Stabilization of the Max homodimer with a small molecule attenuates Myc-driven transcription NB Struntz, A Chen, A Deutzmann, RM Wilson, E Stefan, HL Evans, ... Cell chemical biology 26 (5), 711-723. e14, 2019 | 128 | 2019 |
Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma E Poon, T Liang, Y Jamin, S Walz, C Kwok, A Hakkert, K Barker, Z Urban, ... The Journal of clinical investigation 130 (11), 5875-5892, 2020 | 55 | 2020 |
Stabilization of ATF5 by TAK1–nemo-like kinase critically regulates the interleukin-1β-stimulated C/EBP signaling pathway ZY Zhang, SZ Li, HH Zhang, QR Wu, J Gong, T Liang, L Gao, NN Xing, ... Molecular and cellular biology 35 (5), 778-788, 2015 | 25 | 2015 |
CDK9 inhibition is selective for transcriptionally addicted tumors harboring MYC genomic amplifications MA Day, ND Obholzer, A Pandey, T Chen, T Liang, RA Villagomez, ... Cancer Research 81 (13_Supplement), 1141-1141, 2021 | 2 | 2021 |
Multistage regulator based on tandem promoters and CRISPR/Cas H Jia, T Liang, Z Wang, Z He, Y Liu, L Yang, Y Zeng, S Liu, L Tang, ... ACS synthetic biology 3 (12), 1007-1010, 2014 | 2 | 2014 |
Abstract A066 Acquired resistance to temozolomide in the Th-MYCN mouse as a clinically-relevant platform to evaluate novel therapeutic strategies against high … E Poon, T Liang, G Barone, BM Costa, S Heuss, SP Robinson, C Lin, ... Cancer Research 84 (17_Supplement), A066-A066, 2024 | | 2024 |
Acquired resistance to temozolomide in the Th-MYCN mouse as a clinically-relevant platform to evaluate novel therapeutic strategies against high-risk neuroblastoma E Poon, T Liang, G Barone, BM Costa, S Heuss, SP Robinson, C Lin, ... CANCER RESEARCH 84 (17), 2024 | | 2024 |
Small molecule microarray lysate screen identifies bromodomain ligands that target the MYC transcription regulatory network EB Cohen, Z Ma, WL Glore, OA Volkov, T Liang, ND Obholzer, AC Clay, ... MOLECULAR CANCER THERAPEUTICS 22 (12), 2023 | | 2023 |
Abstract A059: Small molecule microarray lysate screen identifies bromodomain ligands that target the MYC transcription regulatory network EB Cohen, Z Ma, WL Glore, OA Volkov, T Liang, ND Obholzer, AC Clay, ... Molecular Cancer Therapeutics 22 (12_Supplement), A059-A059, 2023 | | 2023 |