| Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss JI Aguirre, LI Plotkin, SA Stewart, RS Weinstein, AM Parfitt, SC Manolagas, ... Journal of bone and mineral research 21 (4), 605-615, 2006 | 663 | 2006 |
| Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs LI Plotkin, I Mathov, JI Aguirre, AM Parfitt, SC Manolagas, T Bellido American Journal of Physiology-Cell Physiology 289 (3), C633-C643, 2005 | 339 | 2005 |
| Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation LI Plotkin, JI Aguirre, S Kousteni, SC Manolagas, T Bellido Journal of Biological Chemistry 280 (8), 7317-7325, 2005 | 321 | 2005 |
| Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and … J Aguirre, L Buttery, M O’Shaughnessy, F Afzal, IF de Marticorena, ... The American journal of pathology 158 (1), 247-257, 2001 | 283 | 2001 |
| Transient versus sustained phosphorylation and nuclear accumulation of ERKs underlie anti-versus pro-apoptotic effects of estrogens JR Chen, LI Plotkin, JI Aguirre, L Han, RL Jilka, S Kousteni, T Bellido, ... Journal of biological chemistry 280 (6), 4632-4638, 2005 | 217 | 2005 |
| Oncologic doses of zoledronic acid induce osteonecrosis of the jaw‐like lesions in rice rats (Oryzomys palustris) with periodontitis JI Aguirre, MP Akhter, DB Kimmel, JE Pingel, A Williams, M Jorgensen, ... Journal of Bone and Mineral Research 27 (10), 2130-2143, 2012 | 178 | 2012 |
| A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction JI Aguirre, LI Plotkin, AR Gortazar, MM Millan, CA O'Brien, SC Manolagas, ... Journal of Biological Chemistry 282 (35), 25501-25508, 2007 | 175 | 2007 |
| Effects of alendronate on bone healing after tooth extraction in rats JI Aguirre, MK Altman, SM Vanegas, SE Franz, ACF Bassit, TJ Wronski Oral diseases 16 (7), 674-685, 2010 | 113 | 2010 |
| Sepsis clinical criteria in emergency department patients admitted to an intensive care unit: an external validation study of quick sequential organ failure assessment MD April, J Aguirre, LI Tannenbaum, T Moore, A Pingree, RE Thaxton, ... The Journal of emergency medicine 52 (5), 622-631, 2017 | 112 | 2017 |
| Time-dependent cellular and transcriptional changes in the osteoblast lineage associated with sclerostin antibody treatment in ovariectomized rats S Taylor, MS Ominsky, R Hu, E Pacheco, YD He, DL Brown, JI Aguirre, ... Bone 84, 148-159, 2016 | 99 | 2016 |
| Differential temporal effects of sclerostin antibody and parathyroid hormone on cancellous and cortical bone and quantitative differences in effects on the osteoblast lineage … MS Ominsky, DL Brown, G Van, D Cordover, E Pacheco, E Frazier, ... Bone 81, 380-391, 2015 | 93 | 2015 |
| Vascular remodeling and ET-1 expression in rat strains with different responses to chronic hypoxia JI Aguirre, NW Morrell, L Long, P Clift, PD Upton, JM Polak, MR Wilkins American Journal of Physiology-Lung Cellular and Molecular Physiology 278 (5 …, 2000 | 78 | 2000 |
| Preclinical models of medication-related osteonecrosis of the jaw (MRONJ) JI Aguirre, EJ Castillo, DB Kimmel Bone 153, 116184, 2021 | 73 | 2021 |
| Role for β1 integrins in cortical osteocytes during acute musculoskeletal disuse JA Phillips, EAC Almeida, EL Hill, JI Aguirre, MF Rivera, I Nachbandi, ... Matrix Biology 27 (7), 609-618, 2008 | 66 | 2008 |
| Exosomes: novel regulators of bone remodelling and potential therapeutic agents for orthodontics LS Holliday, KP McHugh, J Zuo, JI Aguirre, JK Neubert, WJ Rody Jr Orthodontics & craniofacial research 20, 95-99, 2017 | 64 | 2017 |
| Sclerostin inhibition prevents spinal cord injury‐induced cancellous bone loss LA Beggs, F Ye, P Ghosh, DT Beck, CF Conover, A Balaez, JR Miller, ... Journal of Bone and Mineral Research 30 (4), 681-689, 2015 | 64 | 2015 |
| Testosterone dose dependently prevents bone and muscle loss in rodents after spinal cord injury JF Yarrow, CF Conover, LA Beggs, DT Beck, DM Otzel, A Balaez, ... Journal of neurotrauma 31 (9), 834-845, 2014 | 61 | 2014 |
| Ectopic expression of Wnt10b decreases adiposity and improves glucose homeostasis in obese rats G Aslanidi, V Kroutov, G Philipsberg, K Lamb, M Campbell-Thompson, ... American Journal of Physiology-Endocrinology and Metabolism 293 (3), E726-E736, 2007 | 56 | 2007 |
| Antibiotic perturbation of gut microbiota dysregulates osteoimmune cross talk in postpubertal skeletal development JD Hathaway-Schrader, HM Steinkamp, MB Chavez, NA Poulides, ... The American journal of pathology 189 (2), 370-390, 2019 | 52 | 2019 |
| Biologic and pathologic aspects of osteocytes in the setting of medication-related osteonecrosis of the jaw (MRONJ) JI Aguirre, EJ Castillo, DB Kimmel Bone 153, 116168, 2021 | 45 | 2021 |
Stavros ManolagasDistinguished Professor of Medicine, UAMSVerified email at uams.edu