Thiazole–aminopiperidine hybrid analogues: Design and synthesis of novel Mycobacterium tuberculosis GyrB inhibitors VU Jeankumar, J Renuka, P Santosh, V Soni, JP Sridevi, P Suryadevara, ... European journal of medicinal chemistry 70, 143-153, 2013 | 86 | 2013 |
Ligand-controlled regioselective copper-catalyzed trifluoromethylation to generate (trifluoromethyl) allenes BR Ambler, S Peddi, RA Altman Organic letters 17 (10), 2506-2509, 2015 | 51 | 2015 |
Identification and structure–activity relationship study of carvacrol derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors R Alokam, VU Jeankumar, JP Sridevi, SS Matikonda, S Peddi, M Alvala, ... Journal of Enzyme Inhibition and Medicinal Chemistry 29 (4), 547-554, 2014 | 47 | 2014 |
Bifunctional elastin-like polypeptide nanoparticles bind rapamycin and integrins and suppress tumor growth in vivo JP Dhandhukia, P Shi, S Peddi, Z Li, S Aluri, Y Ju, D Brill, W Wang, ... Bioconjugate chemistry 28 (11), 2715-2728, 2017 | 39 | 2017 |
Discovery and Structure Optimization of a Series of Isatin Derivatives as Mycobacterium tuberculosis Chorismate Mutase Inhibitors VU Jeankumar, R Alokam, JP Sridevi, P Suryadevara, SS Matikonda, ... Chemical biology & drug design 83 (4), 498-506, 2014 | 39 | 2014 |
Copper-catalyzed radical bis (trifluoromethylation) of alkynes and 1, 3-enynes H Shen, H Xiao, L Zhu, C Li Synlett 31 (01), 41-44, 2020 | 33 | 2020 |
Nanotoxicology of an elastin-like polypeptide rapamycin formulation for breast cancer S Peddi, SK Roberts, JA MacKay Biomacromolecules 21 (3), 1091-1102, 2020 | 24 | 2020 |
Berunda polypeptides: multi-headed fusion proteins promote subcutaneous administration of rapamycin to breast cancer in vivo JP Dhandhukia, Z Li, S Peddi, S Kakan, A Mehta, D Tyrpak, J Despanie, ... Theranostics 7 (16), 3856, 2017 | 20 | 2017 |
The humanin peptide mediates ELP nanoassembly and protects human retinal pigment epithelial cells from oxidative stress Z Li, PG Sreekumar, S Peddi, DR Hinton, R Kannan, JA MacKay Nanomedicine: Nanotechnology, Biology and Medicine 24, 102111, 2020 | 18 | 2020 |
Intracellular delivery of Rapamycin from FKBP elastin-like polypeptides is consistent with macropinocytosis S Peddi, X Pan, JA MacKay Frontiers in pharmacology 9, 1184, 2018 | 18 | 2018 |
Berunda polypeptides: biheaded rapamycin carriers for subcutaneous treatment of autoimmune dry eye disease C Lee, H Guo, W Klinngam, SR Janga, F Yarber, S Peddi, MC Edman, ... Molecular pharmaceutics 16 (7), 3024-3039, 2019 | 16 | 2019 |
Copper-catalyzed decarboxylative trifluoromethylation of propargyl bromodifluoroacetates BR Ambler, S Peddi, RA Altman Synthesis 46 (14), 1938-1946, 2014 | 15 | 2014 |
Adaptable antibody Nanoworms designed for non-Hodgkin lymphoma C Lee, S Peddi, C Anderson, H Su, H Cui, AL Epstein, JA MacKay Biomaterials 262, 120338, 2020 | 12 | 2020 |
Molecular targeting of immunosuppressants using a bifunctional elastin-like polypeptide Y Ju, H Guo, F Yarber, MC Edman, S Peddi, SR Janga, JA MacKay, ... Bioconjugate chemistry 30 (9), 2358-2372, 2019 | 11 | 2019 |
Intralacrimal Sustained Delivery of Rapamycin Shows Therapeutic Effects without Systemic Toxicity in a Mouse Model of Autoimmune Dacryoadenitis Characteristic of Sjogren’s Syndrome Y Ju, MC Edman, H Guo, SR Janga, S Peddi, SG Louie, JA Junge, ... Biomacromolecules 22 (3), 1102-1114, 2020 | 8 | 2020 |
Hydra-Elastin-like polypeptides increase rapamycin potency when targeting cell surface GRP78 H Avila, J Yu, G Boddu, A Phan, A Truong, S Peddi, H Guo, SJ Lee, ... Biomacromolecules 23 (8), 3116-3129, 2022 | 5 | 2022 |
Multimeric elastin-like polypeptides JA MacKay, M Shah, SF Hamm-Alvarez, H Guo, S Peddi US Patent 11,464,867, 2022 | 4 | 2022 |
Berunda Polypeptides Carrying Rapalogues Inhibit Tumor mTORC1 Better than Oral Everolimus S Peddi, JA MacKay Biomacromolecules 21 (8), 3038-3046, 2020 | 3 | 2020 |
Protein polymer fusions for subcutaneous delivery of small molecules JA MacKay, JP Dhandhukia, S Peddi, SK Roberts US Patent App. 16/306,825, 2019 | 2 | 2019 |
Multimeric elastin-like polypeptides JA MacKay, M Shah, SF Hamm-Alvarez, H Guo, S Peddi US Patent App. 17/963,037, 2023 | | 2023 |