| Dysregulation of Wnt/β-catenin signaling in gastrointestinal cancers BD White, AJ Chien, DW Dawson Gastroenterology 142 (2), 219-232, 2012 | 568 | 2012 |
| A Wnt survival guide: from flies to human disease AJ Chien, WH Conrad, RT Moon Journal of Investigative Dermatology 129 (7), 1614-1627, 2009 | 477 | 2009 |
| Activated Wnt/ß-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model AJ Chien, EC Moore, AS Lonsdorf, RM Kulikauskas, BG Rothberg, ... Proceedings of the National Academy of Sciences 106 (4), 1193-1198, 2009 | 447 | 2009 |
| Roles of a membrane-localized βsubunit in the formation and targeting of functional L-type Ca2+ channels AJ Chien, X Zhao, RE Shirokov, TS Puri, CF Chang, D Sun, E Rios, ... Journal of Biological Chemistry 270 (50), 30036-30044, 1995 | 354 | 1995 |
| Identification of palmitoylation sites within the L-type calcium channel β2a subunit and effects on channel function AJ Chien, KM Carr, RE Shirokov, E Rios, MM Hosey Journal of Biological Chemistry 271 (43), 26465-26468, 1996 | 252 | 1996 |
| Identification and subcellular localization of the subunits of L-type calcium channels and adenylyl cyclase in cardiac myocytes T Gao, TS Puri, BL Gerhardstein, AJ Chien, RD Green, MM Hosey Journal of Biological Chemistry 272 (31), 19401-19407, 1997 | 229 | 1997 |
| WNT5A enhances resistance of melanoma cells to targeted BRAF inhibitors JN Anastas, RM Kulikauskas, T Tamir, H Rizos, GV Long, EM Von Euw, ... The Journal of clinical investigation 124 (7), 2877-2890, 2014 | 226 | 2014 |
| Identification of the Sites Phosphorylated by Cyclic AMP-Dependent Protein Kinase on the β2 Subunit of L-Type Voltage-Dependent Calcium Channels† BL Gerhardstein, TS Puri, AJ Chien, MM Hosey Biochemistry 38 (32), 10361-10370, 1999 | 224 | 1999 |
| Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma TL Biechele, RM Kulikauskas, RA Toroni, OM Lucero, RD Swift, ... Science signaling 5 (206), ra3-ra3, 2012 | 199 | 2012 |
| Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis SL Lai, AJ Chien, RT Moon Cell research 19 (5), 532-545, 2009 | 194 | 2009 |
| New regulators of Wnt/β-catenin signaling revealed by integrative molecular screening MB Major, BS Roberts, JD Berndt, S Marine, J Anastas, N Chung, ... Science signaling 1 (45), ra12-ra12, 2008 | 175 | 2008 |
| Complexes of the α1C and β subunits generate the necessary signal for membrane targeting of class C L-type calcium channels T Gao, AJ Chien, MM Hosey Journal of Biological Chemistry 274 (4), 2137-2144, 1999 | 168 | 1999 |
| Membrane targeting of L-type calcium channels: role of palmitoylation in the subcellular localization of the β2a subunit AJ Chien, T Gao, E Perez-Reyes, MM Hosey Journal of Biological Chemistry 273 (36), 23590-23597, 1998 | 162 | 1998 |
| A re-evaluation of the “oncogenic” nature of Wnt/β-catenin signaling in melanoma and other cancers OM Lucero, DW Dawson, RT Moon, AJ Chien Current oncology reports 12, 314-318, 2010 | 154 | 2010 |
| Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels MB Meyers, TS Puri, AJ Chien, T Gao, PH Hsu, MM Hosey, GI Fishman Journal of Biological Chemistry 273 (30), 18930-18935, 1998 | 149 | 1998 |
| WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma MD Arensman, AN Kovochich, RM Kulikauskas, AR Lay, PT Yang, X Li, ... Oncogene 33 (7), 899-908, 2014 | 137 | 2014 |
| Targeting Wnt pathways in disease ZF Zimmerman, RT Moon, AJ Chien Cold Spring Harbor perspectives in biology 4 (11), a008086, 2012 | 132 | 2012 |
| CTLA-4 Is a Direct Target of Wnt/β-Catenin Signaling and Is Expressed in Human Melanoma Tumors KV Shah, AJ Chien, C Yee, RT Moon Journal of Investigative Dermatology 128 (12), 2870-2879, 2008 | 106 | 2008 |
| WNTS and WNT receptors as therapeutic tools and targets in human disease processes AJ Chien, RT Moon Frontiers in bioscience: a journal and virtual library 12, 448, 2007 | 103 | 2007 |
| Activation of Wnt/β-catenin signaling increases apoptosis in melanoma cells treated with trail ZF Zimmerman, RM Kulikauskas, K Bomsztyk, RT Moon, AJ Chien PloS one 8 (7), e69593, 2013 | 95 | 2013 |
Randall MoonDepartment of Pharmacology Univ. of WashingtonVerified email at uw.edu
