Targeting KRAS mutant cancers with a covalent G12C-specific inhibitor MR Janes, J Zhang, LS Li, R Hansen, U Peters, X Guo, Y Chen, A Babbar, ... Cell 172 (3), 578-589. e17, 2018 | 1118 | 2018 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. M Chen, A Suzuki, S Thakkar, K Yu, C Hu, W Tong Drug Discov Today 21 (4), 648-653, 2016 | 375 | 2016 |
Safety and pharmacokinetics of novel selective vascular endothelial growth factor receptor-2 inhibitor YN968D1 in patients with advanced malignancies J Li, X Zhao, L Chen, H Guo, F Lv, K Jia, K Yv, F Wang, C Li, J Qian, ... BMC cancer 10, 1-8, 2010 | 320 | 2010 |
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia S Klossowski, H Miao, K Kempinska, T Wu, T Purohit, EG Kim, ... The Journal of clinical investigation 130 (2), 981-997, 2020 | 205 | 2020 |
Absorption, disposition, and pharmacokinetics of saponins from Chinese medicinal herbs: what do we know and what do we need to know more? K Yu, F Chen, C Li Current drug metabolism 13 (5), 577-598, 2012 | 178 | 2012 |
High daily dose and being a substrate of cytochrome P450 enzymes are two important predictors of drug-induced liver injury K Yu, X Geng, M Chen, J Zhang, B Wang, K Ilic, W Tong Drug metabolism and disposition 42 (4), 744-750, 2014 | 134 | 2014 |
A metabonomic investigation on the biochemical perturbation in liver failure patients caused by hepatitis B virus K Yu, G Sheng, J Sheng, Y Chen, W Xu, X Liu, H Cao, H Qu, Y Cheng, ... Journal of proteome research 6 (7), 2413-2419, 2007 | 117 | 2007 |
Quantitative analysis and chromatographic fingerprinting for the quality evaluation of Scutellaria baicalensis Georgi using capillary electrophoresis K Yu, Y Gong, Z Lin, Y Cheng Journal of Pharmaceutical and Biomedical Analysis 43 (2), 540-548, 2007 | 98 | 2007 |
Discriminating the genuineness of Chinese medicines using least squares support vector machines K Yu, Y Cheng Chinese Journal of Analytical Chemistry 34 (4), 561-564, 2006 | 60 | 2006 |
Simultaneous determination of eight active components in Chinese medicine ‘YIQING’capsule using high-performance liquid chromatography H Qu, Y Ma, K Yu, Y Cheng Journal of pharmaceutical and biomedical analysis 43 (1), 66-72, 2007 | 55 | 2007 |
Simultaneously determination of five ginsenosides in rabbit plasma using solid-phase extraction and HPLC/MS technique after intravenous administration of ‘SHENMAI’injection K Yu, Y Ma, Q Shao, H Qu, Y Cheng Journal of pharmaceutical and biomedical analysis 44 (2), 532-539, 2007 | 41 | 2007 |
Determination of paeonol and paeoniflorin in Chinese medicine Cortex Moutan and ‘Shuangdan’granule by micellar electrokinetic capillary chromatography K Yu, YW Wang, YY Cheng Journal of pharmaceutical and biomedical analysis 40 (5), 1257-1262, 2006 | 33 | 2006 |
Gas chromatography-mass spectrometry based on metabonomics study of carbon tetrachloride-induced acute liver injury in mice H Xin, G Yi-Fei, Y Ke, C Yi-Yu Chinese Journal of Analytical Chemistry 35 (12), 1736-1740, 2007 | 30 | 2007 |
Machine learning techniques for the prediction of the peptide mobility in capillary zone electrophoresis K Yu, Y Cheng Talanta 71 (2), 676-682, 2007 | 27 | 2007 |
Development of an HPLC–UV–ELSD Method for Quantification of Multiple Components of a Chinese Medicine Made from Radix salvia miltiorrhiza and Panax notoginseng Y Lu, K Yu, HB Qu, YY Cheng Chromatographia 65, 19-24, 2007 | 24 | 2007 |
Strategies for improving the quantitative bioanalytical performance of LC-MS in pharmacokinetic studies L Li, D Tian, F Chen, J Yang, K Yu, Y Sun Current drug metabolism 13 (9), 1206-1212, 2012 | 23 | 2012 |
Metabonomic analysis of hepatitis B virus-induced liver failure: identification of potential diagnostic biomarkers by fuzzy support vector machine Y Mao, X Huang, K Yu, H Qu, C Liu, Y Cheng Journal of Zhejiang University SCIENCE B 9 (6), 474-481, 2008 | 22 | 2008 |
Optimization of the buffer system of micellar electrokinetic capillary chromatography for the separation of the active components in Chinese medicine ‘SHUANGDAN’granule by … K Yu, Z Lin, Y Cheng Analytica chimica acta 562 (1), 66-72, 2006 | 22 | 2006 |
Pharmacokinetics and disposition of circulating iridoids and organic acids in rats intravenously receiving ReDuNing injection C Cheng, F Du, K Yu, F Xu, F Wang, L Li, OE Olaleye, J Yang, F Chen, ... Drug Metabolism and Disposition 44 (11), 1853-1858, 2016 | 21 | 2016 |
Determination of the active components in chinese herb cortex moutan by MEKC and LC K Yu, YW Wang, YY Cheng Chromatographia 63, 359-364, 2006 | 21 | 2006 |