| XPB, a subunit of TFIIH, is a target of the natural product triptolide DV Titov, B Gilman, QL He, S Bhat, WK Low, Y Dang, M Smeaton, ... Nature chemical biology 7 (3), 182-188, 2011 | 508 | 2011 |
| Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio DV Titov, V Cracan, RP Goodman, J Peng, Z Grabarek, VK Mootha Science 352 (6282), 231-235, 2016 | 401 | 2016 |
| Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell E Mick, DV Titov, OS Skinner, R Sharma, AA Jourdain, VK Mootha elife 9, e49178, 2020 | 189 | 2020 |
| A cellular mechanism to detect and alleviate reductive stress AG Manford, F Rodríguez-Pérez, KY Shih, Z Shi, CA Berdan, M Choe, ... Cell 183 (1), 46-61. e21, 2020 | 131 | 2020 |
| Homozygous deletion in MICU1 presenting with fatigue and lethargy in childhood D Lewis-Smith, KJ Kamer, H Griffin, AM Childs, K Pysden, D Titov, J Duff, ... Neurology: Genetics 2 (2), e59, 2016 | 110 | 2016 |
| Analyzing protein kinase dynamics in living cells with FRET reporters Q Ni, DV Titov, J Zhang Methods 40 (3), 279-286, 2006 | 103 | 2006 |
| Physical bioenergetics: Energy fluxes, budgets, and constraints in cells X Yang, M Heinemann, J Howard, G Huber, S Iyer-Biswas, G Le Treut, ... Proceedings of the National Academy of Sciences 118 (26), e2026786118, 2021 | 101 | 2021 |
| A genetically encoded tool for manipulation of NADP+/NADPH in living cells V Cracan, DV Titov, H Shen, Z Grabarek, VK Mootha Nature chemical biology 13 (10), 1088-1095, 2017 | 99 | 2017 |
| Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide QL He, DV Titov, J Li, M Tan, Z Ye, Y Zhao, D Romo, JO Liu Angewandte Chemie International Edition 54 (6), 1859-1863, 2015 | 91 | 2015 |
| Identification and validation of protein targets of bioactive small molecules DV Titov, JO Liu Bioorganic & medicinal chemistry 20 (6), 1902-1909, 2012 | 57 | 2012 |
| Genetically encoded tools for measuring and manipulating metabolism M Choe, DV Titov Nature chemical biology 18 (5), 451-460, 2022 | 25 | 2022 |
| Listeria monocytogenes requires cellular respiration for NAD+ regeneration and pathogenesis R Rivera-Lugo, D Deng, A Anaya-Sanchez, S Tejedor-Sanz, E Tang, ... Elife 11, e75424, 2022 | 21 | 2022 |
| The Warburg Effect is the result of faster ATP production by glycolysis than respiration MA Kukurugya, S Rosset, DV Titov Proceedings of the National Academy of Sciences 121 (46), e2409509121, 2024 | 7 | 2024 |
| Regulator of Ras depalmitoylation and retrograde trafficking: a new hat for FKBP JO Liu, DV Titov, Y Dang, Q He Molecular cell 41 (2), 131-133, 2011 | 3 | 2011 |
| Genetically encoded tool for manipulation of ΔΨm identifies the latter as the driver of integrative stress response induced by ATP Synthase dysfunction M Choe, DV Titov bioRxiv, 2023 | 1 | 2023 |
| Mechanism of action of the antiproliferative natural product triptolide DV Titov The Johns Hopkins University, 2012 | 1 | 2012 |
| Protein prostheses for mitochondrial diseases or conditions V Mootha, D Titov, V Cracan, Z Grabarek US Patent App. 18/516,366, 2024 | | 2024 |
| Protein prostheses for mitochondrial diseases or conditions V Mootha, D Titov, V Cracan, Z Grabarek US Patent 11,866,736, 2024 | | 2024 |
| Data-driven model of glycolysis identifies the role of allostery in maintaining ATP homeostasis M Choe, T Einav, R Phillips, DV Titov bioRxiv, 2022.12. 28.522046, 2022 | | 2022 |
| Genetically Encoded Tools for Compartment-Specific Manipulation of NAD+/NADH or NADP+/NADPH Ratios V Cracan, D Titov, Z Grabarek, V Mootha Free Radical Biology and Medicine 100, S182, 2016 | | 2016 |
Vamsi MoothaMassachusetts General Hospital, Harvard Medical School, HHMIVerified email at hms.harvard.edu