Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10927 | 2021 |
Guidelines for the use and interpretation of assays for monitoring autophagy 1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... Autophagy 17 (1), 1-382, 2021 | 2862* | 2021 |
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ... The Lancet Neurology 18 (12), 1091-1102, 2019 | 1836 | 2019 |
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin E Greggio, S Jain, A Kingsbury, R Bandopadhyay, P Lewis, A Kaganovich, ... Neurobiology of disease 23 (2), 329-341, 2006 | 861 | 2006 |
Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences C Manzoni, DA Kia, J Vandrovcova, J Hardy, NW Wood, PA Lewis, ... Briefings in bioinformatics 19 (2), 286-302, 2018 | 804 | 2018 |
Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus MJ Devine, M Ryten, P Vodicka, AJ Thomson, T Burdon, H Houlden, ... Nature communications 2 (1), 440, 2011 | 557 | 2011 |
α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson’s disease and multiple system atrophy? AP Kiely, YT Asi, E Kara, P Limousin, H Ling, P Lewis, C Proukakis, ... Acta neuropathologica 125, 753-769, 2013 | 533 | 2013 |
The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation E Greggio, I Zambrano, A Kaganovich, A Beilina, JM Taymans, V Daniëls, ... Journal of Biological Chemistry 283 (24), 16906-16914, 2008 | 379 | 2008 |
The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy VS Burchell, DE Nelson, A Sanchez-Martinez, M Delgado-Camprubi, ... Nature neuroscience 16 (9), 1257-1265, 2013 | 369 | 2013 |
The R1441C mutation of LRRK2 disrupts GTP hydrolysis PA Lewis, E Greggio, A Beilina, S Jain, A Baker, MR Cookson Biochemical and biophysical research communications 357 (3), 668-671, 2007 | 357 | 2007 |
Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase J Deng, PA Lewis, E Greggio, E Sluch, A Beilina, MR Cookson Proceedings of the National Academy of Sciences 105 (5), 1499-1504, 2008 | 289 | 2008 |
The genetics of Parkinson's syndromes: a critical review J Hardy, P Lewis, T Revesz, A Lees, C Paisan-Ruiz Current opinion in genetics & development 19 (3), 254-265, 2009 | 283 | 2009 |
Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 281* | 2016 |
DYT16, a novel young-onset dystonia-parkinsonism disorder: identification of a segregating mutation in the stress-response protein PRKRA S Camargos, S Scholz, J Simón-Sánchez, C Paisán-Ruiz, P Lewis, ... The Lancet Neurology 7 (3), 207-215, 2008 | 264 | 2008 |
Genetic and phenotypic characterization of complex hereditary spastic paraplegia E Kara, A Tucci, C Manzoni, DS Lynch, M Elpidorou, C Bettencourt, ... Brain 139 (7), 1904-1918, 2016 | 227 | 2016 |
Cancer and neurodegeneration: between the devil and the deep blue sea H Plun-Favreau, PA Lewis, J Hardy, LM Martins, NW Wood PLoS Genet 6 (12), e1001257, 2010 | 193 | 2010 |
Guidelines for the use and interpretation of assays for monitoring autophagy HP Spaink, HP Spaink Autophagy 12 (1), 1-222, 2016 | 188* | 2016 |
Inhibition of LRRK2 kinase activity stimulates macroautophagy C Manzoni, A Mamais, S Dihanich, R Abeti, MPM Soutar, H Plun-Favreau, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (12), 2900-2910, 2013 | 179 | 2013 |
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages A Härtlova, S Herbst, J Peltier, A Rodgers, O Bilkei‐Gorzo, A Fearns, ... The EMBO journal 37 (12), e98694, 2018 | 178 | 2018 |
Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS‐1 mutations that lead to exceptionally high amyloid‐β concentrations H Houlden, M Baker, E McGowan, P Lewis, M Hutton, R Crook, NW Wood, ... Annals of neurology 48 (5), 806-808, 2000 | 176 | 2000 |