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| Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis D Anastasiou, Y Yu, WJ Israelsen, JK Jiang, MB Boxer, BS Hong, ... Nature chemical biology 8 (10), 839-847, 2012 | 809 | 2012 |
| A roadmap for interpreting 13C metabolite labeling patterns from cells JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ... Current opinion in biotechnology 34, 189-201, 2015 | 645 | 2015 |
| Fatty acid carbon is essential for dNTP synthesis in endothelial cells S Schoors, U Bruning, R Missiaen, KCS Queiroz, G Borgers, I Elia, ... Nature 520 (7546), 192-197, 2015 | 605 | 2015 |
| Metabolic pathway alterations that support cell proliferation MG Vander Heiden, SY Lunt, TL Dayton, BP Fiske, WJ Israelsen, ... Cold Spring Harbor symposia on quantitative biology 76, 325-334, 2011 | 343 | 2011 |
| Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation SY Lunt, V Muralidhar, AM Hosios, WJ Israelsen, DY Gui, L Newhouse, ... Molecular cell 57 (1), 95-107, 2015 | 261 | 2015 |
| Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism PJP Aspuria, SY Lunt, L Väremo, L Vergnes, M Gozo, JA Beach, ... Cancer & metabolism 2, 1-15, 2014 | 175 | 2014 |
| PHGDH heterogeneity potentiates cancer cell dissemination and metastasis M Rossi, P Altea-Manzano, M Demicco, G Doglioni, L Bornes, M Fukano, ... Nature 605 (7911), 747-753, 2022 | 137 | 2022 |
| A domino effect in antifolate drug action in Escherichia coli YK Kwon, W Lu, E Melamud, N Khanam, A Bognar, JD Rabinowitz Nature chemical biology 4 (10), 602-608, 2008 | 119 | 2008 |
| The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function M Wenes, A Jaccard, T Wyss, N Maldonado-Pérez, ST Teoh, A Lepez, ... Cell Metabolism 34 (5), 731-746. e9, 2022 | 107 | 2022 |
| Impact of Ultrathin C60 on Perovskite Photovoltaic Devices D Liu, Q Wang, CJ Traverse, C Yang, M Young, PS Kuttipillai, SY Lunt, ... ACS nano 12 (1), 876-883, 2018 | 106 | 2018 |
| Antifolate-Induced Depletion of Intracellular Glycine and Purines Inhibits Thymineless Death in E. coli YK Kwon, MB Higgins, JD Rabinowitz ACS chemical biology 5 (8), 787-795, 2010 | 98 | 2010 |
| Sialic acid metabolism: a key player in breast cancer metastasis revealed by metabolomics ST Teoh, MP Ogrodzinski, C Ross, KW Hunter, SY Lunt Frontiers in oncology 8, 174, 2018 | 96 | 2018 |
| In vivo evidence for serine biosynthesis-defined sensitivity of lung metastasis, but not of primary breast tumors, to mTORC1 inhibition G Rinaldi, E Pranzini, J Van Elsen, D Broekaert, CM Funk, M Planque, ... Molecular cell 81 (2), 386-397. e7, 2021 | 91 | 2021 |
| Metabolism in cancer metastasis: bioenergetics, biosynthesis, and beyond ST Teoh, SY Lunt Wiley Interdisciplinary Reviews: Systems Biology and Medicine 10 (2), e1406, 2018 | 74 | 2018 |
| Dose-dependent metabolic reprogramming and differential gene expression in TCDD-elicited hepatic fibrosis R Nault, KA Fader, DA Ammendolia, P Dornbos, D Potter, B Sharratt, ... Toxicological Sciences 154 (2), 253-266, 2016 | 74 | 2016 |
| Isotope ratio-based profiling of microbial folates W Lu, YK Kwon, JD Rabinowitz Journal of the American Society for Mass Spectrometry 18, 898-909, 2007 | 72 | 2007 |
| Organic heptamethine salts for photovoltaics and detectors with near‐infrared photoresponse up to 1600 nm M Young, J Suddard‐Bangsund, TJ Patrick, N Pajares, CJ Traverse, ... Advanced Optical Materials 4 (7), 1028-1033, 2016 | 67 | 2016 |
| Integrated analyses of murine breast cancer models reveal critical parallels with human disease JP Rennhack, B To, M Swiatnicki, C Dulak, MP Ogrodzinski, Y Zhang, C Li, ... Nature communications 10 (1), 3261, 2019 | 59 | 2019 |
| Deciphering metabolic rewiring in breast cancer subtypes MP Ogrodzinski, JJ Bernard, SY Lunt Translational Research 189, 105-122, 2017 | 57 | 2017 |
Gregory StephanopoulosW.H. Dow Professor of Chemical Engineering and BiotechnologyVerified email at mit.edu
