Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems N Nasongkla, E Bey, J Ren, H Ai, C Khemtong, JS Guthi, SF Chin, ... Nano letters 6 (11), 2427-2430, 2006 | 1520 | 2006 |
Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases J Morales, L Li, FJ Fattah, Y Dong, EA Bey, M Patel, J Gao, DA Boothman Critical Reviews™ in Eukaryotic Gene Expression 24 (1), 2014 | 718 | 2014 |
Klotho inhibits transforming growth factor-β1 (TGF-β1) signaling and suppresses renal fibrosis and cancer metastasis in mice S Doi, Y Zou, O Togao, JV Pastor, GB John, L Wang, K Shiizaki, ... Journal of Biological Chemistry 286 (10), 8655-8665, 2011 | 644 | 2011 |
cRGD‐functionalized polymer micelles for targeted doxorubicin delivery N Nasongkla, X Shuai, H Ai, BD Weinberg, J Pink, DA Boothman, J Gao Angewandte Chemie 116 (46), 6483-6487, 2004 | 583 | 2004 |
Synthesis and functional analyses of nuclear clusterin, a cell death protein KS Leskov, DY Klokov, J Li, TJ Kinsella, DA Boothman Journal of Biological Chemistry 278 (13), 11590-11600, 2003 | 507 | 2003 |
Ku70 suppresses the apoptotic translocation of Bax to mitochondria M Sawada, W Sun, P Hayes, K Leskov, DA Boothman, S Matsuyama Nature cell biology 5 (4), 320-329, 2003 | 457 | 2003 |
NAD (P) H: quinone oxidoreductase activity is the principal determinant of β-lapachone cytotoxicity JJ Pink, SM Planchon, C Tagliarino, ME Varnes, D Siegel, DA Boothman Journal of Biological Chemistry 275 (8), 5416-5424, 2000 | 453 | 2000 |
Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer B Shannan, M Seifert, K Leskov, J Willis, D Boothman, W Tilgen, ... Cell Death & Differentiation 13 (1), 12-19, 2006 | 403 | 2006 |
An NQO1-and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachone EA Bey, MS Bentle, KE Reinicke, Y Dong, CR Yang, L Girard, JD Minna, ... Proceedings of the National Academy of Sciences 104 (28), 11832-11837, 2007 | 400 | 2007 |
Nuclear clusterin/XIP8, an x-ray-induced Ku70-binding protein that signals cell death CR Yang, K Leskov, K Hosley-Eberlein, T Criswell, JJ Pink, TJ Kinsella, ... Proceedings of the National Academy of Sciences 97 (11), 5907-5912, 2000 | 368 | 2000 |
Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses M Meyers, MW Wagner, HS Hwang, TJ Kinsella, DA Boothman Cancer research 61 (13), 5193-5201, 2001 | 345 | 2001 |
Superparamagnetic iron oxide nanoparticles: amplifying ROS stress to improve anticancer drug efficacy G Huang, H Chen, Y Dong, X Luo, H Yu, Z Moore, EA Bey, DA Boothman, ... Theranostics 3 (2), 116, 2013 | 333 | 2013 |
EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma B Mukherjee, B McEllin, CV Camacho, N Tomimatsu, S Sirasanagandala, ... Cancer research 69 (10), 4252-4259, 2009 | 329 | 2009 |
Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation T Criswell, K Leskov, S Miyamoto, G Luo, DA Boothman Oncogene 22 (37), 5813-5827, 2003 | 306 | 2003 |
β-Lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response SM Planchon, S Wuerzberger, B Frydman, DT Witiak, P Hutson, ... Cancer research 55 (17), 3706-3711, 1995 | 296 | 1995 |
Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis D Xie, C Gore, J Liu, RC Pong, R Mason, G Hao, M Long, W Kabbani, ... Proceedings of the National Academy of Sciences 107 (6), 2485-2490, 2010 | 265 | 2010 |
Inhibition of potentially lethal DNA damage repair in human tumor cells by β-lapachone, an activator of topoisomerase I DA Boothman, DK Trask, AB Pardee Cancer research 49 (3), 605-612, 1989 | 259 | 1989 |
Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia H Ding, H Yu, Y Dong, R Tian, G Huang, DA Boothman, BD Sumer, J Gao Journal of Controlled Release 156 (3), 276-280, 2011 | 255 | 2011 |
Overcoming Endosomal Barrier by Amphotericin B-Loaded Dual pH-Responsive PDMA-b-PDPA Micelleplexes for siRNA Delivery H Yu, Y Zou, Y Wang, X Huang, G Huang, BD Sumer, DA Boothman, ... ACS nano 5 (11), 9246-9255, 2011 | 242 | 2011 |
Identification and characterization of X-ray-induced proteins in human cells DA Boothman, I Bouvard, EN Hughes Cancer Research 49 (11), 2871-2878, 1989 | 237 | 1989 |