| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13929* | 2021 |
| SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism M Maceyka, H Sankala, NC Hait, H Le Stunff, H Liu, R Toman, C Collier, ... Journal of Biological Chemistry 280 (44), 37118-37129, 2005 | 769 | 2005 |
| Sphingolipid signalling in Arabidopsis guard cells involves heterotrimeric G proteins S Coursol, LM Fan, HL Stunff, S Spiegel, S Gilroy, SM Assmann Nature 423 (6940), 651-654, 2003 | 421 | 2003 |
| Generation and metabolism of bioactive sphingosine‐1‐phosphate HL Stunff, S Milstien, S Spiegel Journal of cellular biochemistry 92 (5), 882-899, 2004 | 229 | 2004 |
| Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis H Le Stunff, I Galve-Roperh, C Peterson, S Milstien, S Spiegel The Journal of cell biology 158 (6), 1039-1049, 2002 | 218 | 2002 |
| Plasma dihydroceramides are diabetes susceptibility biomarker candidates in mice and humans L Wigger, C Cruciani-Guglielmacci, A Nicolas, J Denom, N Fernandez, ... Cell reports 18 (9), 2269-2279, 2017 | 212 | 2017 |
| Role of sphingosine kinase 2 in cell migration toward epidermal growth factor NC Hait, S Sarkar, H Le Stunff, A Mikami, M Maceyka, S Milstien, ... Journal of Biological Chemistry 280 (33), 29462-29469, 2005 | 203 | 2005 |
| The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning D Escalante-Alcalde, L Hernandez, H Le Stunff, R Maeda, HS Lee, ... Oxford University Press for The Company of Biologists Limited 130 (19), 4623 …, 2003 | 193 | 2003 |
| Arabidopsis sphingosine kinase and the effects of phytosphingosine-1-phosphate on stomatal aperture S Coursol, H Le Stunff, DV Lynch, S Gilroy, SM Assmann, S Spiegel Plant Physiology 137 (2), 724-737, 2005 | 177 | 2005 |
| Recycling of sphingosine is regulated by the concerted actions of sphingosine-1-phosphate phosphohydrolase 1 and sphingosine kinase 2 H Le Stunff, P Giussani, M Maceyka, S Lépine, S Milstien, S Spiegel Journal of Biological Chemistry 282 (47), 34372-34380, 2007 | 140 | 2007 |
| Sphingosine-1-phosphate and lipid phosphohydrolases H Le Stunff, C Peterson, H Liu, S Milstien, S Spiegel Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2002 | 136 | 2002 |
| The GK rat: a prototype for the study of non-overweight type 2 diabetes B Portha, MH Giroix, C Tourrel-Cuzin, H Le-Stunff, J Movassat animal models in diabetes research, 125-159, 2012 | 129 | 2012 |
| Ceramide synthase 4 and de novo production of ceramides with specific N-acyl chain lengths are involved in glucolipotoxicity-induced apoptosis of INS-1 β-cells J Véret, N Coant, EV Berdyshev, A Skobeleva, N Therville, D Bailbé, ... Biochemical Journal 438 (1), 177-189, 2011 | 121 | 2011 |
| The Pro-451 to Leu polymorphism within the C-terminal tail of P2X7 receptor impairs cell death but not phospholipase D activation in murine thymocytes H Le Stunff, R Auger, J Kanellopoulos, MN Raymond Journal of Biological Chemistry 279 (17), 16918-16926, 2004 | 113 | 2004 |
| Characterization of murine sphingosine-1-phosphate phosphohydrolase H Le Stunff, C Peterson, R Thornton, S Milstien, SM Mandala, S Spiegel Journal of Biological Chemistry 277 (11), 8920-8927, 2002 | 113 | 2002 |
| Sphingolipid metabolism: new insight into ceramide-induced lipotoxicity in muscle cells CL Bandet, S Tan-Chen, O Bourron, H Le Stunff, E Hajduch International journal of molecular sciences 20 (3), 479, 2019 | 102 | 2019 |
| Estradiol regulates energy balance by ameliorating hypothalamic ceramide-induced ER stress I González-García, C Contreras, Á Estévez-Salguero, F Ruíz-Pino, ... Cell Reports 25 (2), 413-423. e5, 2018 | 82 | 2018 |
| Role of sphingosine-1-phosphate phosphatase 1 in epidermal growth factor-induced chemotaxis H Le Stunff, A Mikami, P Giussani, JP Hobson, PS Jolly, S Milstien, ... Journal of Biological Chemistry 279 (33), 34290-34297, 2004 | 65 | 2004 |
| Inhibition of central de novo ceramide synthesis restores insulin signaling in hypothalamus and enhances β-cell function of obese Zucker rats M Campana, L Bellini, C Rouch, L Rachdi, N Coant, N Butin, CL Bandet, ... Molecular metabolism 8, 23-36, 2018 | 64 | 2018 |
| Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide P Giussani, M Maceyka, H Le Stunff, A Mikami, S Lépine, E Wang, S Kelly, ... Molecular and cellular biology 26 (13), 5055-5069, 2006 | 64 | 2006 |
Sarah SpiegelProfessor of Biochemistry and Molecular Biology, VCUVerified email at vcuhealth.org
