| A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? L Salmena, L Poliseno, Y Tay, L Kats, PP Pandolfi cell 146 (3), 353-358, 2011 | 6857 | 2011 |
| A coding-independent function of gene and pseudogene mRNAs regulates tumour biology L Poliseno, L Salmena, J Zhang, B Carver, WJ Haveman, PP Pandolfi Nature 465 (7301), 1033-1038, 2010 | 2748 | 2010 |
| The functions and regulation of the PTEN tumour suppressor MS Song, L Salmena, PP Pandolfi Nature reviews Molecular cell biology 13 (5), 283-296, 2012 | 2339 | 2012 |
| Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer A Carracedo, L Ma, J Teruya-Feldstein, F Rojo, L Salmena, A Alimonti, ... The Journal of clinical investigation 118 (9), 3065-3074, 2008 | 1683 | 2008 |
| Tenets of PTEN tumor suppression L Salmena, A Carracedo, PP Pandolfi Cell 133 (3), 403-414, 2008 | 1332 | 2008 |
| Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs Y Tay, L Kats, L Salmena, D Weiss, SM Tan, U Ala, F Karreth, L Poliseno, ... Cell 147 (2), 344-357, 2011 | 1125 | 2011 |
| Subtle variations in Pten dose determine cancer susceptibility A Alimonti, A Carracedo, JG Clohessy, LC Trotman, C Nardella, A Egia, ... Nature genetics 42 (5), 454-458, 2010 | 689 | 2010 |
| The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network MS Song, L Salmena, A Carracedo, A Egia, F Lo-Coco, ... Nature 455 (7214), 813-817, 2008 | 636 | 2008 |
| Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity L Salmena, B Lemmers, A Hakem, E Matysiak-Zablocki, K Murakami, ... Genes & development 17 (7), 883-895, 2003 | 594 | 2003 |
| Identification of the miR-106b~25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation L Poliseno, L Salmena, L Riccardi, A Fornari, MS Song, RM Hobbs, ... Science signaling 3 (117), ra29-ra29, 2010 | 554 | 2010 |
| Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling C Gewinner, ZC Wang, A Richardson, J Teruya-Feldstein, ... Cancer cell 16 (2), 115-125, 2009 | 536 | 2009 |
| Requirement for caspase-8 in NF-κB activation by antigen receptor H Su, N Bidère, L Zheng, A Cubre, K Sakai, J Dale, L Salmena, R Hakem, ... Science 307 (5714), 1465-1468, 2005 | 535 | 2005 |
| High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia A Gutierrez, T Sanda, R Grebliunaite, A Carracedo, L Salmena, Y Ahn, ... Blood, The Journal of the American Society of Hematology 114 (3), 647-650, 2009 | 514 | 2009 |
| Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner MS Song, A Carracedo, L Salmena, SJ Song, A Egia, M Malumbres, ... Cell 144 (2), 187-199, 2011 | 455 | 2011 |
| Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function A Papa, L Wan, M Bonora, L Salmena, MS Song, RM Hobbs, A Lunardi, ... Cell 157 (3), 595-610, 2014 | 318 | 2014 |
| Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity JP McPherson, L Tamblyn, A Elia, E Migon, A Shehabeldin, ... The EMBO journal 23 (18), 3677-3688, 2004 | 227 | 2004 |
| Essential role for caspase-8 in Toll-like receptors and NFκB signaling B Lemmers, L Salmena, N Bidere, H Su, E Matysiak-Zablocki, K Murakami, ... Journal of Biological Chemistry 282 (10), 7416-7423, 2007 | 207 | 2007 |
| Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers J Kotsopoulos, J Lubinski, L Salmena, HT Lynch, C Kim-Sing, ... Breast cancer research 14, 1-7, 2012 | 186 | 2012 |
| A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer A Lunardi, U Ala, MT Epping, L Salmena, JG Clohessy, KA Webster, ... Nature genetics 45 (7), 747-755, 2013 | 172 | 2013 |
| Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD C Berube, LM Boucher, W Ma, A Wakeham, L Salmena, R Hakem, ... Proceedings of the National Academy of Sciences 102 (40), 14314-14320, 2005 | 149 | 2005 |
Pier Paolo PandolfiDirector, Cancer Center and Cancer Research Institute, Beth Israel Deaconess Medical CenterVerified email at bidmc.harvard.edu