AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice YU Li, S Xu, MM Mihaylova, B Zheng, X Hou, B Jiang, O Park, Z Luo, ... Cell metabolism 13 (4), 376-388, 2011 | 1819 | 2011 |
A dimeric 14-3-3 protein is an essential cofactor for Raf kinase activity G Tzivion, Z Luo, J Avruch Nature 394 (6688), 88-92, 1998 | 646 | 1998 |
Ras activation of the Raf kinase: tyrosine kinase recruitment of the MAP kinase cascade. J Avruch, A Khokhlatchev, JM Kyriakis, Z Luo, G Tzivion, D Vavvas, ... Recent progress in hormone research 56, 127-155, 2001 | 618 | 2001 |
AMPK, the metabolic syndrome and cancer Z Luo, AK Saha, X Xiang, NB Ruderman Trends in pharmacological sciences 26 (2), 69-76, 2005 | 503 | 2005 |
Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription LFF Chen Y, Zhou K, Wang R, Liu Y, Kwak YD, Ma T, Thompson RC, Zhao Y, Smith ... Proc Natl Acad Sci U S A 106 (10), 3907-12, 2008 | 481* | 2008 |
AMPK as a metabolic tumor suppressor: control of metabolism and cell growth Z Luo, M Zang, W Guo Future oncology 6 (3), 457-470, 2010 | 467 | 2010 |
AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise M Kelly, C Keller, PR Avilucea, P Keller, Z Luo, X Xiang, M Giralt, ... Biochemical and biophysical research communications 320 (2), 449-454, 2004 | 365 | 2004 |
Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver Y Li, S Xu, A Giles, K Nakamura, JW Lee, X Hou, G Donmez, J Li, Z Luo, ... The FASEB Journal 25 (5), 1664, 2011 | 347 | 2011 |
Oligomerization activates c-Raf-1 through a Ras-dependent mechanism Z Luo, G Tzivion, PJ Belshaw, D Vavvas, M Marshall, J Avruch Nature 383 (6596), 181-185, 1996 | 337 | 1996 |
AMP-activated protein kinase activators can inhibit the growth of prostate cancer cells by multiple mechanisms X Xiang, AK Saha, R Wen, NB Ruderman, Z Luo Biochemical and biophysical research communications 321 (1), 161-167, 2004 | 316 | 2004 |
Palmitate modulates intracellular signaling, induces endoplasmic reticulum stress, and causes apoptosis in mouse 3T3-L1 and rat primary preadipocytes W Guo, S Wong, W Xie, T Lei, Z Luo American journal of physiology-endocrinology and metabolism 293 (2), E576-E586, 2007 | 308 | 2007 |
Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1 ZG Luo, Q Wang, JZ Zhou, J Wang, Z Luo, M Liu, X He, A Wynshaw-Boris, ... Neuron 35 (3), 489-505, 2002 | 286 | 2002 |
Interleukin-6 regulation of AMP-activated protein kinase: potential role in the systemic response to exercise and prevention of the metabolic syndrome NB Ruderman, C Keller, AM Richard, AK Saha, Z Luo, X Xiang, M Giralt, ... Diabetes 55 (Supplement_2), S48-S54, 2006 | 236 | 2006 |
Actin-biding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-α activation of SAPK in melanoma cells A Marti, Z Luo, C Cunningham, Y Ohta, J Hartwig, TP Stossel, JM Kyriakis, ... Journal of Biological Chemistry 272 (5), 2620-2628, 1997 | 222 | 1997 |
Hyperglycemia and insulin resistance: possible mechanisms E Tomás, YENS LIN, Z Dagher, A Saha, Z Luo, Y Ido, NB Ruderman Annals of the New York Academy of Sciences 967 (1), 43-51, 2002 | 210 | 2002 |
Calyculin A-induced vimentin phosphorylation sequesters 14-3-3 and displaces other 14-3-3 partners in vivo G Tzivion, ZJ Luo, J Avruch Journal of Biological Chemistry 275 (38), 29772-29778, 2000 | 209 | 2000 |
SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL P Chakrabarti, T English, S Karki, L Qiang, R Tao, J Kim, Z Luo, ... Journal of lipid research 52 (9), 1693-1701, 2011 | 203 | 2011 |
An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ Z Luo, B Diaz, MS Marshall, J Avruch Molecular and cellular biology, 1997 | 167 | 1997 |
Erbin suppresses the MAP kinase pathway YZ Huang, M Zang, WC Xiong, Z Luo, L Mei Journal of Biological Chemistry 278 (2), 1108-1114, 2003 | 156 | 2003 |
Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1 M Zang, C Hayne, Z Luo Journal of Biological Chemistry 277 (6), 4395-4405, 2002 | 148 | 2002 |