Ocular surface wetness is regulated by TRPM8-dependent cold thermoreceptors of the cornea A Parra, R Madrid, D Echevarria, S Del Olmo, C Morenilla-Palao, ... Nature medicine 16 (12), 1396-1399, 2010 | 348 | 2010 |
Variable threshold of trigeminal cold-thermosensitive neurons is determined by a balance between TRPM8 and Kv1 potassium channels R Madrid, E De La Peña, T Donovan-Rodriguez, C Belmonte, F Viana Journal of Neuroscience 29 (10), 3120-3131, 2009 | 218 | 2009 |
Contribution of TRPM8 channels to cold transduction in primary sensory neurons and peripheral nerve terminals R Madrid, T Donovan-Rodríguez, V Meseguer, MC Acosta, C Belmonte, ... Journal of Neuroscience 26 (48), 12512-12525, 2006 | 209 | 2006 |
Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability E Fritz, P Izaurieta, A Weiss, FR Mir, P Rojas, D Gonzalez, F Rojas, ... Journal of neurophysiology 109 (11), 2803-2814, 2013 | 134 | 2013 |
N-glycosylation of TRPM8 ion channels modulates temperature sensitivity of cold thermoreceptor neurons M Pertusa, R Madrid, C Morenilla-Palao, C Belmonte, F Viana Journal of Biological Chemistry 287 (22), 18218-18229, 2012 | 96 | 2012 |
A cool channel in cold transduction R Latorre, S Brauchi, R Madrid, P Orio Physiology 26 (4), 273-285, 2011 | 93 | 2011 |
Characteristics and physiological role of hyperpolarization activated currents in mouse cold thermoreceptors P Orio, R Madrid, E De La Peña, A Parra, V Meseguer, DA Bayliss, ... The Journal of physiology 587 (9), 1961-1976, 2009 | 69 | 2009 |
A Transient Receptor Potential Ion Channel in Chlamydomonas Shares Key Features with Sensory Transduction-Associated TRP Channels in Mammals L Arias-Darraz, D Cabezas, CK Colenso, M Alegría-Arcos, ... The Plant Cell 27 (1), 177-188, 2015 | 65 | 2015 |
Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons C Arredondo, C Cefaliello, A Dyrda, N Jury, P Martinez, I Díaz, A Amaro, ... Neuron 110 (10), 1656-1670. e12, 2022 | 62 | 2022 |
Role of TRPM8 channels in altered cold sensitivity of corneal primary sensory neurons induced by axonal damage R Piña, G Ugarte, M Campos, A Íñigo-Portugués, E Olivares, P Orio, ... Journal of Neuroscience 39 (41), 8177-8192, 2019 | 53 | 2019 |
Targeted overexpression of tumor necrosis factor-α increases cyclin-dependent kinase 5 activity and TRPV1-dependent Ca2+ influx in trigeminal neurons P Rozas, P Lazcano, R Piña, A Cho, A Terse, M Pertusa, R Madrid, ... Pain 157 (6), 1346-1362, 2016 | 49 | 2016 |
Role of the excitability brake potassium current IKD in cold allodynia induced by chronic peripheral nerve injury A González, G Ugarte, C Restrepo, G Herrera, R Piña, ... Journal of Neuroscience 37 (12), 3109-3126, 2017 | 47 | 2017 |
Role of Ih in the firing pattern of mammalian cold thermoreceptor endings P Orio, A Parra, R Madrid, O González, C Belmonte, F Viana Journal of neurophysiology 108 (11), 3009-3023, 2012 | 42 | 2012 |
Critical role of the pore domain in the cold response of TRPM8 channels identified by ortholog functional comparison M Pertusa, B Rivera, A González, G Ugarte, R Madrid Journal of Biological Chemistry 293 (32), 12454-12471, 2018 | 40 | 2018 |
Calcium mediates the activation of the inhibitory current induced by odorants in toad olfactory receptor neurons B Morales, R Madrid, J Bacigalupo FEBS letters 402 (2-3), 259-264, 1997 | 36 | 1997 |
Bidirectional modulation of thermal and chemical sensitivity of TRPM8 channels by the initial region of the N-terminal domain M Pertusa, A Gonzalez, P Hardy, R Madrid, F Viana Journal of Biological Chemistry 289 (32), 21828-21843, 2014 | 34 | 2014 |
TRPM8-dependent dynamic response in a mathematical model of cold thermoreceptor E Olivares, S Salgado, JP Maidana, G Herrera, M Campos, R Madrid, ... PloS one 10 (10), e0139314, 2015 | 29 | 2015 |
Tonic and phasic receptor neurons in the vertebrate olfactory epithelium R Madrid, M Sanhueza, O Alvarez, J Bacigalupo Biophysical journal 84 (6), 4167-4181, 2003 | 25 | 2003 |
Intimacies and physiological role of the polymodal cold-sensitive ion channel TRPM8 R Madrid, M Pertusa Current topics in membranes 74, 293-324, 2014 | 23 | 2014 |
Non-conventional axonal organelles control TRPM8 ion channel trafficking and peripheral cold sensing VH Cornejo, C Gonzalez, M Campos, L Vargas-Saturno, ... Cell Reports 30 (13), 4505-4517. e5, 2020 | 20 | 2020 |