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Neil C. Sheppard
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Nanomaterials for T-cell cancer immunotherapy
N Gong, NC Sheppard, MM Billingsley, CH June, MJ Mitchell
Nature Nanotechnology 16 (1), 25-36, 2021
2342021
Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens
F Wegmann, KH Gartlan, AM Harandi, SA Brinckmann, M Coccia, ...
Nature biotechnology 30 (9), 883-888, 2012
2272012
Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity
L Kong, NC Sheppard, GBE Stewart-Jones, CL Robson, H Chen, X Xu, ...
Journal of molecular biology 403 (1), 131-147, 2010
1222010
Genetic engineering of T cells for immunotherapy
GI Ellis, NC Sheppard, JL Riley
Nature Reviews Genetics 22 (7), 427-447, 2021
1082021
Orthogonal design of experiments for optimization of lipid nanoparticles for mRNA engineering of CAR T cells
MM Billingsley, AG Hamilton, D Mai, SK Patel, KL Swingle, NC Sheppard, ...
Nano letters 22 (1), 533-542, 2021
1062021
HERV-K–specific T cells eliminate diverse HIV-1/2 and SIV primary isolates
RB Jones, KE Garrison, S Mujib, V Mihajlovic, N Aidarus, DV Hunter, ...
The Journal of clinical investigation 122 (12), 2012
1042012
EV01: a phase I trial in healthy HIV negative volunteers to evaluate a clade C HIV vaccine, NYVAC-C undertaken by the EuroVacc Consortium
PA Bart, R Goodall, T Barber, A Harari, A Guimaraes-Walker, M Khonkarly, ...
Vaccine 26 (25), 3153-3161, 2008
782008
Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens
NC Sheppard, SA Brinckmann, KH Gartlan, M Puthia, C Svanborg, ...
International immunology 26 (10), 531-538, 2014
752014
Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates
BE Verstrepen, AD Bins, CS Rollier, P Mooij, G Koopman, NC Sheppard, ...
Vaccine 26 (26), 3346-3351, 2008
732008
The TRIM5α genotype of rhesus macaques affects acquisition of simian immunodeficiency virus SIVsmE660 infection after repeated limiting-dose intrarectal challenge
MR Reynolds, JB Sacha, AM Weiler, GJ Borchardt, CE Glidden, ...
Journal of virology 85 (18), 9637-9640, 2011
682011
Vaccination with cancer-and HIV infection-associated endogenous retrotransposable elements is safe and immunogenic
JB Sacha, IJ Kim, L Chen, JH Ullah, DA Goodwin, HA Simmons, ...
The Journal of Immunology 189 (3), 1467-1479, 2012
622012
Comparison of human and rhesus macaque T-cell responses elicited by boosting with NYVAC encoding human immunodeficiency virus type 1 clade C immunogens
P Mooij, SS Balla-Jhagjhoorsingh, N Beenhakker, P van Haaften, I Baak, ...
Journal of virology 83 (11), 5881-5889, 2009
412009
Ionizable lipid nanoparticles with integrated immune checkpoint inhibition for mRNA CAR T cell engineering
AG Hamilton, KL Swingle, RA Joseph, D Mai, N Gong, MM Billingsley, ...
Advanced Healthcare Materials 12 (30), 2301515, 2023
372023
Combined disruption of T cell inflammatory regulators Regnase-1 and Roquin-1 enhances antitumor activity of engineered human T cells
D Mai, O Johnson, J Reff, TJ Fan, J Scholler, NC Sheppard, CH June
Proceedings of the National Academy of Sciences 120 (12), e2218632120, 2023
372023
Responsive biomaterials: optimizing control of cancer immunotherapy
L Xue, AS Thatte, D Mai, RM Haley, N Gong, X Han, K Wang, ...
Nature Reviews Materials 9 (2), 100-118, 2024
332024
Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells
AR Haas, RJ Golden, LA Litzky, B Engels, L Zhao, F Xu, JA Taraszka, ...
Molecular Therapy 31 (8), 2309-2325, 2023
282023
Antigen presenting cell mimetic lipid nanoparticles for rapid mRNA CAR T cell cancer immunotherapy
AE Metzloff, MS Padilla, N Gong, MM Billingsley, X Han, M Merolle, D Mai, ...
Advanced Materials, 2313226, 2024
222024
Tumor-derived small extracellular vesicles inhibit the efficacy of CAR T cells against solid tumors
W Zhong, Z Xiao, Z Qin, J Yang, Y Wen, Z Yu, Y Li, NC Sheppard, ...
Cancer research 83 (16), 2790-2806, 2023
182023
Human endogenous retrovirus K (HML-2) Gag-and Env-specific T-cell responses are infrequently detected in HIV-1-infected subjects using standard peptide matrix-based screening
RB Jones, VM John, DV Hunter, E Martin, S Mujib, V Mihajlovic, ...
Clinical and Vaccine Immunology 19 (2), 288-292, 2012
152012
Adjuvant
Q Sattentau, N Sheppard
US Patent App. 12/293,380, 2009
152009
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