| Genomewide association study of severe Covid-19 with respiratory failure Severe Covid-19 GWAS Group New England Journal of Medicine 383 (16), 1522-1534, 2020 | 2041 | 2020 |
| Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug H Wu, E Esteve, V Tremaroli, MT Khan, R Caesar, L Mannerås-Holm, ... Nature medicine 23 (7), 850-858, 2017 | 1588 | 2017 |
| SNPassoc: an R package to perform whole genome association studies JR González, L Armengol, X Solé, E Guinó, JM Mercader, X Estivill, ... Bioinformatics 23 (5), 654-655, 2007 | 907 | 2007 |
| Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 851 | 2021 |
| A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations K Bønnelykke, P Sleiman, K Nielsen, E Kreiner-Møller, JM Mercader, ... Nature genetics 46 (1), 51-55, 2014 | 688 | 2014 |
| The power of genetic diversity in genome-wide association studies of lipids SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ... Nature 600 (7890), 675-679, 2021 | 657 | 2021 |
| A saturated map of common genetic variants associated with human height L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ... Nature 610 (7933), 704-712, 2022 | 563 | 2022 |
| Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders … M Gratacòs, JR González, JM Mercader, R de Cid, M Urretavizcaya, ... Biological psychiatry 61 (7), 911-922, 2007 | 538 | 2007 |
| Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors NM Warrington, RN Beaumont, M Horikoshi, FR Day, Ø Helgeland, ... Nature genetics 51 (5), 804-814, 2019 | 532 | 2019 |
| Targeting the circulating microRNA signature of obesity FJ Ortega, JM Mercader, V Catalan, JM Moreno-Navarrete, N Pueyo, ... Clinical chemistry 59 (5), 781-792, 2013 | 503 | 2013 |
| Genome-wide associations for birth weight and correlations with adult disease M Horikoshi, RN Beaumont, FR Day, NM Warrington, MN Kooijman, ... Nature 538 (7624), 248-252, 2016 | 498 | 2016 |
| Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ... Nature genetics 54 (5), 560-572, 2022 | 482 | 2022 |
| Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: a soft clustering analysis MS Udler, J Kim, M von Grotthuss, S Bonàs-Guarch, JB Cole, J Chiou, ... PLoS medicine 15 (9), e1002654, 2018 | 476 | 2018 |
| Profiling of circulating microRNAs reveals common microRNAs linked to type 2 diabetes that change with insulin sensitization FJ Ortega, JM Mercader, JM Moreno-Navarrete, O Rovira, E Guerra, ... Diabetes care 37 (5), 1375-1383, 2014 | 427 | 2014 |
| Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls J Flannick, JM Mercader, C Fuchsberger, MS Udler, A Mahajan, J Wessel, ... Nature 570 (7759), 71-76, 2019 | 317 | 2019 |
| Whole-genome sequencing reveals host factors underlying critical COVID-19 A Kousathanas, E Pairo-Castineira, K Rawlik, A Stuckey, CA Odhams, ... Nature 607 (7917), 97-103, 2022 | 310 | 2022 |
| Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population K Estrada, I Aukrust, L Bjørkhaug, NP Burtt, JM Mercader, H García-Ortiz, ... Jama 311 (22), 2305-2314, 2014 | 296 | 2014 |
| Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes I Miguel-Escalada, S Bonàs-Guarch, I Cebola, J Ponsa-Cobas, ... Nature genetics 51 (7), 1137-1148, 2019 | 264 | 2019 |
| Changes in circulating microRNAs are associated with childhood obesity A Prats-Puig, FJ Ortega, JM Mercader, JM Moreno-Navarrete, M Moreno, ... The Journal of Clinical Endocrinology & Metabolism 98 (10), E1655-E1660, 2013 | 249 | 2013 |
| Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes M Imamura, A Takahashi, T Yamauchi, K Hara, K Yasuda, N Grarup, ... Nature communications 7 (1), 10531, 2016 | 203 | 2016 |
Jose C. FlorezProfessor of Medicine, Harvard Medical SchoolVerified email at broadinstitute.org
