Articles with public access mandates - John StreicherLearn more
Not available anywhere: 4
Synthesis and evaluation of a novel bivalent selective antagonist for the mu-delta opioid receptor heterodimer that reduces morphine withdrawal in mice
KM Olson, A Keresztes, JK Tashiro, LV Daconta, VJ Hruby, JM Streicher
Journal of medicinal chemistry 61 (14), 6075-6086, 2018
Mandates: US National Institutes of Health
Reversal of peripheral neuropathic pain by the small-molecule natural product physalin F via block of CaV2. 3 (R-type) and CaV2. 2 (N-type) voltage-gated calcium channels
Z Shan, S Cai, J Yu, Z Zhang, TGM Vallecillo, MJ Serafini, AM Thomas, ...
ACS chemical neuroscience 10 (6), 2939-2955, 2019
Mandates: US National Institutes of Health, National Natural Science Foundation of China
(−)-Hardwickiic acid and Hautriwaic acid induce Antinociception via blockade of Tetrodotoxin-sensitive voltage-dependent sodium channels
S Cai, SS Bellampalli, J Yu, W Li, Y Ji, EMK Wijeratne, A Dorame, S Luo, ...
ACS Chemical Neuroscience 10 (3), 1716-1728, 2018
Mandates: US National Institutes of Health, Children's Tumor Foundation, USA
Design of analgesic trivalent peptides with low withdrawal symptoms: Probing the antinociceptive profile of novel linear and cyclic peptides as opioid Pan ligands
A Stefanucci, P Minosi, S Pieretti, P Tanguturi, G Molnar, G Scioli, ...
ACS Chemical Neuroscience 14 (3), 506-515, 2023
Mandates: US National Institutes of Health, Government of Italy
Available somewhere: 52
Development of functionally selective, small molecule agonists at kappa opioid receptors
L Zhou, KM Lovell, KJ Frankowski, SR Slauson, AM Phillips, JM Streicher, ...
Journal of Biological Chemistry 288 (51), 36703-36716, 2013
Mandates: US National Institutes of Health
MAPK-activated protein kinase-2 in cardiac hypertrophy and cyclooxygenase-2 regulation in heart
JM Streicher, S Ren, H Herschman, Y Wang
Circulation research 106 (8), 1434-1443, 2010
Mandates: US National Institutes of Health
Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy
O Drews, O Tsukamoto, D Liem, J Streicher, Y Wang, P Ping
Circulation research 107 (9), 1094-1101, 2010
Mandates: US National Institutes of Health
Functional selectivity of 6′-guanidinonaltrindole (6′-GNTI) at κ-opioid receptors in striatal neurons
CL Schmid, JM Streicher, CE Groer, TA Munro, L Zhou, LM Bohn
Journal of Biological Chemistry 288 (31), 22387-22398, 2013
Mandates: US National Institutes of Health
Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention
JY Xie, M De Felice, CM Kopruszinski, N Eyde, J LaVigne, B Remeniuk, ...
Cephalalgia 37 (8), 780-794, 2017
Mandates: US National Institutes of Health
Analgesic potential of terpenes derived from Cannabis sativa
E Liktor-Busa, A Keresztes, J LaVigne, JM Streicher, TM Largent-Milnes
Pharmacological reviews 73 (4), 1269-1297, 2021
Mandates: US National Institutes of Health
Clozapine acts as an agonist at serotonin 2A receptors to counter MK-801-induced behaviors through a βarrestin2-independent activation of Akt
CL Schmid, JM Streicher, HY Meltzer, LM Bohn
Neuropsychopharmacology 39 (8), 1902-1913, 2014
Mandates: US National Institutes of Health, Howard Hughes Medical Institute
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury–associated peripheral sensory neuropathy via block of N-and T …
SS Bellampalli, Y Ji, A Moutal, S Cai, EMK Wijeratne, MA Gandini, J Yu, ...
Pain 160 (1), 117-135, 2019
Mandates: US Department of Defense, US National Institutes of Health, Canadian …
Discovery of small molecule kappa opioid receptor agonist and antagonist chemotypes through a HTS and hit refinement strategy
KJ Frankowski, MP Hedrick, P Gosalia, K Li, S Shi, D Whipple, P Ghosh, ...
ACS chemical neuroscience 3 (3), 221-236, 2012
Mandates: US National Institutes of Health
TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth
N Shah, S Kumar, N Zaman, CC Pan, JC Bloodworth, W Lei, JM Streicher, ...
Nature communications 9 (1), 1696, 2018
Mandates: US National Institutes of Health
Heat-shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK mitogen-activated protein kinase (MAPK) mechanism in mouse brain
W Lei, N Mullen, S McCarthy, C Brann, P Richard, J Cormier, K Edwards, ...
Journal of Biological Chemistry 292 (25), 10414-10428, 2017
Mandates: US National Institutes of Health
Strategies towards safer opioid analgesics—A review of old and upcoming targets
BR Varga, JM Streicher, S Majumdar
British journal of pharmacology 180 (7), 975-993, 2023
Mandates: US National Institutes of Health
A novel mu-delta opioid agonist demonstrates enhanced efficacy with reduced tolerance and dependence in mouse neuropathic pain models
W Lei, RH Vekariya, S Ananthan, JM Streicher
The journal of pain 21 (1-2), 146-160, 2020
Mandates: US National Institutes of Health
Targeting the CaVα–CaVβ interaction yields an antagonist of the N-type CaV2. 2 channel with broad antinociceptive efficacy
R Khanna, J Yu, X Yang, A Moutal, A Chefdeville, V Gokhale, Z Shuja, ...
Pain 160 (7), 1644-1661, 2019
Mandates: US Department of Defense, US National Institutes of Health, National Natural …
Analgesic properties of opioid/NK1 multitarget ligands with distinct in vitro profiles in naive and chronic constriction injury mice
J Starnowska, R Costante, K Guillemyn, K Popiolek-Barczyk, NN Chung, ...
ACS chemical neuroscience 8 (10), 2315-2324, 2017
Mandates: US National Institutes of Health, Research Foundation (Flanders), Canadian …
The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers …
GW Stevenson, A Luginbuhl, C Dunbar, J LaVigne, J Dutra, P Atherton, ...
Pharmacology Biochemistry and Behavior 132, 49-55, 2015
Mandates: US National Institutes of Health
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