A combinatorial library of lipid-like materials for delivery of RNAi therapeutics A Akinc, A Zumbuehl, M Goldberg, ES Leshchiner, V Busini, N Hossain, ... Nature biotechnology 26 (5), 561-569, 2008 | 1497 | 2008 |
Reprogramming human T cell function and specificity with non-viral genome targeting TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ... Nature 559 (7714), 405-409, 2018 | 873 | 2018 |
Polymeric materials for gene delivery and DNA vaccination DN Nguyen, JJ Green, JM Chan, R Langer, DG Anderson Advanced Materials 21 (8), 847-867, 2009 | 349 | 2009 |
Molecularly engineered poly (ortho ester) microspheres for enhanced delivery of DNA vaccines C Wang, Q Ge, D Ting, D Nguyen, HR Shen, J Chen, HN Eisen, J Heller, ... Nature Materials 3 (3), 190-196, 2004 | 321 | 2004 |
Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency DN Nguyen, TL Roth, PJ Li, PA Chen, R Apathy, MR Mamedov, LT Vo, ... Nature Biotechnology 38 (1), 44-49, 2020 | 285 | 2020 |
Test performance evaluation of SARS-CoV-2 serological assays JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ... Nature biotechnology 38 (10), 1174, 2020 | 267 | 2020 |
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ... Nature biotechnology 38 (10), 1174-1183, 2020 | 263 | 2020 |
SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood DL Ng, GM Goldgof, BR Shy, AG Levine, J Balcerek, SP Bapat, J Prostko, ... Nature Communications 11 (1), 1-7, 2020 | 199 | 2020 |
Pooled knockin targeting for genome engineering of cellular immunotherapies TL Roth, PJ Li, F Blaeschke, JF Nies, R Apathy, C Mowery, R Yu, ... Cell 181 (3), 728-744. e21, 2020 | 187 | 2020 |
Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering JR Hamilton, CA Tsuchida, DN Nguyen, BR Shy, ER McGarrigle, ... Cell reports 35 (9), 2021 | 148 | 2021 |
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails BR Shy, VS Vykunta, A Ha, A Talbot, TL Roth, DN Nguyen, WG Pfeifer, ... Nature biotechnology 41 (4), 521-531, 2023 | 142 | 2023 |
Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery DN Nguyen, KP Mahon, G Chikh, P Kim, H Chung, AP Vicari, KT Love, ... Proceedings of the National Academy of Sciences 109 (14), E797-E803, 2012 | 133 | 2012 |
Small molecule end group of linear polymer determines cell-type gene delivery efficacy J Sunshine, JJ Green, KP Mahon, F Yang, AA Eltoukhy, DN Nguyen, ... Advanced materials (Deerfield Beach, Fla.) 21 (48), 4947, 2009 | 131 | 2009 |
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair B Wienert, DN Nguyen, A Guenther, SJ Feng, MN Locke, SK Wyman, ... Nature communications 11 (1), 2109, 2020 | 112 | 2020 |
Drug delivery–mediated control of RNA immunostimulation DN Nguyen, SCY Chen, J Lu, M Goldberg, P Kim, A Sprague, ... Molecular Therapy 17 (9), 1555-1562, 2009 | 108 | 2009 |
XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment Y Lee, D Bogdanoff, Y Wang, GC Hartoularos, JM Woo, CT Mowery, ... Science advances 7 (17), eabg4755, 2021 | 104 | 2021 |
Modulation of the immune response DHN Nguyen, DG Anderson, RS Langer, KP Mahon US Patent App. 13/126,260, 2012 | 93 | 2012 |
A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood DL Ng, AC Granados, YA Santos, V Servellita, GM Goldgof, C Meydan, ... Science advances 7 (6), eabe5984, 2021 | 92 | 2021 |
A novel high‐throughput cell‐based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery DN Nguyen, P Kim, L Martínez‐Sobrido, B Beitzel, A García‐Sastre, ... Biotechnology and bioengineering 103 (4), 664-675, 2009 | 81 | 2009 |
Functional CRISPR dissection of gene networks controlling human regulatory T cell identity K Schumann, SS Raju, M Lauber, S Kolb, E Shifrut, JT Cortez, N Skartsis, ... Nature Immunology 21 (11), 1456-1466, 2020 | 80 | 2020 |