Mesenchymal stem cells and insulin‐like growth factor‐I gene‐enhanced mesenchymal stem cells improve structural aspects of healing in equine flexor digitorum superficialis tendons LV Schnabel, ME Lynch, MCH van der Meulen, AE Yeager, ... Journal of Orthopaedic Research 27 (10), 1392-1398, 2009 | 338 | 2009 |
Engineered culture models for studies of tumor-microenvironment interactions DW Infanger, ME Lynch, C Fischbach Annual review of biomedical engineering 15 (1), 29-53, 2013 | 160 | 2013 |
Tibial compression is anabolic in the adult mouse skeleton despite reduced responsiveness with aging ME Lynch, RP Main, Q Xu, TL Schmicker, MB Schaffler, TM Wright, ... Bone 49 (3), 439-446, 2011 | 145 | 2011 |
In vivo tibial compression decreases osteolysis and tumor formation in a human metastatic breast cancer model ME Lynch, D Brooks, S Mohanan, MJ Lee, P Polamraju, K Dent, ... Journal of Bone and Mineral Research 28 (11), 2357-2367, 2013 | 125 | 2013 |
Cancellous bone adaptation to tibial compression is not sex dependent in growing mice ME Lynch, RP Main, Q Xu, DJ Walsh, MB Schaffler, TM Wright, ... Journal of applied physiology 109 (3), 685-691, 2010 | 123 | 2010 |
In vivo tibial stiffness is maintained by whole bone morphology and cross-sectional geometry in growing female mice RP Main, ME Lynch, MCH van der Meulen Journal of biomechanics 43 (14), 2689-2694, 2010 | 80 | 2010 |
Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis F He, AE Chiou, HC Loh, M Lynch, BR Seo, YH Song, MJ Lee, R Hoerth, ... Proceedings of the National Academy of Sciences 114 (40), 10542-10547, 2017 | 75 | 2017 |
Load-induced changes in bone stiffness and cancellous and cortical bone mass following tibial compression diminish with age in female mice RP Main, ME Lynch, MCH van der Meulen Journal of Experimental Biology 217 (10), 1775-1783, 2014 | 71 | 2014 |
The predictive link between matrix and metastasis LE Barney, LE Jansen, SR Polio, S Galarza, ME Lynch, SR Peyton Current opinion in chemical engineering 11, 85-93, 2016 | 54 | 2016 |
Biomechanical forces in the skeleton and their relevance to bone metastasis: biology and engineering considerations ME Lynch, C Fischbach Advanced drug delivery reviews 79, 119-134, 2014 | 45 | 2014 |
Three-dimensional mechanical loading modulates the osteogenic response of mesenchymal stem cells to tumor-derived soluble signals ME Lynch, AE Chiou, MJ Lee, SC Marcott, PV Polamraju, Y Lee, ... Tissue Engineering Part A 22 (15-16), 1006-1015, 2016 | 40 | 2016 |
Mechanically-loaded breast cancer cells modify osteocyte mechanosensitivity by secreting factors that increase osteocyte dendrite formation and downstream resorption W Wang, BA Sarazin, G Kornilowicz, ME Lynch Frontiers in Endocrinology 9, 352, 2018 | 27 | 2018 |
Mechanical loading prevents bone destruction and exerts anti-tumor effects in the MOPC315. BM. Luc model of myeloma bone disease M Rummler, F Ziouti, AL Bouchard, A Brandl, GN Duda, B Bogen, ... Acta Biomaterialia 119, 247-258, 2021 | 23 | 2021 |
Microgravity-induced alterations of mouse bones are compartment-and site-specific and vary with age JC Coulombe, BA Sarazin, Z Mullen, AM Ortega, EW Livingston, ... Bone 151, 116021, 2021 | 19 | 2021 |
Perfusion applied to a 3D model of bone metastasis results in uniformly dispersed mechanical stimuli B Liu, S Han, BP Hedrick, Y Modarres‐Sadeghi, ME Lynch Biotechnology and Bioengineering 115 (4), 1076-1085, 2018 | 19 | 2018 |
Mechanobiology of bone metastatic cancer BA Sarazin, CL Ihle, P Owens, ME Lynch Current osteoporosis reports, 1-12, 2021 | 10 | 2021 |
Multiphysics simulation of a compression–perfusion combined bioreactor to predict the mechanical microenvironment during bone metastatic breast cancer loading experiments B Liu, S Han, Y Modarres‐Sadeghi, ME Lynch Biotechnology and Bioengineering 118 (5), 1779-1792, 2021 | 9 | 2021 |
The role of mechanobiology in cancer metastasis ME Lynch, CP Neu, B Seelbinder, KP McCreery Mechanobiology, 65-78, 2020 | 8 | 2020 |
Reduced local mechanical stimuli in spaceflight diminishes osteocyte lacunar morphometry and spatial heterogeneity in mouse cortical bone JC Coulombe, ZA Mullen, AM Weins, LE Fisher, ME Lynch, LS Stodieck, ... bioRxiv, 2022.01. 04.474962, 2022 | 4 | 2022 |
Application of machine learning classifiers for microcomputed tomography data assessment of mouse bone microarchitecture JC Coulombe, ZK Mullen, ME Lynch, LS Stodieck, VL Ferguson MethodsX 8, 101497, 2021 | 4 | 2021 |