The genotype-tissue expression (GTEx) project J Lonsdale, J Thomas, M Salvatore, R Phillips, E Lo, S Shad, R Hasz, ... Nature genetics 45 (6), 580-585, 2013 | 8150 | 2013 |
The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans GTEx Consortium, KG Ardlie, DS Deluca, AV Segrè, TJ Sullivan, ... Science 348 (6235), 648-660, 2015 | 4775 | 2015 |
Carcinogenicity of tetrachlorvinphos, parathion, malathion, diazinon, and glyphosate KZ Guyton, D Loomis, Y Grosse, F El Ghissassi, L Benbrahim-Tallaa, ... The Lancet Oncology 16 (5), 490-491, 2015 | 1110 | 2015 |
Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis MT Smith, KZ Guyton, CF Gibbons, JM Fritz, CJ Portier, I Rusyn, ... Environmental health perspectives 124 (6), 713-721, 2016 | 623 | 2016 |
NADPH oxidase–derived free radicals are key oxidants in alcohol-induced liver disease H Kono, I Rusyn, M Yin, E Gäbele, S Yamashina, A Dikalova, MB Kadiiska, ... The Journal of clinical investigation 106 (7), 867-872, 2000 | 617 | 2000 |
Standardizing global gene expression analysis between laboratories and across platforms Toxicogenomics Research Consortium Weis BK weis@ niehs. nih. gov 1 b Nature methods 2 (5), 351-356, 2005 | 608 | 2005 |
In vitro models for liver toxicity testing VY Soldatow, EL LeCluyse, LG Griffith, I Rusyn Toxicology research 2 (1), 23-39, 2013 | 574 | 2013 |
Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis RA Roberts, PE Ganey, C Ju, LM Kamendulis, I Rusyn, JE Klaunig Toxicological Sciences 96 (1), 2-15, 2007 | 464 | 2007 |
Effect of predicted protein-truncating genetic variants on the human transcriptome MA Rivas, M Pirinen, DF Conrad, M Lek, EK Tsang, KJ Karczewski, ... Science 348 (6235), 666-669, 2015 | 362 | 2015 |
The role of Kupffer cell oxidant production in early ethanol-induced liver disease MD Wheeler, H Kono, M Yin, M Nakagami, T Uesugi, GE Arteel, E Gäbele, ... Free Radical Biology and Medicine 31 (12), 1544-1549, 2001 | 330 | 2001 |
Modes of action and species-specific effects of di-(2-ethylhexyl) phthalate in the liver I Rusyn, JM Peters, ML Cunningham Critical reviews in toxicology 36 (5), 459-479, 2006 | 307 | 2006 |
Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development U Marx, T Akabane, TB Andersson, E Baker, M Beilmann, S Beken, ... Altex 37 (3), 365, 2020 | 254 | 2020 |
Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA) CJ Portier, BK Armstrong, BC Baguley, X Baur, I Belyaev, R Bellé, ... J Epidemiol Community Health 70 (8), 741-745, 2016 | 240 | 2016 |
Predicting drug-induced hepatotoxicity using QSAR and toxicogenomics approaches Y Low, T Uehara, Y Minowa, H Yamada, Y Ohno, T Urushidani, A Sedykh, ... Chemical research in toxicology 24 (8), 1251-1262, 2011 | 235 | 2011 |
Glycine: a new anti-inflammatory immunonutrient MD Wheeler, K Ikejema, N Enomoto, RF Stacklewitz, V Seabra, Z Zhong, ... Cellular and Molecular Life Sciences CMLS 56, 843-856, 1999 | 233 | 1999 |
Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis … IP Pogribny, A Starlard-Davenport, VP Tryndyak, T Han, SA Ross, I Rusyn, ... Laboratory investigation 90 (10), 1437-1446, 2010 | 224 | 2010 |
DNA damage by peroxynitrite characterized with DNA repair enzymes B Epe, D Ballmaier, I Roussyn, K Briviba, H Sies Nucleic acids research 24 (21), 4105-4110, 1996 | 221 | 1996 |
Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet IP Pogribny, VP Tryndyak, TV Bagnyukova, S Melnyk, B Montgomery, ... Journal of hepatology 51 (1), 176-186, 2009 | 219 | 2009 |
Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases J Yang, T Huang, F Petralia, Q Long, B Zhang, C Argmann, Y Zhao, ... Scientific reports 5 (1), 1-16, 2015 | 215 | 2015 |
Role of epigenetic aberrations in the development and progression of human hepatocellular carcinoma IP Pogribny, I Rusyn Cancer letters 342 (2), 223-230, 2014 | 211 | 2014 |