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David Nguyen
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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
A Akinc, A Zumbuehl, M Goldberg, ES Leshchiner, V Busini, N Hossain, ...
Nature biotechnology 26 (5), 561-569, 2008
14972008
Reprogramming human T cell function and specificity with non-viral genome targeting
TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ...
Nature 559 (7714), 405-409, 2018
8732018
Polymeric materials for gene delivery and DNA vaccination
DN Nguyen, JJ Green, JM Chan, R Langer, DG Anderson
Advanced Materials 21 (8), 847-867, 2009
3492009
Molecularly engineered poly (ortho ester) microspheres for enhanced delivery of DNA vaccines
C Wang, Q Ge, D Ting, D Nguyen, HR Shen, J Chen, HN Eisen, J Heller, ...
Nature Materials 3 (3), 190-196, 2004
3212004
Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency
DN Nguyen, TL Roth, PJ Li, PA Chen, R Apathy, MR Mamedov, LT Vo, ...
Nature Biotechnology 38 (1), 44-49, 2020
2852020
Test performance evaluation of SARS-CoV-2 serological assays
JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ...
Nature biotechnology 38 (10), 1174, 2020
2672020
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance
JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ...
Nature biotechnology 38 (10), 1174-1183, 2020
2632020
SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
DL Ng, GM Goldgof, BR Shy, AG Levine, J Balcerek, SP Bapat, J Prostko, ...
Nature Communications 11 (1), 1-7, 2020
1992020
Pooled knockin targeting for genome engineering of cellular immunotherapies
TL Roth, PJ Li, F Blaeschke, JF Nies, R Apathy, C Mowery, R Yu, ...
Cell 181 (3), 728-744. e21, 2020
1872020
Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering
JR Hamilton, CA Tsuchida, DN Nguyen, BR Shy, ER McGarrigle, ...
Cell reports 35 (9), 2021
1482021
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails
BR Shy, VS Vykunta, A Ha, A Talbot, TL Roth, DN Nguyen, WG Pfeifer, ...
Nature biotechnology 41 (4), 521-531, 2023
1422023
Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery
DN Nguyen, KP Mahon, G Chikh, P Kim, H Chung, AP Vicari, KT Love, ...
Proceedings of the National Academy of Sciences 109 (14), E797-E803, 2012
1332012
Small molecule end group of linear polymer determines cell-type gene delivery efficacy
J Sunshine, JJ Green, KP Mahon, F Yang, AA Eltoukhy, DN Nguyen, ...
Advanced materials (Deerfield Beach, Fla.) 21 (48), 4947, 2009
1312009
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair
B Wienert, DN Nguyen, A Guenther, SJ Feng, MN Locke, SK Wyman, ...
Nature communications 11 (1), 2109, 2020
1122020
Drug delivery–mediated control of RNA immunostimulation
DN Nguyen, SCY Chen, J Lu, M Goldberg, P Kim, A Sprague, ...
Molecular Therapy 17 (9), 1555-1562, 2009
1082009
XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment
Y Lee, D Bogdanoff, Y Wang, GC Hartoularos, JM Woo, CT Mowery, ...
Science advances 7 (17), eabg4755, 2021
1042021
Modulation of the immune response
DHN Nguyen, DG Anderson, RS Langer, KP Mahon
US Patent App. 13/126,260, 2012
932012
A diagnostic host response biosignature for COVID-19 from RNA profiling of nasal swabs and blood
DL Ng, AC Granados, YA Santos, V Servellita, GM Goldgof, C Meydan, ...
Science advances 7 (6), eabe5984, 2021
922021
A novel high‐throughput cell‐based method for integrated quantification of type I interferons and in vitro screening of immunostimulatory RNA drug delivery
DN Nguyen, P Kim, L Martínez‐Sobrido, B Beitzel, A García‐Sastre, ...
Biotechnology and bioengineering 103 (4), 664-675, 2009
812009
Functional CRISPR dissection of gene networks controlling human regulatory T cell identity
K Schumann, SS Raju, M Lauber, S Kolb, E Shifrut, JT Cortez, N Skartsis, ...
Nature Immunology 21 (11), 1456-1466, 2020
802020
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