| Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist EYT Chien, W Liu, Q Zhao, V Katritch, G Won Han, MA Hanson, L Shi, ... Science 330 (6007), 1091-1095, 2010 | 1358 | 2010 |
| Activation of the β2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6 JA Ballesteros, AD Jensen, G Liapakis, SGF Rasmussen, L Shi, U Gether, ... Journal of Biological Chemistry 276 (31), 29171-29177, 2001 | 829 | 2001 |
| Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors JA Ballesteros, L Shi, JA Javitch Molecular Pharmacology 60 (1), 1-19, 2001 | 539 | 2001 |
| β2 adrenergic receptor activation: Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch L Shi, G Liapakis, R Xu, F Guarnieri, JA Ballesteros, JA Javitch Journal of Biological Chemistry 277 (43), 40989-40996, 2002 | 506 | 2002 |
| Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism C Saunders, JV Ferrer, L Shi, J Chen, G Merrill, ME Lamb, ... Proceedings of the National Academy of Sciences 97 (12), 6850-6855, 2000 | 480 | 2000 |
| The mechanism of a neurotransmitter: sodium symporter—inward release of Na+ and substrate is triggered by substrate in a second binding site L Shi, M Quick, Y Zhao, H Weinstein, JA Javitch Molecular cell 30 (6), 667-677, 2008 | 430 | 2008 |
| The binding sites for cocaine and dopamine in the dopamine transporter overlap T Beuming, J Kniazeff, ML Bergmann, L Shi, L Gracia, K Raniszewska, ... Nature neuroscience 11 (7), 780-789, 2008 | 424 | 2008 |
| The binding site of aminergic G protein–coupled receptors: the transmembrane segments and second extracellular loop L Shi, JA Javitch Annual review of pharmacology and toxicology 42 (1), 437-467, 2002 | 402 | 2002 |
| Dopamine D2 receptors form higher order oligomers at physiological expression levels W Guo, E Urizar, M Kralikova, JC Mobarec, L Shi, M Filizola, JA Javitch The EMBO journal 27 (17), 2293-2304, 2008 | 380 | 2008 |
| SNOSID, a proteomic method for identification of cysteine S-nitrosylation sites in complex protein mixtures G Hao, B Derakhshan, L Shi, F Campagne, SS Gross Proceedings of the National Academy of Sciences 103 (4), 1012-1017, 2006 | 378 | 2006 |
| The fourth transmembrane segment forms the interface of the dopamine D2 receptor homodimer W Guo, L Shi, JA Javitch Journal of Biological Chemistry 278 (7), 4385-4388, 2003 | 346 | 2003 |
| Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment I Kufareva, M Rueda, V Katritch, RC Stevens, R Abagyan Structure 19 (8), 1108-1126, 2011 | 343 | 2011 |
| A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and … T Beuming, L Shi, JA Javitch, H Weinstein Molecular pharmacology 70 (5), 1630-1642, 2006 | 325 | 2006 |
| Crosstalk in G protein-coupled receptors: changes at the transmembrane homodimer interface determine activation W Guo, L Shi, M Filizola, H Weinstein, JA Javitch Proceedings of the National Academy of Sciences 102 (48), 17495-17500, 2005 | 321 | 2005 |
| Single-molecule dynamics of gating in a neurotransmitter transporter homologue Y Zhao, D Terry, L Shi, H Weinstein, SC Blanchard, JA Javitch Nature 465 (7295), 188-193, 2010 | 282 | 2010 |
| Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue Y Zhao, DS Terry, L Shi, M Quick, H Weinstein, SC Blanchard, JA Javitch Nature 474 (7349), 109-113, 2011 | 256 | 2011 |
| The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice L Shi, JA Javitch Proceedings of the National Academy of Sciences 101 (2), 440-445, 2004 | 249 | 2004 |
| Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells S Pei, M Minhajuddin, KP Callahan, M Balys, JM Ashton, SJ Neering, ... Journal of Biological Chemistry 288 (47), 33542-33558, 2013 | 229 | 2013 |
| Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter: sodium symporters DP Claxton, M Quick, L Shi, FD De Carvalho, H Weinstein, JA Javitch, ... Nature structural & molecular biology 17 (7), 822-829, 2010 | 204 | 2010 |
| Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation M Quick, AML Winther, L Shi, P Nissen, H Weinstein, JA Javitch Proceedings of the National Academy of Sciences 106 (14), 5563-5568, 2009 | 194 | 2009 |
Jonathan JavitchVerified email at cumc.columbia.edu