, AT Cortesi, SA Myers, AL Burlingame, DG Fujimori Journal of the American Chemical Society 135 (8), 2879-2882, 2013 | 54 | 2013 |
Potentially crystalline deformation rings and Serre weight conjectures: shapes and shadows D Le, BV Le Hung, B Levin, S Morra Inventiones mathematicae 212, 1-107, 2018 | 46 | 2018 |
Weight elimination in Serre-type conjectures D Le, BV Le Hung, B Levin | 40 | 2019 |
Protein and nucleic acid methylating enzymes: mechanisms and regulation DD Le, DG Fujimori Current opinion in chemical biology 16 (5-6), 507-515, 2012 | 36 | 2012 |
Local models for Galois deformation rings and applications D Le, BVL Hung, B Levin, S Morra Inventiones mathematicae 231 (3), 1277-1488, 2023 | 33 | 2023 |
Association between sexual orientation acceptance and suicidal ideation, substance use, and internalised homophobia amongst the pink carpet Y cohort study of young gay … C Ong, RKJ Tan, D Le, A Tan, A Tyler, C Tan, C Kwok, S Banerjee, ... BMC Public Health 21 (1), 971, 2021 | 33 | 2021 |
Chloride channels regulate differentiation and barrier functions of the mammalian airway M He, B Wu, W Ye, DD Le, AW Sinclair, V Padovano, Y Chen, KX Li, R Sit, ... Elife 9, e53085, 2020 | 32 | 2020 |
On mod in the ordinary case F Herzig, D Le, S Morra Compositio Mathematica 153 (11), 2215-2286, 2017 | 32 | 2017 |
Mental health and Vietnamese children DD Le The psychosocial development of minority group children, 373-384, 1983 | 32 | 1983 |
Experienced homophobia and suicide among young gay, bisexual, transgender, and queer men in Singapore: Exploring the mediating role of depression severity, self-esteem, and … RKJ Tan, TQY Low, D Le, A Tan, A Tyler, C Tan, C Kwok, S Banerjee, ... LGBT health 8 (5), 349-358, 2021 | 30 | 2021 |
Serre weights and Breuil’s lattice conjecture in dimension three D Le, BV Le Hung, B Levin, S Morra Forum of Mathematics, Pi 8, e5, 2020 | 25 | 2020 |
Delineating patterns of sexualized substance use and its association with sexual and mental health outcomes among young gay, bisexual and other men who have sex with men in … RKJ Tan, CA O’Hara, WL Koh, D Le, A Tan, A Tyler, C Tan, C Kwok, ... BMC public health 21, 1-11, 2021 | 24 | 2021 |
Diagrams in the mod p cohomology of Shimura curves A Dotto, D Le Compositio Mathematica 157 (8), 1653-1723, 2021 | 24 | 2021 |